Patents by Inventor Peter E. Daddona

Peter E. Daddona has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6322808
    Abstract: A device (3) comprising a sheet member (6) having a plurality of microprotrusions (4) for penetrating the skin and a rigid support (15) contacting and extending across the sheet member (6) for transmitting an applied force evenly across the length and width of the sheet member (6) to reproducibly and reliably penetrate the skin with the microprotrusions (4).
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: November 27, 2001
    Assignee: ALZA Corporation
    Inventors: Joseph Creagan Trautman, Patrick S.-L. Wong, Peter E. Daddona, Hyunok Lynn Kim, Michael G. Zuck
  • Patent number: 6203817
    Abstract: Transdermal compositions, devices, and methods for the administration of a drug at reduced skin irritation levels are disclosed. More particularly, this invention relates to novel methods, compositions, and devices for the reduction or elimination of irritation or sensitization caused by an irritating or sensitizing drug when it is delivered transdermally. According to a preferred embodiment, transdermal administration of a drug salt of a non-zwitterionic drug is disclosed wherein the drug salt comprises a combination of surface activity and a low octanol-water partition coefficient. Such drug salts have been found to reduce irritation or sensitization to the drug being delivered while achieving therapeutically effective transdermal fluxes.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: March 20, 2001
    Assignee: ALZA Corporation
    Inventors: Michel J. N. Cormier, Peter E. Daddona, Juanita A. Johnson
  • Patent number: 6091975
    Abstract: An agent detecting device comprising a plate (6) having a plurality of microprotrusions (4) for piercing the skin of a patient. Each of the microprotrusions (4) having an electrode (14, 16 and 18) thereon for detecting the presence of an agent in the patient's interstitial fluid.
    Type: Grant
    Filed: April 1, 1998
    Date of Patent: July 18, 2000
    Assignee: Alza Corporation
    Inventors: Peter E. Daddona, Gregory T. Fieldson, Avtar S. Nat, Wei-Qi Lin
  • Patent number: 5995869
    Abstract: A device and method are provided for reducing or preventing skin sensitization in electrotransport drug delivery. The method involves co-administration of a countersensitizing agent, comprising cis-urocanic acid or an analog thereof, with the drug delivered via electrotransport. Novel drug reservoirs and electrotransport drug delivery systems, formulated with a countersensitizing agent as described herein, are provided as well.
    Type: Grant
    Filed: June 11, 1997
    Date of Patent: November 30, 1999
    Assignee: Alza Corporation
    Inventors: Michel J. N. Cormier, James A. Matriano, Ronald P. Haak, Peter E. Daddona
  • Patent number: 5026537
    Abstract: This invention pertains to a method of imaging atherosclerotic plaque using radiolabeled monoclonal antibodies that are specific for activated platelets or activated endothelial cells. The method is capable of determining the site of endothelial injury. This method involves the administration of a platelet-specific labeled monoclonal antibody or antibody fragment to a patient. The antibody is allowed to accumulate at the plaque site and the plaque is then scanned with a photoscanner. The detected signals are then converted into an image of the plaque.
    Type: Grant
    Filed: April 6, 1989
    Date of Patent: June 25, 1991
    Assignee: Centocor, Inc.
    Inventors: Peter E. Daddona, Harvey J. Berger, Rodger P. McEver
  • Patent number: 4946668
    Abstract: Method using technetium-99m imaging agents for the study, detection or diagnosis of tumors. The imaging agents comprise a complex of technetium-99m and glucarate.
    Type: Grant
    Filed: November 22, 1988
    Date of Patent: August 7, 1990
    Assignee: Centocor, Inc.
    Inventors: Peter E. Daddona, Koon Y. Pak, Mark Nedelman