Abstract: Techniques for modifying an application data set may include receiving a request to modify a storage group of logical devices used by an application; and performing processing that modifies, in accordance with the request, the storage group and an existing remote replication configuration. The processing may include verifying that the logical devices of the storage group are protected by remote replication performed in accordance with the existing remote replication configuration; analyzing the existing remote replication configuration and generating analysis information; performing, in accordance with the analysis information and the request, a first modification to the existing remote replication configuration; and performing, in accordance with the request, a second modification to the storage group. The request may add logical devices to the storage group or remove logical devices from the storage group and accordingly modify the existing remote replication configuration.

Abstract: Techniques for modifying an application data set may include receiving a request to modify a storage group of logical devices used by an application; and performing processing that modifies, in accordance with the request, the storage group and an existing remote replication configuration. The processing may include verifying that the logical devices of the storage group are protected by remote replication performed in accordance with the existing remote replication configuration; analyzing the existing remote replication configuration and generating analysis information; performing, in accordance with the analysis information and the request, a first modification to the existing remote replication configuration; and performing, in accordance with the request, a second modification to the storage group. The request may add logical devices to the storage group or remove logical devices from the storage group and accordingly modify the existing remote replication configuration.

Abstract: Disclosed herein are methods for predicting pore pressure in geological environments. Aspects of the disclosure describe details relating to performing geomechanical modeling for a target location in order to obtain a surrogate stress at the target location and predicting pore pressure by coupling velocity data (e.g., seismic and/or sonic) with the surrogate stress. Aspects of the disclosure can be used to obtain improved predictions of pore pressure in subsurface environments, especially in basins with complex geologic histories, and in practice to improve the safe design of casing, wellbore trajectory, and overall borehole stability.

Abstract: A poly(methyl methacrylate) (PMMA) membrane having a highly porous, reticulated, 3-D structure suitable for lateral flow diagnostic applications is described. Also described is a method for producing a poly(methyl methacrylate) (PMMA) membrane that comprises the steps of mixing a suitable amount of PMMA, a solvent and a optionally one of either a co-solvent or a non-solvent to produce a solution, casting a thin film of the solution onto a support, and removal of the solvent from the solution to produce the PMMA membrane. A lateral flow diagnostic device comprising a highly porous PMMA membrane as a reaction membrane is also described.

Abstract: This invention relates generally to the inhibition of cytomegalovirus (CMV) reactivation in immunosuppressed subjects, including subjects receiving hematopoietic or solid organ transplants. The present invention is particularly relevant for the treatment of CMV reactivation or infection in subjects with graft-versus-hosts disease (GVHD) or under immunosuppressive therapy.

Abstract: Altitude determining circuitry for use in a User Equipment (UE) of a wireless communication network is provided. The circuitry comprises a receiver to receive at least one pressure parameter representative of a plurality of indoors pressure measurements from a respective plurality of indoors pressure measurement units located inside a building at different altitudes. The altitude determining circuitry also has processing circuitry to receive from a pressure sensor in the User Equipment a local pressure measurement at the UE and the processor determines an indoors altitude of the UE using the at least one pressure parameter and the UE local pressure. An integrated circuit for a Global Navigate Satellite System comprising the altitude determining circuitry and an indoors pressure measurement unit having a sensor for making a pressure measurement and a transmitter for transmitting the pressure measurement to the UE or to a further indoors pressure measurement unit are also provided.

Abstract: Methods and apparatus disclosed herein may facilitate the evaluation of time-correlated operational data associated with a mobile platform more effectively by presenting the relevant data in ways that are relatively straightforward to interpret and more favorable to the identification of potential root causes. In some aspects, the methods and apparatus disclosed herein may facilitate the evaluation of multiple systems simultaneously at different points in time to study the initiation and evolution of one or more faults across one or more systems. In various embodiments, the methods and apparatus disclosed herein make use of graphic user interfaces containing synchronized elements such as two-dimensional plots, fault timelines, alert timelines and status information to facilitate diagnostics of mobile platforms.

Abstract: A poly(methyl methacrylate) (PMMA) membrane having a highly porous, reticulated, 3-D structure suitable for lateral flow diagnostic applications is described. Also described is a method for producing a poly(methyl methacrylate) (PMMA) membrane that comprises the steps of mixing a suitable amount of PMMA, a solvent and a optionally one of either a co-solvent or a non-solvent to produce a solution, casting a thin film of the solution onto a support, and removal of the solvent from the solution to produce the PMMA membrane. A lateral flow diagnostic device comprising a highly porous PMMA membrane as a reaction membrane is also described.

Abstract: Disclosed herein are methods for predicting pore pressure in geological environments. Aspects of the disclosure describe details relating to performing geomechanical modeling for a target location in order to obtain a surrogate stress at the target location and predicting pore pressure by coupling velocity data (e.g., seismic and/or sonic) with the surrogate stress. Aspects of the disclosure can be used to obtain improved predictions of pore pressure in subsurface environments, especially in basins with complex geologic histories, and in practice to improve the safe design of casing, wellbore trajectory, and overall borehole stability.

Abstract: Altitude determining circuitry for use in a User Equipment (UE) of a wireless communication network is provided. The circuitry comprises a receiver to receive at least one pressure parameter representative of a plurality of indoors pressure measurements from a respective plurality of indoors pressure measurement units located inside a building at different altitudes. The altitude determining circuitry also has processing circuitry to receive from a pressure sensor in the User Equipment a local pressure measurement at the UE and the processor determines an indoors altitude of the UE using the at least one pressure parameter and the UE local pressure. An integrated circuit for a Global Navigate Satellite System comprising the altitude determining circuitry and an indoors pressure measurement unit having a sensor for making a pressure measurement and a transmitter for transmitting the pressure measurement to the UE or to a further indoors pressure measurement unit are also provided.

Abstract: Methods and apparatus disclosed herein may facilitate the evaluation of time-correlated operational data associated with a mobile platform more effectively by presenting the relevant data in ways that are relatively straightforward to interpret and more favorable to the identification of potential root causes. In some aspects, the methods and apparatus disclosed herein may facilitate the evaluation of multiple systems simultaneously at different points in time to study the initiation and evolution of one or more faults across one or more systems. In various embodiments, the methods and apparatus disclosed herein make use of graphic user interfaces containing synchronized elements such as two-dimensional plots, fault timelines, alert timelines and status information to facilitate diagnostics of mobile platforms.

Abstract: A positioning system operates by first determining that a user is pedestrian, and then estimating a speed of the user. Having tracked a first signal from one radio transmitter whose position is known, the system attempts to detect additional signals from the one transmitter, in a search space such that the first signal and the or each additional signal are consistent with the estimated speed of the user and with one or more of the signals having been reflected off a reflector in the vicinity of the user. One or more detected additional signals from the one transmitter are then tracked, and candidate measurements, derived from the first signal and the one or more detected additional signals, are provided for use when estimating the position and/or velocity of the user.

Abstract: A sequential estimation method for real-time positioning or navigation systems is performed by, at each iteration: propagating a first state estimate into a state prediction, and then forming a second state estimate, by updating the state prediction using state measurements. The first state estimate is valid at a first time and comprises estimated values of a plurality of state parameters, the plurality of state parameters including at least one state parameter referring to a time earlier than the first time. The second state estimate is valid at a second time and comprises estimated values of said plurality of state parameters, the plurality of state parameters including at least one state parameter referring to a time earlier than the second time. The state measurements comprise measurements relating to state parameters at the second time and measurements relating to state parameters at the time earlier than the second time.

Abstract: A positioning system obtains an estimate of the heading of a body whose position or velocity is to be estimated, for example from a heading sensor such as a gyroscope or accelerometer. Respective signals are tracked from a plurality of transmitters, and a respective Doppler measurement is obtained from each of said tracked signals. For each of the tracked signals, a speed of the body is estimated using the estimate of the heading of the body and the respective Doppler measurement. It is then determined whether the estimated speed of the body is consistent with the signal having been received along a direct path from the transmitter. Signals that provide information about the speed of the body that is inconsistent with the signal having been received along a direct path from the transmitter are then disregarded when estimating the position or velocity of the body.

Abstract: A positioning system operates by first determining that a user is pedestrian, and then estimating a speed of the user. Having tracked a first signal from one radio transmitter whose position is known, the system attempts to detect additional signals from the one transmitter, in a search space such that the first signal and the or each additional signal are consistent with the estimated speed of the user and with one or more of the signals having been reflected off a reflector in the vicinity of the user. One or more detected additional signals from the one transmitter are then tracked, and candidate measurements, derived from the first signal and the one or more detected additional signals, are provided for use when estimating the position and/or velocity of the user.

Abstract: A radiobeacon station is described comprising: a satellite receiver configured to receive satellite navigation data from a satellite; a timing circuit configured to determine a timing scheme based on the satellite navigation data; and a terrestrial transmitter configured to transmit a plurality of beacon signals based on the determined timing scheme.

Abstract: Methods and associated apparatus and programs for computers for operating geolocation devices are provided. The methods include determining the duration of a time interval during which the device is configured to remain active, responsive to a comparison between an estimate of benefit of remaining on for that time interval and an estimate of cost of remaining on for that time interval. The estimates of cost and benefit may be determined in response to user-selected parameters where by the end-user may effect a trade-off between battery life and receiver sensitivity. The methods also include varying the maximum duration of each listening period whereby to conserve battery power.

Abstract: According to one aspect of the invention a system and method for minimizing assembly line manufacturing including an override is provided. Each workstation is equipped with a docking station. A first database is in communication with the programmable controller and the docking station, and the docking station is also in communication with the workstation tools as well as the programmable controller. The override is disposed on a docking station. The system includes a checklist of tasks that each workstation tool is to perform. Accordingly the first database will receive the checklist for each part and will record whether or not each particular part had each of its tasks performed properly. The override may be actuated so as to allow a part to flow downstream the assembly line even though the all the tasks were not completed properly, thus minimizing manufacturing disruptions.

Abstract: According to one aspect of the invention a system and method for minimizing assembly line manufacturing including an override is provided. Each workstation is equipped with a docking station. A first database is in communication with the programmable controller and the docking station, and the docking station is also in communication with the workstation tools as well as the programmable controller. The override is disposed on a docking station. The system includes a checklist of tasks that each workstation tool is to perform. Accordingly the first database will receive the checklist for each part and will record whether or not each particular part had each of its tasks performed properly. The override may be actuated so as to allow a part to flow downstream the assembly line even though the all the tasks were not completed properly, thus minimizing manufacturing disruptions.

Abstract: Methods and associated apparatus and programs for computers for operating geolocation devices are provided. The methods include determining the duration of a time interval during which the device is configured to remain active, responsive to a comparison between an estimate of benefit of remaining on for that time interval and an estimate of cost of remaining on for that time interval. The estimates of cost and benefit may be determined in response to user-selected parameters where by the end-user may effect a trade-off between battery life and receiver sensitivity. The methods also include varying the maximum duration of each listening period whereby to conserve battery power.