Abstract: A method of promoting neural stem cell differentiation is provided comprising exposing neural stem cells to a dopamine D4 receptor antagonist.

Abstract: A method of treating a brain tumour such as glioblastoma in a mammal is provided comprising administering to the mammal a DRD4 antagonist.

Abstract: A method of manufacturing an inductor embedded into a semiconductor chip package (100) is described, which method comprises providing a carrier (102; 202; 302) having, between a first side and an opposite second side, a first conductive layer (104; 503), an intermediate layer (205; 505), a second conductive layer (106; 504), forming an inductor and contact pads for the chip by patterning the first conductive layer (104; 503) from the first side of the carrier (102; 202; 302), assembling the chip and providing an encapsulation (514) and forming terminals of the package, by patterning the second conductive layer (106; 504) from the second side of the carrier.

Abstract: A dual or multiple row package (300) is provided which comprises a first plurality of terminals (303, 304, 305) and a second plurality of terminals (306, 307), which first and second plurality of terminals are exposed outside the encapsulation at a first side of the package. The terminals of the first plurality of terminals (303, 304, 305) are arranged in a first row (301), wherein a distance between each pair of adjacent terminals in the first row (301) is greater or equal than a first threshold value. Furthermore, the terminals of the second plurality of terminals (306, 307) are arranged in a second row (302), wherein a distance between each pair of adjacent terminals in the second row (302) is greater or equal than a second threshold and a distance between the first row (301) and the second row (302) is smaller than at least the first threshold value.

Abstract: A dual or multiple row package (300) is provided which comprises a first plurality of terminals (303, 304, 305) and a second plurality of terminals (306, 307), which first and second plurality of terminals are exposed outside the encapsulation at a first side of the package. The terminals of the first plurality of terminals (303, 304, 305) are arranged in a first row (301), wherein a distance between each pair of adjacent terminals in the first row (301) is greater or equal than a first thresholdvalue. Furthermore, the terminals of the second plurality of terminals (306, 307) are arranged in a second row (302), wherein a distance between each pair of adjacent terminals in the second row (302) is greater or equal than a second threshold and a distance between the first row (301) and the second row (302) is smaller than at least the first threshold value.

Abstract: A method of manufacturing an inductor embedded into a semiconductor chip package (100) is described, which method comprises providing a carrier (102; 202; 302) having, between a first side and an opposite second side, a first conductive layer (104; 503), an intermediate layer (205; 505), a second conductive layer (106; 504), forming an inductor and contact pads for the chip by patterning the first conductive layer (104; 503) from the first side of the carrier (102; 202; 302), assembling the chip and providing an encapsulation (514) and forming terminals of the package, by patterning the second conductive layer (106; 504) from the second side of the carrier.

Abstract: Isolated medulloblastoma-forming clonogenic cells are provided which are useful to form stable cell lines as well as a non-human animal models of medulloblastoma that mimic human medulloblastoma, thereby providing a means to screen for candidate therapeutic compounds.