Patents by Inventor Peter E. Keane

Peter E. Keane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5026711
    Abstract: Compounds represented by the general formula: ##STR1## in which R.sub.1 and R.sub.2 are selected from hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.2 -C.sub.6 alkenyl , phenyl or benzyl or R.sub.1 and R.sub.2 form together with the nitrogen atom to which they are attached a C.sub.4 -C.sub.8 saturated heterocycle, R.sub.3 is selected from hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl or C.sub.7 -C.sub.9 phenyl-alkyl, R.sub.4 is selected from hydrogen or C.sub.1 -C.sub.4 alkyl, R.sub.5 and R.sub.6 are selected from hydrogen or halogen, C.sub.1 -C.sub.3 or alkoxy, nitro or trifluoromethyl; Z is selected from OH, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.4 alkyl, benzyl, C.sub.4 -C.sub.6 aryl with or without a heteroatom, or NR.sub.8 R.sub.9, R.sub.8 and R.sub.9 being selected from hydrogen, C.sub.1 -C.sub.4 alkyl, phenyl or benzyl; R.sub.10 is selected from hydrogen, C.sub.1 -C.sub.
    Type: Grant
    Filed: June 6, 1989
    Date of Patent: June 25, 1991
    Assignee: Sanofi
    Inventors: Etienne Mendes, Jean-Claude Vernieres, Peter E. Keane, Andre Bachy
  • Patent number: 4996213
    Abstract: Compounds represented by the general formula ##STR1## in which R.sub.1 and R.sub.2 are independently selected from hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl or benzyl, or R.sub.1 and R.sub.2 may form together with the nitrogen atom to which they are attached a C.sub.4 -C.sub.8 saturated heterocycle, R.sub.3 and R.sub.4 are independently selected from hydrogen or C hd 1-C.sub.6 alkyl, R.sub.5 is selected from hydrogen or halogen, or C.sub.1 -C.sub.4 alkyl, C.sub.1 -C hd 4 alkoxy, nitro or trifluoromethyl, n is 1, 2 or 3, and one of the symbols A, B, C or D represents N and the others represent CH, as well as the N-oxids and the the pharmaceutically acceptable acid addition salts and their salts with bases. The compounds have nervous system affecting properties.
    Type: Grant
    Filed: June 6, 1989
    Date of Patent: February 26, 1991
    Assignee: SANOFI
    Inventors: Etienne Mendes, Jean-Claude Vernieres, Jacques Simiaud, Peter E. Keane
  • Patent number: 4835163
    Abstract: The present invention concerns new derivatives of 4-oxo-1,4-dihydro-quinoline 3-carboxamide, answering to the following general formula: ##STR1## in which: R.sub.1 represents a linear or branched lower alkyl radical, containing from 1 to 5 carbon atoms; an alkenyl or alkynyl radical containing from 2 to 5 carbon atoms; or a cycloalkyl radical containing from 3 to 5 carbon atoms,R.sub.2 represents an alkyl radical containing from 1 to 4 carbon atoms, n is equal to 1 or 2,X represents a hydrogen, a halogen, a lower alkoxy or alkyl group.The invention also concerns their application as medicaments and the compositions containing them.
    Type: Grant
    Filed: January 15, 1987
    Date of Patent: May 30, 1989
    Assignee: Sanofi
    Inventors: Jean-Claude Verniere, Jacques Simiand, Peter E. Keane