Patents by Inventor Peter E. Prevelige,

Peter E. Prevelige, has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of monitoring HIV assembly and maturation
    Publication number: 20010036627
    Abstract: The present invention provides methods to characterize the structure, stability, and intersubunit interfaces between the matrix, capsid, and nucleocapsid domains of the Gag polyprotein during HIV capsid assembly and maturation. A method of screening for compounds that promote or inhibit viral assembly and maturation is disclosed. A novel mass spectrometry based approach to measure hydrogen/deuterium exchange profiles is also disclosed. Quantitative data resulted from these studies may lead to well defined capsid assembly assays that can be adapted for rapid antiviral drug screening.
    Type: Application
    Filed: March 6, 2001
    Publication date: November 1, 2001
    Inventor: Peter E. Prevelige,