Abstract: A footwear article includes a footwear upper defining a foot-receiving cavity with a heel region and defining an ankle opening, the footwear upper including an ankle collar at the ankle opening. The footwear article has a sole structure secured to the footwear upper and underlying the foot-receiving cavity, the sole structure including a strobel and a midsole. The footwear article including a collar support disposed inward of an exterior layer of the footwear upper at the heel region, and extending from the sole structure to the ankle opening. The ankle collar is movable from a raised state positioned farther from the sole to a lowered state positioned closer to the sole during donning, and wherein the collar support has a shoehorn structure operable to move a portion of the ankle collar rearward in a longitudinal direction as the ankle collar moves from the raised state to the lowered state.

Abstract: A footwear article includes a heel structure that returns an ankle collar from a second state that is conducive to donning up to a first state that secures the wearer's foot during wear. The footwear article includes an upper having a foot insertion opening. The foot-insertion opening defines a first circumference when the heel structure is in the first state, and wherein the heel structure expands the foot-insertion opening to a second circumference when the heel structure is in the second state, such that the second circumference is larger than the first circumference.

Abstract: An ear-wearable electronic device includes a first near-field communication (NFC) device and a transfer region configured to facilitate transfer of a wearable sensor unit into an ear of a wearer or onto an outer ear of the wearer or a surface of the wearer's head adjacent the outer ear. The wearable sensor unit comprises electronic circuitry comprising a second NFC device configured to communicatively couple to the first NFC device and facilitate wireless transfer of power from the ear-wearable electronic device to the wearable sensor unit and wireless transfer of data at least from the wearable sensor unit to the ear-wearable electronic device, and one or more sensors configured to measure at least one physiologic parameter or physiologic condition of the wearer. The wearable sensor unit and the ear-wearable electronic device are configured to remain mechanically decoupled from one another subsequent to deployment of the wearable sensor unit.

Abstract: An ear-worn electronic device comprises a housing configured to fit at least partially in an ear of a wearer, a power source situated in the housing, and a temperature sensor arrangement situated in or on the housing and coupled to the power source. The temperature sensor arrangement is configured to generate sensor signals in response to heat generated in the wearer's ear and a controller, situated in the housing and coupled to the power source and the temperature sensor arrangement, is configured to assess a fit of the device using the sensor signals.

Abstract: An ear-worn electronic device comprises a housing configured for deployment in, on or about an ear of a wearer and a power source situated in the housing. A sensor is situated in or on the housing and coupled to the power source. The sensor is configured to generate a sensor signal representative of motion of the wearer’s head and relative motion between the sensor and skin of the wearer’s ear resulting from the wearer’s head motion. A controller is situated in the housing and coupled to the power source and the sensor. The controller is configured to assess a fit of the device using the sensor signal.

Abstract: An ear-wearable electronic device comprises a shell having a uniquely-shaped outer surface that corresponds uniquely to an ear geometry of a wearer of the device. The shell comprises a window through a proximal portion of the shell and positioned at ear canal tissue when the device is deployed in the wearer's ear. An optical sensor, such as a photoplethysmograph (PPG) sensor, is disposed in the window. A biasing member has a uniquely-shaped outer surface that corresponds uniquely to a geometry of at least a portion of a pinna of the wearer's ear. The biasing member is configured to generate a biasing force sufficient to maintain static positioning of the optical sensor relative to the ear canal tissue during wearer body and jaw movement.

Abstract: An ear-wearable electronic device has a shell with an outer surface. A mounting void goes through the outer surface of the shell and exposes an internal volume of the shell. The mounting void is located at an ear-contacting region of the shell. The ear-wearable device includes a photoplethysmography sensor assembly having an optical transmission structure mounted in the mounting void and having a distal end exposed proximate the outer surface. The distal end of the optical transmission structure conforms to the outer surface of the shell at the ear-contacting region. The distal end is in contact with ear tissue of a user of the ear-wearable electronic device during use.

Abstract: Embodiments are directed to an electronic device configured to measure temperature from within an ear canal having a first bend, a second bend, and a tympanic membrane. The device comprises an enclosure comprising an in-canal section dimensioned for deployment in the ear canal. The in-canal section comprises a trough extending axially along at least a portion of the in-canal section and arranged to be positioned between the first bend and the tympanic membrane when the in-canal section is fully deployed in the ear canal. A temperature sensor is disposed in the trough. The temperature sensor comprises a flexible circuit board, a distal temperature sensor disposed on the flexible circuit board, and a proximal temperature sensor disposed on the flexible circuit board and situated proximal of, and spaced apart from, the distal temperature sensor in an outer ear direction.

Abstract: A system may have a rechargeable hearing instrument with a power source, an ultraviolet (UV) sensor configured to convert received UV light into electrical power and charging circuitry coupled to the UV sensor and to the power source. The charging circuitry may use the electrical power to charge the power source. A charger may have a charging cavity configured to receive the rechargeable hearing instrument. A power source within the charger powers a UV light source located within the charger configured to provide UV light to the UV sensor of the rechargeable hearing instrument when the rechargeable hearing instrument is placed within the charging cavity.

Abstract: An ear-wearable device, such as a hearing aid or earbud, includes a plurality of biometric sensors configured to generate sensor measurements indicative of at least an aspect of contact between the housing of the ear-wearable device and the ear canal of the user, and compares the sensor measurements to a stored profile in order to determine whether an authorized user is wearing the ear-wearable device.

Abstract: The present invention relates in part to hWART nucleic acid molecules. The invention also relates in part to nucleic acid molecules encoding portions of hWART full-length proteins, nucleic acid vectors containing hWART nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that modulate the function of an hWART polypeptide. Also disclosed are methods for diagnosing abnormal cell proliferative conditions in an organism using hWART-related molecules or compounds.

Abstract: The present invention relates to kinase polypeptides, nucleotide sequences encoding the kinase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various kinase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the of PTK's and STK's have been identified and their protein structure predicted.

Abstract: A supply chain management system (1) has a server (2) and a tracking database (3) linked to multiple remote transaction sites (10, 15, 16, 17, 18). A manufacturing facility (10) manufactures a product (12) and the system (1) assigns a unique reference to it. This reference includes a component identifying the location (10) of production. Each subsequent operation involving the product along the supply chain generates transaction data and the system (1) records a transaction record for it. If the product is modified such as by splitting the pallet, the original reference is terminated and no more transaction records can be generated for it. The modified product is assigned a fresh reference and a series of tracking records is generated as it moves along the supply chain.

Abstract: A precoat renewal system for a filter, such as a disc filter is provided. The renewal system includes a plurality of nozzles coupled to spray piping and valving with each nozzle being positioned for spraying an area of one side of a disc. The nozzles and at least a portion of the spray piping are movable such that the nozzles may be displaced relative to the discs. The nozzles and piping are arranged in groups or zones with each zone covering a specified percentage of the discs in the filter and each zone representing about 40% or less of the surface area of the filter media of the discs in the filter. Each zone is configured such that high pressure fluid may be supplied to that particular zone for removal of a precoat layer on the disc. The system may be configured so that other zones may be concurrently washed with a lower pressure fluid. The zones may be sequentially or otherwise segmentally provided with high pressure fluid until the precoat layers of each respective zone have been removed and renewed.

Abstract: The present invention relates to phosphatase polypeptides having the amino acid sequence of SEQ ID NO:23 or SEQ ID NO:24, disclosed herein. The invention also relates to nucleotide sequences encoding the phosphatase polypeptides, vectors and recombinant cells comprising such sequences, antibodies having binding affinity to the phosphatase polypeptides, and other products. Included in the invention are methods for identifying modulators of the phosphatase polypeptides, as well as methods for diagnosing and treating various conditions related to the phosphatase polypeptides.

Abstract: A supply chain management system (1) has a server (2) and a tracking database (3) linked to multiple remote transaction sites (10, 15, 16, 17, 18). A manufacturing facility (10) manufactures a product (12) and the system (1) assigns a unique reference to it. This reference includes a component identifying the location (10) of production. Each subsequent operation involving the product along the supply chain generates transaction data and the system (1) records a transaction record for it. If the product is modified such as by splitting the pallet, the original reference is terminated and no more transaction records can be generated for it. The modified product is assigned a fresh reference and a series of tracking records is generated as it moves along the supply chain.

Abstract: The present invention relates to phosphatase polypeptides, nucleotide sequences encoding the phosphatase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various phosphatase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the MAP kinase hosphatase PTP's and STP's have been identified and their protein structure predicted.

Abstract: The present invention relates in part to hWART nucleic acid molecules. The invention also relates in part to nucleic acid molecules encoding portions of hWART full-length proteins, nucleic acid vectors containing hWART nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that modulate the function of an hWART polypeptide. Also disclosed are methods for diagnosing abnormal cell proliferative conditions in an organism using hWART-related molecules or compounds.

Abstract: The present invention relates in part to hWART nucleic acid molecules. The invention also relates in part to nucleic acid molecules encoding portions of hWART full-length proteins, nucleic acid vectors containing hWART nucleic acid molecules, recombinant cells containing such nucleic acid vectors, polypeptides purified from such recombinant cells, antibodies to such polypeptides, and methods of identifying compounds that modulate the function of an hWART polypeptide. Also disclosed are methods for diagnosing abnormal cell proliferative conditions in an organism using hWART-related molecules or compounds.

Abstract: The present invention relates to phosphatase polypeptides, nucleotide sequences encoding the phosphatase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various phosphatase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the MAP kinase phosphatase PTP's and STP's have been identified and their protein structure predicted.