Abstract: Exemplary imaging apparatuses are described. Various embodiments of the imaging apparatuses may implement optical coherence tomography (OCT) and/or optical frequency domain imaging (OFDI) tissue imaging technologies, with the capability to perform tissue retrieval at the same time. Furthermore, the imaging apparatuses may include a rotatable imaging element to scan a bodily lumen, such as the bile duct. The imaging element may be housed within a cylindrical window. Still further, the imaging apparatuses may include an ancillary channel. The ancillary channel may provide access to the tissue in the bile duct, or other bodily lumen.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. Wire having enhanced radiopacity is included in the filter to provide visualization under fluoroscopy.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. In several embodiments, the guidewire distal to the filter has a fixed tip length. Other embodiments of the invention include a mechanism for damping longitudinal movement between the distal and proximal ends of the filter.

Abstract: The present invention is a temporary device for capturing and removing embolic material during interventional procedures, such as angioplasty or stent deployment. A self-closing, tubular capture element, which may be either a filter or an occluder, is mounted near the distal end of a guidewire. The guidewire is capable of guiding a therapeutic catheter. Relative displacement of the capture element ends causes transformation of the capture element between a closed configuration and a deployed configuration that spans the vessel to be treated. A latch fixed to the guidewire temporarily retains the capture element in the deployed configuration. A first hollow rod slides over the guidewire to deploy the capture element and engage the capture element proximal end with the latch. A second hollow rod slides over the guidewire to release the latch and close the capture element.

Abstract: A guidewire apparatus for use during percutaneous catheter interventions, such as angioplasty or stent deployment. A protection element comprising a filter or an occluder is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. The guidewire apparatus comprises a hollow shaft movably disposed about a core wire and, optionally, a slippery liner interfitted there between. The shaft and core wire control relative displacement of the ends of the protection element, causing transformation of the protection element between a deployed configuration and a collapsed configuration.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. Wire having enhanced radiopacity is included in the filter to provide visualization under fluoroscopy.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. In several embodiments, the guidewire distal to the filter has a fixed tip length. Other embodiments of the invention include a mechanism for damping longitudinal movement between the distal and proximal ends of the filter.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. In several embodiments, the guidewire distal to the filter has a fixed tip length. Other embodiments of the invention include a mechanism for damping longitudinal movement between the distal and proximal ends of the filter.

Abstract: A guidewire apparatus for use during percutaneous catheter interventions, such as angioplasty or stent deployment. A protection element comprising a filter or an occluder is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. The guidewire apparatus comprises a hollow shaft movably disposed about a core wire and, optionally, a slippery liner interfitted there between. The shaft and core wire control relative displacement of the ends of the protection element, causing transformation of the protection element between a deployed configuration and a collapsed configuration.

Abstract: A guide wire apparatus for prevention of distal atheroembolization during percutaneous catheter intervention procedures, such as angioplasty or stent deployment. An expandable protection element, such as a self-expanding or self-collapsing filter or occluder, is mountable adjacent the distal end of a core wire, which can guide a therapeutic catheter. Relative displacement of the ends of the protection element causes transformation of the protection element between a closed configuration and an expanded configuration that spans the vessel to be treated. An operator rod, which may be a hollow rod or an interventional catheter, may be slidably disposed over the core wire to engage with and either push or pull the proximal end of the protection element to cause transformation thereof.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. Wire having enhanced radiopacity is included in the filter to provide visualization under fluoroscopy.

Abstract: The present invention is a temporary device for capturing and removing embolic material during interventional procedures, such as angioplasty or stent deployment. A self-closing, tubular capture element, which may be either a filter or an occluder, is mounted near the distal end of a guidewire. The guidewire is capable of guiding a therapeutic catheter. Relative displacement of the capture element ends causes transformation of the capture element between a closed configuration and a deployed configuration that spans the vessel to be treated. A latch fixed to the guidewire temporarily retains the capture element in the deployed configuration. A first hollow rod slides over the guidewire to deploy the capture element and engage the capture element proximal end with the latch. A second hollow rod slides over the guidewire to release the latch and close the capture element.

Abstract: The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. In several embodiments, the guidewire distal to the filter has a fixed tip length. Other embodiments of the invention include a mechanism for damping longitudinal movement between the distal and proximal ends of the filter.

Abstract: A medical catheter including a continuous liner defining a guidewire lumen. The liner has a constant inner diameter and a constant outer diameter. A continuous layer is braided over the liner and encapsulated between the liner and a bump layer. The bump layer has a proximal segment, and a bump section. The bump section has a transition zone at the proximal end of the bump section. The proximal segment has a distal end affixed to the proximal end of the bump section. The proximal segment of the bump layer has an outer diameter which is less than the outer diameter of the bump section of the bump layer. The transition zone has an outer diameter which smoothly transitions from the outer diameter of the distal end of the proximal segment of the bump layer to the larger outer diameter at the distal end of the transition zone. The bump layer is encapsulated between the outer jacket layer and the braided layer.