Patents by Inventor Peter Galen
Peter Galen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11971384Abstract: Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or “bound complex” with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.Type: GrantFiled: October 18, 2021Date of Patent: April 30, 2024Assignee: Hemex Health, Inc.Inventors: Peter Galen, Ariane Elizabeth Erickson, David Richard Bell, Matthew Christian Lind, Tyler Witte, Umut Atakan Gurkan
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Publication number: 20230400431Abstract: A diagnostic system that includes a cartridge and a reader is discussed herein. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease, or infection of the patient.Type: ApplicationFiled: August 28, 2023Publication date: December 14, 2023Inventors: Peter Galen, Umut Atakan Gurkan, Muhammad Noman Hasan, James Daren Bledsoe, Tyler Witte
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Publication number: 20230309874Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: ApplicationFiled: June 6, 2023Publication date: October 5, 2023Inventors: Peter GALEN, Umut Atakan GURKAN, Arwa FRAIWAN, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
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Patent number: 11740203Abstract: A diagnostic system that includes a cartridge and a reader is discussed herein. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease, or infection of the patient.Type: GrantFiled: June 25, 2020Date of Patent: August 29, 2023Assignee: Hemex Health, Inc.Inventors: Peter Galen, Umut Atakan Gurkan, Muhammad Noman Hasan, James Daren Bledsoe, Tyler Witte
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Patent number: 11701039Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: GrantFiled: July 15, 2019Date of Patent: July 18, 2023Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, Umut Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
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Patent number: 11656220Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.Type: GrantFiled: August 21, 2020Date of Patent: May 23, 2023Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umut Atakan Gurkan
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Publication number: 20230111151Abstract: A diagnostic system detects and/or measures hemoglobin variants in blood of subject, such as HbA1c, to determine blood glucose concentration in the subject.Type: ApplicationFiled: July 5, 2022Publication date: April 13, 2023Inventors: Umut Gurkan, Arwa Fraiwan, Peter Galen
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Patent number: 11376590Abstract: A diagnostic system detects and/or measures hemoglobin variants in blood of subject, such as HbA1c, to determine blood glucose concentration in the subject.Type: GrantFiled: February 3, 2020Date of Patent: July 5, 2022Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Umut Gurkan, Arwa Fraiwan, Peter Galen
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Publication number: 20220146491Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient. For example, the data collection and analysis can differentiate between two or more species capable of causing or actually causing a parasitic infection.Type: ApplicationFiled: April 10, 2020Publication date: May 12, 2022Inventors: Peter GALEN, James Daren Bledsoe, Robert J. Deissler, D'Arbra Blankenship, Brian T. Grimberg
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Patent number: 11255815Abstract: Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or “bound complex” with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.Type: GrantFiled: April 15, 2021Date of Patent: February 22, 2022Assignee: Hemex Health, Inc.Inventors: Peter Galen, Ariane Elizabeth Erickson, David Richard Bell, Matthew Christian Lind, Tyler Witte, Umut Atakan Gurkan
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Publication number: 20220042946Abstract: Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or “bound complex” with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.Type: ApplicationFiled: October 18, 2021Publication date: February 10, 2022Inventors: Peter GALEN, Ariane Elizabeth ERICKSON, David Richard BELL, Matthew Christian LIND, Tyler WITTE, Umut Atakan GURKAN
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Publication number: 20210376597Abstract: A circuit for preventing sparks. The circuit having a power storage component having a first power storage end and a second power storage end; a power source electrically connected to the power storage component, the power source having a first power source end and a second power source end; a first current directional component electrically connected to the power storage component and having a first current direction; a first power absorption component electrically connected to the power storage component and having a current direction, the first current directional component and the first power absorption component being electrically connected to the power storage component in parallel; and at least one switch electrically connected to the power storage component.Type: ApplicationFiled: December 20, 2019Publication date: December 2, 2021Inventors: Peter Galens, David J. Trapasso
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Publication number: 20210341360Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient. Processing can include external sonication and conjugating non-magnetic target material with magnetic nanoparticles and non-magnetic solids.Type: ApplicationFiled: October 17, 2019Publication date: November 4, 2021Inventors: Peter GALEN, Oren BERNSTEIN, James Daren BLEDSOE, Daniel E. GRUPP, Joshua King HOYT, David John SAYLER, James THORNE, Jered WIKANDER, Tyler WITTE
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Publication number: 20210325341Abstract: Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or “bound complex” with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.Type: ApplicationFiled: April 15, 2021Publication date: October 21, 2021Inventors: Peter GALEN, Ariane Elizabeth ERICKSON, David Richard BELL, Matthew Christian LIND, Tyler WITTE, Umut Atakan GURKAN
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Publication number: 20210311016Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Inventors: Peter Galen, James Daren Bledsoe, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss, Brian T. Grimberg
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Publication number: 20210292701Abstract: External sonication, which is a technique by which ultrasonic energy is applied externally to a cartridge containing the sample, is contemplated herein. External sonication can be performed by a sonicator external to a sample contained within a cartridge. The cartridge can include sonication particles to enhance sonication or cavitation within the sample. A sonication algorithm can also be used to increase sonication efficiency.Type: ApplicationFiled: June 8, 2021Publication date: September 23, 2021Inventors: Peter Galen, James Daren Bledsoe, Jered Wikander, Steven M. Goss
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Patent number: 11061014Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.Type: GrantFiled: June 25, 2020Date of Patent: July 13, 2021Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, James Daren Bledsoe, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss, Brian T. Grimberg
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Patent number: 11053473Abstract: External sonication, which is a technique by which ultrasonic energy is applied externally to a cartridge containing the sample, is contemplated herein. External sonication can be performed by a sonicator external to a sample contained within a cartridge. The cartridge can include sonication particles to enhance sonication or cavitation within the sample. A sonication algorithm can also be used to increase sonication efficiency.Type: GrantFiled: June 25, 2020Date of Patent: July 6, 2021Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, James Daren Bledsoe, Jered Wikander, Steven M. Goss
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Publication number: 20200408735Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.Type: ApplicationFiled: June 25, 2020Publication date: December 31, 2020Inventors: Peter Galen, James Daren Bledsoe, Brian T. Grimberg, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss
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Patent number: D968641Type: GrantFiled: September 30, 2020Date of Patent: November 1, 2022Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, James Daren Bledsoe, Jered Wikander, James Thorne, Joshua King Hoyt