Patents by Inventor Peter F. Heinstein

Peter F. Heinstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5635382
    Abstract: A method is provided for enhancing transmembrane transport of exogenous molecules. The method comprises contacting a membrane of a living cell with a complex formed between said molecules and ligands selected from biotin, biotin analogs and other biotin receptor-binding ligands, and/or folic acid, folate analogs and other folate receptor-binding ligands to initiate receptor mediated transmembrane transport of the ligand complex. The method is used for the efficient delivery of peptides, proteins, nucleic acids and other compounds capable of modifying cell function into plant, animal, yeast, and bacterial cells.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: June 3, 1997
    Assignee: Purdue Research Foundation
    Inventors: Philip S. Low, Mark A. Horn, Peter F. Heinstein
  • Patent number: 5416016
    Abstract: A method is provided for enhancing transmembrane transport of exogenous molecules. The method comprises contacting a membrane of a living cell with a complex formed between said molecules and ligands selected from biotin, biotin analogs and other biotin receptor-binding ligands, and/or folic acid, folate analogs and other folate receptor-binding ligands to initiate receptor mediated transmembrane transport of the ligand complex. The method is used for the efficient delivery of peptides, proteins, nucleic acids and other compounds capable of modifying cell function into plant, animal, yeast, and bacterial cells.
    Type: Grant
    Filed: March 13, 1992
    Date of Patent: May 16, 1995
    Assignee: Purdue Research Foundation
    Inventors: Philip S. Low, Mark A. Horn, Peter F. Heinstein
  • Patent number: 5108921
    Abstract: A method is provided for enhancing transmembrane transport of exogenous molecules. The method comprises contacting a membrane of a living cell with a complex formed between said molecules and ligands selected from biotin, biotin analogs and other biotin receptor-binding ligands, and/or folic acid, folate analogs and other folate receptor-binding ligands to initiate receptor mediated transmembrane transport of the ligand complex. The method is used for the efficient delivery of peptides, proteins, nucleic acids and other compounds capable of modifying cell function into plant, animal, yeast, and bacterial cells.
    Type: Grant
    Filed: March 28, 1990
    Date of Patent: April 28, 1992
    Assignee: Purdue Research Foundation
    Inventors: Philip S. Low, Mark A. Horn, Peter F. Heinstein