Patents by Inventor Peter Gascoyne
Peter Gascoyne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9395331Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: July 22, 2015Date of Patent: July 19, 2016Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Publication number: 20150336111Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 22, 2015Publication date: November 26, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Publication number: 20150321201Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 22, 2015Publication date: November 12, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Publication number: 20150323497Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 22, 2015Publication date: November 12, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Publication number: 20150027895Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: August 5, 2014Publication date: January 29, 2015Inventors: Frederick F. BECKER, Peter GASCOYNE, Xiaobo WANG, Jody Valentine VYKOUKAL, Giovanni De GASPERIS
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Patent number: 8834810Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: July 10, 2012Date of Patent: September 16, 2014Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Publication number: 20130118903Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: July 10, 2012Publication date: May 16, 2013Inventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Patent number: 8216513Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: November 20, 2009Date of Patent: July 10, 2012Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F Becker, Peter Gascoyne, Xiaobo Wang, Jody Vykoukal, Giovanni De Gasperis
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Publication number: 20100084273Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: November 20, 2009Publication date: April 8, 2010Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Patent number: 7641779Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: May 23, 2005Date of Patent: January 5, 2010Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Valentine Vykoukal, Giovanni De Gasperis
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Publication number: 20060254920Abstract: Methods and apparatus for preparing a smear for cytopathology or other analysis. In a representative embodiment, cells of a sample are subjected to a dielectrophoretic force to segregate the cells into two or more zones of a surface. The particles are attached to the surface, thereby defining a “segregated smear.” The segregated smear is then fixed and stained for cytopathology analysis.Type: ApplicationFiled: July 24, 2006Publication date: November 16, 2006Inventors: Peter Gascoyne, Jody Vykoukal, Chandra Das, Frederick Becker
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Publication number: 20060114296Abstract: Disclosed are apparatuses, systems, and methods for programmable fluidic processors. In one embodiment, the invention involves manipulating droplets across a reaction surface of the processor substantially contact-free of any surfaces. The reaction surface and the electrodes of the processor may include a coating repelling the droplets. Further, the present invention provides for a suitable suspending medium for repelling droplets away from fixed surfaces.Type: ApplicationFiled: May 27, 2005Publication date: June 1, 2006Inventors: Peter Gascoyne, Jody Vykoukal, Jon Schwartz
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Publication number: 20060070879Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: ApplicationFiled: May 23, 2005Publication date: April 6, 2006Inventors: Frederick Becker, Peter Gascoyne, Xiaobo Wang, Jody Vykoukal, Giovanni De Gasperis
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Patent number: 6977033Abstract: A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.Type: GrantFiled: July 10, 2001Date of Patent: December 20, 2005Assignee: Board of Regents, The University of Texas SystemInventors: Frederick F. Becker, Peter Gascoyne, Xiaobo Wang, Jody Vykoukal, Giovanni De Gasperis
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Patent number: 6893547Abstract: Methods and apparatuses for metered injection of a fluid packet. A vessel containing a fluid is pressurized to a pressure less than or equal to a hold-off pressure. The fluid is subjected to an extraction force to form the fluid packet and extract the fluid packet from the vessel onto a surface.Type: GrantFiled: June 14, 2001Date of Patent: May 17, 2005Assignee: Board of Regents, The University of Texas SystemInventors: Peter Gascoyne, Jody V. Vykoukal, Jon Schwartz, Frederick F. Becker
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Publication number: 20050072677Abstract: Methods and apparatuses for particle focusing. Particles are focused within a fluid-flow channel using dielectrophoretic forces from electrodes disposed within the fluid-flow channel, and the focused particles can be detected with an optical detector.Type: ApplicationFiled: February 18, 2004Publication date: April 7, 2005Inventors: Peter Gascoyne, Jody Vykoukal
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Patent number: 6866762Abstract: A dielectric gate and related systems and methods for controlling fluid flow. A dielectric gate includes one or more electrodes coupled between an inlet fluid pathway and an outlet fluid pathway. The electrodes are configured to draw fluid from the inlet fluid pathway to the outlet fluid pathway in a precise manner by using dielectric forces arising from electrical signals applied to the electrodes.Type: GrantFiled: December 20, 2001Date of Patent: March 15, 2005Assignee: Board of Regents, University of Texas SystemInventors: Peter Gascoyne, Jon Schwartz, Jody V. Vykoukal, Frederick F. Becker
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Patent number: 6790330Abstract: Systems, apparatuses and methods for cell isolation and analysis. Cells are introduced into a dielectrophoretic prefilter including one or more trapping electrodes configured to trap at least a portion of the cells with a dielectrophoretic force. The cells trapped from the prefilter are directed into a dielectrophoretic field-flow fractionation separator coupled to the prefilter. The cells are discriminated by balancing a dielectrophoretic force (and optionally a magnetophoretic force) with a gravitational force to displace the cells to positions within a velocity profile in the separator. At least a portion of the cells are trapped as a function of the cells' time of emergence from the separator with two or more spiral electrode segments coupled to the separator.Type: GrantFiled: June 14, 2001Date of Patent: September 14, 2004Assignee: Board of Regents, The University of Texas SystemInventors: Peter Gascoyne, Jody V. Vykoukal, Frederick F. Becker
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Patent number: 6703819Abstract: Apparatuses and methods for analyzing particles using an impedance sensor. A flow-through impedance sensor may use two in-line electrodes driven in counter phase. A common sensor electrode may be used to, for example, detect impedance and determine trajectories through the sensor area. The sensor may be used in a wide variety of applications, including but not limited to use with microfluidic devices for determining particle characteristics such as position, velocity, size, and concentration as well as detection of bacterial spores and other biological agents of potential use in warfare and bio-terrorism.Type: GrantFiled: December 3, 2001Date of Patent: March 9, 2004Assignee: Board of Regents, The University of Texas SystemInventors: Peter Gascoyne, Tom Anderson, Jody Vykoukal, Frederick Becker
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Publication number: 20030170698Abstract: Devices, systems, and methods for an oligonucleotide synthesis engine. In on embodiment, the invention involves a microfluidic device including: an oligonucleotide synthesis subunit including a reaction surface and means for generating a manipulation force and routing for packet delivery; an analysis or diagnostic subunit; and a control subunit including a program to direct oligonucleotide synthesis. In another embodiment, the invention involves a method for analyzing a sample. An oligonucleotide is synthesized in a solid-phase oligonucleotide synthesis subunit, wherein the subunit includes a reaction surface and means for generating a manipulation force and routing for packet delivery. The synthesis is controlled with a control subunit, wherein the control subunit is programmed for the automatic synthesis of oligonucleotides. The sample is analyzed in an analysis or diagnostic subunit.Type: ApplicationFiled: January 3, 2003Publication date: September 11, 2003Inventors: Peter Gascoyne, Jody V. Vykoukal, Jon Schwartz, Frederick F. Becker