Patents by Inventor Peter G. Milner

Peter G. Milner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for using A.sub.1 adenosine receptor agonists
    Patent number: 5998387
    Abstract: Adenosine and xanthine deriviatives, and compositions comprising those compounds, are potent selective agonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.
    Type: Grant
    Filed: April 6, 1998
    Date of Patent: December 7, 1999
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Luiz Belardinelli, Ray Olsson, Stephen Baker, Peter J. Scammells, Peter G. Milner, Jurg R. Pfister
  • N.sup.6 -(epoxynorborn-2-yl) adenosines as A.sub.1 adenosine receptor agonists
    Patent number: 5736528
    Abstract: N.sup.6 -(epoxynorborn-2-yl)adenosines are Al adenosine receptor agonists that are useful for controlling atrial fibrillation, ventricular rate in atrial flutter, supraventricular tachyarrhythmia, inhibiting A--V- nodal transmission in supraventricular tachycardia, and for normalizing ventricular rhythm and hemodynamics.
    Type: Grant
    Filed: December 29, 1995
    Date of Patent: April 7, 1998
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Luiz Belardinelli, Ray Olsson, Stephen Baker, Peter J. Scammells, Peter G. Milner, Jurg R. Pfister
  • A1 adenosine receptor agonists and antagonists
    Patent number: 5668139
    Abstract: Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 16, 1997
    Assignee: University of Flordia Research Foundation, Inc.
    Inventors: Luiz Belardinelli, Ray Olsson, Stephen Baker, Peter J. Scammells, Peter G. Milner, Jurg R. Pfister, George F. Schreiner
  • Xanthine epoxides as A.sub.1 adenosine receptor agonists and antagonists
    Patent number: 5631260
    Abstract: Xanthine derivatives, and compositions comprising those compounds, are potent selective antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias. The compounds, specifically, are C-8 epoxide derivatives of xanthine having the general formulae of: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different, and can be H or an alkyl group of 1-4 carbons, and n=0-4; and ##STR2## wherein R.sub.1 and R.sub.2 are the same or different, and can be H or an alkyl group of 1-4 carbons, R.sub.3 is either O or (CH.sub.2).sub.1-4, and n=0-4.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: May 20, 1997
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Luiz Belardinelli, Ray Olsson, Stephen Baker, Peter J. Scammells, Peter G. Milner, J urg R. Pfister, George F. Schreiner