Abstract: A composition for three-dimension (3D) printing, a method for 3D printing, and a resulting article having porous structure are provided. Such a composition includes from 50% to 100% by weight of a base polymer comprising polyolefin (such as ultra-high molecular weight polyethylene), from 0% to 50% by weight of a glue polymer (such as HDPE or PP), and optionally additive. A composition can be applied in a layer, and the base polymer and the glue polymer each has a predetermined size or size distribution. The composition is sintered in a selected area to form a layer of a solid article, which has a predetermined pore size or pore size distribution. The predetermined particle size or size distribution for each of the base polymer and the glue polymer is determined through computer simulation based on the predetermined pore size or pore size distribution in the layer of the solid article.

Abstract: A composition for three-dimension (3D) printing, a method for 3D printing, and a resulting article having porous structure are provided. Such a composition includes from 50% to 100% o by weight of a base polymer comprising polyolefin (such as ultra-high molecular weight polyethylene), from 0% to 50% by weight of a glue polymer (such as HDPE or PP), and optionally additive. A composition can be applied in a layer, and the base polymer and the glue polymer each has a predetermined size or size distribution. The composition is sintered in a selected area to form a layer of a solid article, which has a predetermined pore size or pore size distribution. The predetermined particle size or size distribution for each of the base polymer and the glue polymer is determined through computer simulation based on the predetermined pore size or pore size distribution in the layer of the solid article.

Abstract: A composition for three-dimension (3D) printing, a method for 3D printing, and a resulting article having porous structure are provided. Such a composition includes from 50% to 100%o by weight of a base polymer comprising polyolefin (such as ultra-high molecular weight polyethylene), from 0% to 50% by weight of a glue polymer (such as HDPE or PP), and optionally additive. A composition can be applied in a layer, and the base polymer and the glue polymer each has a predetermined size or size distribution. The composition is sintered in a selected area to form a layer of a solid article, which has a predetermined pore size or pore size distribution. The predetermined particle size or size distribution for each of the base polymer and the glue polymer is determined through computer simulation based on the predetermined pore size or pore size distribution in the layer of the solid article.

Abstract: A pressure sensor measuring element for a pressure sensor operates to detect pressure in a combustion space of an internal combustion engine. The pressure sensor measuring element includes a separating diaphragm, a plunger for the transmission of deflections of the separating diaphragm to a force measuring element, and with a sleeve which receives the plunger. The sleeve is closed by the separating diaphragm at a first end intended to face the combustion space and is designed to hold the force measuring element at the opposite second end. Accordingly, the pressure sensor measuring element can be produced more cost-effectively. Furthermore, the plunger can be produced in one piece with the separating diaphragm as a diaphragm/plunger unit, and the sleeve and the diaphragm/plunger unit can be formed from the same metal material.

Abstract: The present disclosure is directed to an adhesion promoter composition comprising of a solvent and a functionalized olefin block copolymer, and articles with the adhesion promoter composition applied thereto. The adhesion promoter composition can be halogen-free.

Abstract: A pressure sensor measuring element for a pressure sensor operates to detect pressure in a combustion space of an internal combustion engine. The pressure sensor measuring element includes a separating diaphragm, a plunger for the transmission of deflections of the separating diaphragm to a force measuring element, and a sleeve which receives the plunger. The sleeve is closed by the separating diaphragm at a first end intended to face the combustion space and is designed to hold the force measuring element at the opposite second end. Accordingly, the pressure sensor measuring element can be produced more cost-effectively. Furthermore, the plunger can be produced in one piece with the separating diaphragm as a diaphragm/plunger unit, and the sleeve and the diaphragm/plunger unit can be formed from the same metal material.

Abstract: The present invention provides methods for producing exogenous and chimeric antibodies in avians. One aspect of the present invention is a method of producing avians or avian cells lacking endogenous immunoglobulin light chain and heavy chain loci, or portions thereof, and having at least a portion of at least one exogenous immunoglobulin locus. The present invention provides a method for obtaining an avian cell with a deletion in an endogenous immunoglobulin locus by by introducing a targeting construct comprising two regions of sequences which are homologous to the 5′ and 3′ flanking sequences of the region to be deleted in the wild-type locus. In addition, the invention provides methods for inserting exogenous immunoglobulin gene loci into the genome of an avian cell. A second aspect of the invention is the generation of transgenic avian species or transgenic avian cells for producing chimeric antibodies.

Abstract: A method for diagnosing clinically distinct embryonal and alveolar subtypes of rhabdomyosarcoma, including contacting a reagent including an antibody that specifically binds myogenin with a sample that includes at least one rhabdomyosarcoma cell or at least one extract of at least one rhabdomyosarcoma cell, detecting the binding of the antibody to the sample to determine the presence, absence, or amount of myogenin in the sample, and diagnosing clinically distinct embryonal and alveolar subtypes of rhabdomyosarcoma, alveolar rhabdomyosarcoma having an increased amount of binding as compared to embryonal rhabdomyosarcoma.

Abstract: The present invention provides methods for producing exogenous and chimeric antibodies in avians. One aspect of the present invention is a method of producing avians or avian cells lacking endogenous immunoglobulin light chain and heavy chain loci, or portions thereof, and having at least a portion of at least one exogenous immunoglobulin locus. The present invention provides a method for obtaining an avian cell with a deletion in an endogenous immunoglobulin locus by by introducing a targeting construct comprising two regions of sequences which are homologous to the 5′ and 3′ flanking sequences of the region to be deleted in the wild-type locus. In addition, the invention provides methods for inserting exogenous immunoglobulin gene loci into the genome of an avian cell. A second aspect of the invention is the generation of transgenic avian species or transgenic avian cells for producing chimeric antibodies.