Patents by Inventor Peter Frommolt

Peter Frommolt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130023420
    Abstract: The present invention relates to a combination of cell lines as well as a method of selecting (a) cell(s), (a) tissue(s) or (a) cell culture(s) with susceptibility to an HSP90 inhibitor anti-tumor agent. Also a method for determining the responsiveness of a mammalian tumor cell or cancer cell or collection of cells or cell lines to treatment with a drug such as an HSP90 inhibitor anti-tumor agent is described herein.
    Type: Application
    Filed: February 14, 2012
    Publication date: January 24, 2013
    Inventors: Roman Thomas, Kathrin Maring, Thomas Zander, Peter Frommolt, Kwok-kin Wong
  • Publication number: 20110319415
    Abstract: The present invention relates to a method of selecting (a) cell(s), (a) tissue(s) or (a) cell culture(s) with susceptibility to an HSP90 inhibitor. Also a method for determining the responsiveness of a mammalian tumor cell or cancer cell to treatment with an HSP90 inhibitor is described herein. In particular, the present invention provides for an in vitro method for the identification of a responder for or a patient sensitive to an HSP90 inhibitor and uses of an oligo- or polynucleotide capable of detecting (an) activating mutation(s) in the KRAS gene are provided. The present invention also relates to a method of monitoring the efficacy of a treatment of a cancer characterized by the presence of at least one activating mutation in the KRAS gene, and. optionally, in the EGFR gene and/or the BRAF gene. In addition, a method of predicting the efficacy of a cancer treatment is described, in particular in a cancer that is characterized by the presence of at least one activating mutation in the KRAS gene. and.
    Type: Application
    Filed: August 17, 2009
    Publication date: December 29, 2011
    Applicants: Universit+e,uml a+ee t zu K+e,uml o+ee ln, Max-Planck-Gesellschaft zur F+e,uml o+ee rderung der Wissens
    Inventors: Roman Thomas, Kathrin Maring, Thomas Zander, Peter Frommolt, Kwok-kin Wong