Abstract: A method for preparing a stem cell-based, human derived composition containing conditioned cell culture medium is disclosed. The method comprises culturing cells of two or more eukaryotic cell lines to form conditioned culture media, separating the cultured cells from the conditioned culture media, and combining conditioned culture media to form a bioactive composition. This composition is used to treat citrus plants that have been infected by one or more insect-vectored bacterial and/or pathogenic infections such as Citrus Greening. This method consists of applying the conditioned media one or more times to the plant. Use of this treatment may have application to a variety of other agricultural conditions.

Abstract: Systems and methods for tracking a smart container are provided. The methods use sensors of the smart container to detect tampering with the smart container after the container leaves a sender and before the container arrives at a receiver. In particular, the sensors detect when the smart container has been opened by someone other than the receiver (i.e., tampered with) and write the detection of tampering (e.g., the sensor measurement) to a blockchain. Delivery agents use scanners to write their possession or agency over the smart container to the blockchain. Accordingly, the agency of the smart container can be determined if tampering occurs.

Abstract: The disclosure provides systems and methods for tracking a smart container. The methods use sensors of the smart container to detect tampering with the smart container after the container leaves a sender and before the container arrives at a receiver. In particular, the sensors detect when the smart container has been opened by someone other than the receiver (i.e., tampered with) and write the detection of tampering (e.g., the sensor measurement) to a blockchain. Delivery agents use scanners to write their possession or agency over the smart container to the blockchain. Accordingly, the agency of the smart container can be determined if tampering occurs.

Abstract: Non-thermal Atmospheric Plasma (NAP) from a plasma source is mixed with a liquid medium and the resulting compound is applied to the scalp to treat hair loss. The NAP-medium compound may be applied to the surface of the scalp, or produced in situ, or injected into the scalp.

Abstract: A method for preparing a stem cell-based, human derived composition containing conditioned cell culture medium is disclosed. The method comprises culturing cells of two or more eukaryotic cell lines to form conditioned culture media, separating the cultured cells from the conditioned culture media, and combining conditioned culture media to form a bioactive composition. This composition is used to treat citrus plants that have been infected by one or more insect-vectored bacterial and/or pathogenic infections such as Citrus Greening. This method consists of applying the conditioned media one or more times to the plant. Use of this treatment may have application to a variety of other agricultural conditions.

Abstract: A method for preparing a bioactive composition containing conditioned cell culture medium is disclosed. The method comprises culturing cells of two or more eukaryotic cell line to form conditioned culture media, separating the cultured cells from the conditioned culture media, and combining conditioned culture media to form a bioactive composition. Novel bioactive compositions, formulations and their use in treating of a variety of diseases and health conditions are also disclosed.

Abstract: Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (SRM's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and SRM's can be derived from one or more distinct cell lines. The SRM's can further include one or more mucins, cytokines, or growth factors. Exemplary formulations include stem cells and SRMs derived from epithelial stem cells, corneal limbal stem cells, and fibroblasts. Other compositions and methods for formulation thereof are described.

Abstract: There is provided a system and method for rule-based dynamic server-side streaming manifest files. There is provided a method comprising receiving a request to provide a first video content for playback, evaluating a plurality of rules for the first video content, generating a dynamic manifest file referencing the first video content, and providing the dynamic manifest file in response to the request, thereby enabling an application to playback the first video content for output on a display by interpreting the dynamic manifest file. The rules may implement various features such as dynamic advertisement insertion, load balancing, client customization, user and device targeting, enhanced security mechanisms, global announcements, and others. As streaming protocols are widely supported by default on many client platforms, the dynamic manifest files can be utilized in a user friendly and transparent manner compared to client-side solutions requiring cumbersome client software installations.

Abstract: Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (SRM's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and SRM's can be derived from one or more distinct cell lines. The SRM's can further include one or more mucins, cytokines, or growth factors. Exemplary formulations include stem cells and SRMs derived from epithelial stem cells, corneal limbal stem cells, and fibroblasts. Other compositions and methods for formulation thereof are described.

Abstract: Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate.

Abstract: There is provided a system and method for rule-based dynamic server-side streaming manifest files. There is provided a method comprising receiving a request to provide a first video content for playback, evaluating a plurality of rules for the first video content, generating a dynamic manifest file referencing the first video content, and providing the dynamic manifest file in response to the request, thereby enabling an application to playback the first video content for output on a display by interpreting the dynamic manifest file. The rules may implement various features such as dynamic advertisement insertion, load balancing, client customization, user and device targeting, enhanced security mechanisms, global announcements, and others. As streaming protocols are widely supported by default on many client platforms, the dynamic manifest files can be utilized in a user friendly and transparent manner compared to client-side solutions requiring cumbersome client software installations.

Abstract: The present invention provides a method and apparatus for forming a sheet of ductile material by superplastic forming. The gas pressure is varied to control the material flow during the forming process. Accordingly, the gas pressure can be increased or decreased to control the rate of deformation of the workpiece. Accordingly, the method and apparatus contemplates the use of predetermined pressure profiles to reduce the overall forming time.

Abstract: Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate.

Abstract: The present invention provides a method and apparatus for forming a ductile sheet or work piece into a part or component. The method includes using a forming apparatus wherein the workpiece is placed between and upper die and a blank holder and then lowered onto a punch such that continued lowering of the upper die draws the workpiece around the punch. Once the draw process is complete, gas pressure acts on one side of the workpiece to press the workpiece against a forming surface of the punch to complete the forming process.

Abstract: The present invention provides a method and apparatus for forming a sheet of ductal material by superplastic forming. The gas pressure is varied to control the material flow during the forming process. Accordingly, the gas pressure can be increased or decreased to control the rate of deformation of the workpiece. Accordingly, the method and apparatus contemplates the use of predetermined pressure profiles to reduce the overall forming time.

Abstract: A method and apparatus for forming a sheet of ductile material by superplastic forming is disclosed. The method is directed to first creating a pre-form by mechanical forming in which the pre-form is created with a die and punch. Thereafter the pre-form is subjected to gas pressure in a forming cavity to complete formation of the part. A metallic gasket is provided to ensure that no pressurized gas escapes from the forming cavity.

Abstract: A method and apparatus for forming a sheet of ductile material by superplastic forming is disclosed. The method is directed to first creating a pre-form by mechanical forming in which the pre-form is created with a die and punch. Thereafter the pre-form is subjected to gas pressure in a forming cavity to complete formation of the part. A metallic gasket is provided to ensure that no pressurized gas escapes from the forming cavity.

Abstract: A method for hemming an inner panel and an outer sheet metal panel together. The inner panel has an outwardly extending perimeter flange comprising an end surface, an inboard surface, and a beveled surface located between the end surface and the inboard surface. The outer sheet metal panel has a peripheral edge comprising a bend portion, an intermediate portion, and an end portion. The method provides a reduced radius hem by providing the beveled surface, assembling the inner and outer panels together, prehemming the peripheral edge to a spaced relationship relative to the beveled surface, and hemming the peripheral edge of the outer panel into engagement with the perimeter flange of the inner panel.

Abstract: A superplastic forming tool for forming a workpiece to make a part. The forming tool includes a forming die having first and second die members. At least one of the die members having a cavity including a forming surface and a plenum. A plurality of passageways extend between the plenum and the cavity. The passageways allow passage of fluid between the cavity and the plenum.

Abstract: A system and method for superplastic forming a workpiece. The system includes a superplastic forming cell formed of a plurality of individual stations or modules, each one performing a specific manufacturing step or process on the workpiece. Individual stations include a preheat station, a forming station, a cooling station, a cleaning station and a trimming station. These stations work in conjunction with one another to reduce superplastic forming cycle times and correspondingly increased production times when manufacturing a workpiece using a superplastic forming process.