Abstract: An intravenous delivery system is disclosed for formulating an intravenously administrable solution in the delivery system. The delivery system comprises means for transferring a fluid and for mixing the fluid with a drug in the delivery system.

Abstract: The bladder assembly of this invention has spaced apart inlet and outlet means and the bladder is capable of expanding and contracting radially and axially upon inflation and deflation. When deflated the lumen of the bladder is substantially completely filled by lumen filling means, which in a preferred embodiment, protect the bladder from being punctured by the hypodermic needle used to fill and inflate the bladder. The lumen filling means resists the compressive load applied during insertion of the needle and maintains the inlet and outlet means in spaced apart relationship while providing substantially no resistance to the axial expansion of the bladder. By having the lumen of the bladder filled with the lumen filling means when the bladder is deflated, before its subsequent inflation and deflation, substantially complete expulsion of the fluid contents of the bladder can be obtained.

Abstract: A portable elastomeric bladder-powered infusor for dispensing drug in liquid form under pressure at a predetermined flow rate is disclosed. The main elements of the infusor are a tubular housing, a plug/flow control assembly fixed in one end of the bladder, an axially slidable piston/filling port assembly within the housing, and a tubular bladder. The plug and piston assemblies each has an axial post about which the bladder ends are attached. When the bladder is not charged with drug, the posts fill the bladder's lumen and their ends abut. Drug is charged to the infusor by inserting a drug-filled syringe into the open end of the housing with the syringe's needle entering an axial bore in the piston, penetrating a septum that blocks the bore, and extending into the axial post. The force exerted on the piston by the syringe is transmitted to the fixed plug assembly via the axial posts. Drug is plunged from the syringe causing the posts to separate and the bladder to expand axially and radially.