Patents by Inventor Peter G. M. Wuts

Peter G. M. Wuts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS
    Publication number: 20130018018
    Abstract: Compounds and compositions are provided for treatment, prevention, or amelioration of a variety of medical disorders associated with viral infections and/or cell proliferation. The compounds provided herein are nucleoside phosphonates and esters thereof.
    Type: Application
    Filed: August 27, 2010
    Publication date: January 17, 2013
    Applicant: Epiphany Biosciences ,Inc.
    Inventors: Steven Dong, Peter G.M. Wuts
  • Process to prepare taxol
    Patent number: 6307064
    Abstract: The present invention includes processes to prepare commercially important taxols (X) from substituted amino-3-phenyl (2R,3S) isoserinates (II). In addition processes to prepare the substituted amino-3-phenyl (2R,3S) isoserinates (II) as well as its precursor are set forth.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: October 23, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Peter G. M. Wuts, Robert C. Kelly
  • Process to prepare taxol
    Patent number: 6177573
    Abstract: The invention is an oxazolidine ester of silylated baccatin III of formula (VII) which is a useful intermediate to produce pharmaceutically useful anti-cancer compounds.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: January 23, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Peter G. M. Wuts, Robert C. Kelly
  • Process to prepare taxol
    Patent number: 6057452
    Abstract: The invention is novel intermediates useful in producing taxol.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: May 2, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Peter G. M. Wuts, Robert C. Kelly
  • Antineoplastic use and pharmaceutical compositions containing them
    Patent number: 5821363
    Abstract: This invention provides 7-deoxy-.DELTA..sup.12,13 -iso-taxol of formula (I) which are useful for the treatment of the same cancers for which taxol has been shown active.
    Type: Grant
    Filed: July 23, 1996
    Date of Patent: October 13, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Nancy A. Wicnienski, Robert C. Kelly, Peter G. M. Wuts
  • Intermediate used for the preparation of deferoxamine
    Patent number: 5430176
    Abstract: A method for preparing deferoxamine and a composition of Formula IX--Ph--CH.sub.2 --O--C(O)--NH--(CH.sub.2).sub.4 --CH.dbd.NORwherein X is a C.sub.1 -C.sub.4 alkyl, --O(C.sub.1 -C.sub.4 alkyl), a halogen or hydrogen,; R is X--Ph--CH.sub.2 -- or hydrogen for preparing deferoxamine. In one embodiment X and R are hydrogen. The intermediate, Formula I, has the advantage of being prepared in fewer and more efficient steps from readily available materials than conventional means for preparing deferoxamine.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: July 4, 1995
    Assignee: The Upjohn Company
    Inventor: Peter G. M. Wuts
  • Dipeptide hydroxy ethylene isostere synthesis and intermediates therefor
    Patent number: 5175298
    Abstract: The present invention provides processes and intermediates for one preparation of the hydroxy ethylene isostere dipeptide of leu-val which is itself useful in the preparation of renin inhibitory peptides. The process employs certain novel oxazolidenes.
    Type: Grant
    Filed: December 11, 1990
    Date of Patent: December 29, 1992
    Assignee: The Upjohn Company
    Inventor: Peter G. M. Wuts
  • Intermediate for the preparation of deferoxamine
    Patent number: 5011976
    Abstract: An intermediate useful in the preparation of deferoxamine having Formula IX--Ph--CH.sub.2 --O--C(O)--NH--(CH.sub.2).sub.4 CH.dbd.NORwherein X is a C.sub.1 -C.sub.4 alkyl, --O(C.sub.1 -C.sub.4 alkyl), a halogen or hydrogen; R is X--Ph--CH.sub.2 -- or hydrogen. In one embodiment X and R are hydrogen. The intermediate has the advantage of being prepared in fewer and more efficient steps from readily available materials than conventional means for preparing deferoxamine.
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: April 30, 1991
    Assignee: The Upjohn Company
    Inventor: Peter G. M. Wuts
  • Flurbiprofen intermediate
    Patent number: 4885404
    Abstract: Disclosed is a process for the production of acids of the formula ##STR1## wherein R is 2-fluoro-4-(1,1'-biphenyl), 4-(2-methylpropyl)phenyl, 6-methoxy-2-napthyl, 3-benzophenyl, 4-(2-thienylcarbonyl)-phenyl or 7-chlorocarbazole-3-yl which comprises contacting an organometallic compound of the formula R--M--R.sub.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: December 5, 1989
    Assignee: The Upjohn Company
    Inventor: Peter G. M. Wuts