Patents by Inventor Peter Glunz

Peter Glunz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic factor VIIa inhibitors
    Patent number: 9174974
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: November 3, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiaojun Zhang, Peter Glunz, Eldon Scott Priestley, James A. Johnson, Nicholas Ronald Wurtz, Vladimir Ladziata
  • MACROCYCLIC FACTOR VIIA INHIBITORS
    Publication number: 20150148313
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
    Type: Application
    Filed: June 5, 2013
    Publication date: May 28, 2015
    Inventors: Xiaojun Zhang, Peter Glunz, Eldon Scott Priestley, James A. Johnson, Nicholas Ronald Wurtz, Vladimir Ladziata
  • Glycopeptide conjugates and uses thereof
    Patent number: 7550146
    Abstract: The present invention provides novel glycoconjugates such as glycopeptides, as well as convergent methods for the synthesis thereof. An exemplary preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the glycoconjugates of the invention.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: June 23, 2009
    Assignee: Sloan-Kettering Institute For Cancer Research
    Inventors: Samuel J. Danishefsky, Dalibor Sames, Samuel Hintermann, Peter Glunz, Govindaswami Ragupathi, Philip O. Livingston, Kenneth O. Lloyd, Valery Kudryashov
  • MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS
    Publication number: 20070208054
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, L, M, W, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of the serine protease coagulation factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 21, 2006
    Publication date: September 6, 2007
    Inventors: Eldon Priestley, Daniel Cheney, Nicholas Wurtz, Peter Glunz
  • ?-O-linked glycoconjugates, methods of preparation and uses thereof
    Patent number: 7160856
    Abstract: The present invention provides novel ?-O-linked glycoconjugates such as ?-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the ?-O-linked glycoconjugates.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: January 9, 2007
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Dalibor Sames, Samuel Hintermann, Xiao Tao Chen, Jacob B. Schwarz, Peter Glunz, Govindaswami Ragupathi, Philip O. Livingston, Scott Kuduk, Lawrence Williams
  • Heterocyclic compounds as inhibitors of factor VIIa
    Publication number: 20060211720
    Abstract: The present invention relates generally to compounds that inhibit serine proteases. In particular it is directed to novel heterocyclic compounds, or a stereoisomer or pharmaceutically acceptable salt, solvate, or prodrug form thereof, which are useful as selective inhibitors of serine protease enzymes of the coagulation cascade; for example thrombin, factor VIIa, factor Xa, factor XIa, factor IXa, and/or plasma kallikrein. In particular, it relates to compounds that are factor VIIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.
    Type: Application
    Filed: December 7, 2005
    Publication date: September 21, 2006
    Inventors: Peter Glunz, Nicolas Wurtz, Xuhong Cheng
  • Glycopeptide conjugates and uses thereof
    Publication number: 20050222398
    Abstract: The present invention provides novel ?-O-linked glycoconjugates such as ?-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the ?-O-linked glycoconjugates.
    Type: Application
    Filed: July 23, 2004
    Publication date: October 6, 2005
    Inventors: Samuel Danishefsky, Dalibor Sames, Samuel Hintermann, Peter Glunz, Govindaswami Ragupathi, Philip Livingston, Kenneth Lloyd, Valery Kudryashov
  • Cycloalkyl heterocycles for treating Hepatitis C virus
    Publication number: 20050075376
    Abstract: Compounds of Formula I are disclosed which inhibit hepatitis C NS5B RNA-dependent RNA polymerase and are useful for treating hepatitis C. Compositions and methods of using these compounds are also disclosed.
    Type: Application
    Filed: August 19, 2004
    Publication date: April 7, 2005
    Inventors: Peter Glunz, Brent Douty, Scott Martin, Jeffrey Romine
  • Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof
    Publication number: 20040102607
    Abstract: The present invention provides novel &agr;-O-linked glycoconjugates such as &agr;-O-linked glycopeptides, as well as convergent methods for the synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the &agr;-O-linked glycoconjugates.
    Type: Application
    Filed: June 19, 2003
    Publication date: May 27, 2004
    Inventors: Samuel J. Danishefsky, Dalibor Sames, Samuel Hintermann, Xiao Tao Chen, Jacob B. Schwarz, Peter Glunz, Govindaswami Ragupathi, Philip O. Livingston, Scott Kuduk, Kenneth O. Lloyd, Lawrence Williams, Valery Kudryashov
  • &agr;-O-linked glycoconjugates, methods of preparation and uses thereof
    Patent number: 6660714
    Abstract: The present invention provides novel &agr;-O-linked glycoconjugates such as &agr;-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the &agr;-O-linked glycoconjugates.
    Type: Grant
    Filed: March 25, 1998
    Date of Patent: December 9, 2003
    Assignee: Sloan Kettering Institute for Cancer Research
    Inventors: Samuel J. Danishefsky, Dalibor Sames, Samuel Hintermann, Xiao-Tao Chen, Jacob B. Schwartz, Peter Glunz, Govindaswami Ragupathi, Philip O. Livingston, Scott Kuduk, Lawrence Williams
  • Alpha-o-linked glycoconjugates, methods of preparation and uses thereof
    Publication number: 20030083235
    Abstract: The present invention provides novel &agr;-O-linked glycoconjugates such as &agr;-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the &agr;-O-linked glycoconjugates.
    Type: Application
    Filed: July 25, 2002
    Publication date: May 1, 2003
    Inventors: Samuel J. Danishefsky, Dalibor Sames, Samuel Hintermann, Xiao Tao Chen, Jacob B. Schwarz, Peter Glunz, Govindaswami Ragupathi, Philip O. Livingston, Scott Kuduk, Lawrence Williams