Abstract: A pressurized metered dose dispenser (100) for dispensing an aerosol formulation comprising particles of a medicament suspended in liquefied propellant, optionally in combination with one or more excipients, the dispenser comprising an aerosol container (1) equipped with a metered dose valve (10), where a formulation chamber is defined in part by the internal walls of the container, and wherein the dispenser further comprises a porous, fluid permeable, particulate semi-permeable body (40) located within the formulation chamber adjacent to the metered dose valve.

Abstract: Use of ceramic powder injection molding for the manufacture of a ceramic component of a medicinal pressurized metered dose dispenser, in particular a metered dose inhaler.

Abstract: A pressurized metered dose dispenser (100) for dispensing an aerosol formulation comprising particles of a medicament suspended in liquefied propellant, optionally in combination with one or more excipients, the dispenser comprising an aerosol container (1) equipped with a metered dose valve (10), where a formulation chamber is defined in part by the internal walls of the container, and wherein the dispenser further comprises a porous, fluid permeable, particulate semi-permeable body (40) located within the formulation chamber adjacent to the metered dose valve.

Abstract: A dry powder inhaler comprises a housing that has a portion that receives a dose of powdered medicament, a patient port that is placed in fluid communication with a patient; an inhalation passageway in communication with the patient port, a deagglomerator that deagglomerates or assists in aerosolization of the dose of powdered medicament; an electric powered device that drives the deagglomerator; a patient-independent energy output source that drives the electric powered device, a detector that detects inspiratory flow through the inhalation passageway; and a controller for actuating the deagglomerator in response to detection of the inspiratory flow by the detector.

Abstract: An inhalation device for dry powder containing a chamber capable of receiving a dose of powdered medicament. The chamber is in communication with a patient port in the form of a mouthpiece or nasal adapter. The inhalation device also contains a deagglomeration/aerosolization apparatus capable of deagglomerating and/or aerosolizing a dose of powdered medicament and is operable by a patient-independent energy output source. The inhalation device further includes detection apparatus that ascertains patient inspiration through the patient port, and a control apparatus that actuates the deagglomeration/aerosolization apparatus in response to detection of patient inspiration.