Abstract: The present invention relates generally to the generation of cells of mesodermal lineage. More particularly, the present invention contemplates a method for the preparation of differentiated or partially differentiated mesodermal cells and their use in tissue repair, regeneration and/or augmentation therapy. The identification and generation of the mesodermal cells further provides a source of transcriptome or proteome data to assess the expression profile of genes associated with the maintenance of mesodermal cells as well as their differentiation, proliferation, expansion and/or renewal potential.

Abstract: A method for reprogramming differentiated or partially differentiated cells to a less differentiated or dedifferentiated state, which method includes providing a karyoplast of a differentiated or partially differentiated cell; and a source of multinucleate, aneuploid, euploid or polyploid multipotent or pluripotent cells, or morula or early embryos, or derivatives thereof; and placing the karyoplast in intimate contact with the multipotent or pluripotent cells, or morula or early embryos or derivatives thereof under conditions sufficient to permit at least partial reprogramming of the cells.

Abstract: A method of producing neurectoderm cells, which method includes providing a source of early primitive ectoderm-like (EPL) cells; a conditioned medium as hereinbefore defined; or an extract therefrom exhibiting neural inducing properties; and contacting the EPL cells with the conditioned medium, for a time sufficient to generate controlled differentiation to neurectoderm cells.

Abstract: A method for producing differentiated or partially differentiated neurons which method includes providing

Abstract: A method for the preparation of cells of ectodermal or endodermal lineages, of high purity which method includes