Abstract: Disclosed are recombinant insect ferritin nanoparticles that can be used to display two different trimeric antigens at an equal ratio. Also disclosed are nucleic acids encoding the recombinant insect ferritin nanoparticles and methods of producing the recombinant insect ferritin nanoparticles. Methods for eliciting an immune response in a subject are also provided.

Abstract: Provided herein are IL-2 muteins that bind to IL-2 receptor subunit but do not have measurable binding to IL-2 receptor subunit. Also provided are compositions, kits, methods, and uses involving such IL-2 muteins.

Abstract: A system and method of searching for real estate. A server is communicatively connected to a database comprised of real estate records. One or more client devices communicatively connected to the server receive a defined non-contiguous geographic search area and attribute criteria values for attributes of the sought real estate and the client devices transmit the defined non-contiguous geographic search area and attribute criteria values to the server. The server calculates minimum bounding rectangles corresponding to the non-contiguous geographic search area, queries the database of real estate using the minimum bounding rectangles and attribute criteria values to generate a first set of returned records, compares the first set of returned records against the defined non-contiguous search area to generate a second set of returned records that is a subset of the first set of returned records, and transmits the second set of returned records to the client device.

Abstract: This invention relates to methods and devices for propulsion through a fluid, in particular at low Reynolds number. We describe a method of propelling one of a magnetic device and a fluid relative to the other, the magnetic device comprising a pair of magnetic moments linked by an elastic coupling element, one of said moments having a greater resistance to a change in orientation due to an external applied magnetic field than the other, the method comprising applying an elliptical or ellipsoidal rotating magnetic field to the device to cause a change in mutual attraction or repulsion between said magnetic moments to thereby change a physical configuration of said device, propelling said device relative to said fluid.

Abstract: This invention relates to methods and devices for propulsion through a fluid, in particular at low Reynolds number. We describe a method of propelling one of a magnetic device and a fluid relative to the other, the magnetic device comprising a pair of magnetic moments linked by an elastic coupling element, one of said moments having a greater resistance to a change in orientation due to an external applied magnetic field than the other, the method comprising applying an elliptical or ellipsoidal rotating magnetic field to the device to cause a change in mutual attraction or repulsion between said magnetic moments to thereby change a physical configuration of said device, propelling said device relative to said fluid.