Abstract: The present application relates to indolizine-based compounds of the general formula (I) and aza-analogs thereof, which have medical utility, for example as antipsychotics.

Abstract: The invention relates to compounds according to general formula (1) and/or their enantiomers, diastereomers, and their pharmaceutically compatible salts, and their use to manufacture a medication as well as medications. The compounds are suited for treatment of diseases connected with misfolded proteins.

Abstract: A method for operating cooperating, differing devices, particularly of a plant, with different controls controlling the control sequences and in particular with different control cycles, is characterized in that the clocks (IPOi) of the different controls (3.1, 3.2, 3.3) are interpolated on a common system clock (tTick) and that the control sequences are synchronized. An apparatus suitable for performing the inventive method correspondingly has at least one common interpolating device (5.3) for the controls (3.1, 3.2, 3.3) for interpolating the cycles (IPOi) of the different controls (3.1, 3.2, 3.3) on a common system clock (tTick) and at least one synchronizing device (5) for synchronizing the control sequences.

Abstract: The invention relates to compounds according to general formula (1) and/or their enantiomers, diastereomers as well as their pharmaceutically compatible salts, and to the use thereof for producing a medicament suited for treating diseases associated with misfolded proteins.

Abstract: An imaging device with a radiographic source and with at least one image receiver, with an imaging detector able to be assigned to the image receiver or to each image receiver and with the image receiver or each image receiver including a sensor for registration of the imaging detector, with a signal output of the sensor being connected directly in a circuit to a signal input of the radiographic source.

Abstract: The invention relates to annelated phenyl piperazine and phenyl diazepane carboxamides of general formula (I) containing oxygen. The compounds are suitable for medical use.

Abstract: The present invention concerns neuroreceptor-active carboxamide-substituted indolizine derivatives of general formula I wherein X represents a group of general formula X1

Abstract: The invention relates to azaindole derivatives of general formula (I), wherein X represents a group of general formula (X1). Said compounds have a therapeutic potential in the treatment of diseases that are accompanied by an impaired dopamine metabolism and/or abnormal serotonin-5-HT1a signal transmission.

Abstract: A method for machining workpieces by means of a multiaxial manipulator, such as an industrial robot, with a tool moved proportionally by a control unit of the manipulator and which can perform characteristic movements with several degrees of freedom is characterized in that the degrees of freedom of the tool are evaluated together with the degrees of freedom of axes of the manipulator in real time for moving a tool tip (TCP) in accordance with a predetermined, continuous machining path or a portionwise continuous machining geometry (step function) and for determining a movement of the manipulator. The invention also proposes a device suitable for performing the aforementioned method, in which the tool and a tool tip, during workpiece machining, are movement-controllable by the manipulator control unit. In this way it is possible to drastically reduce the overall machining time.

Abstract: The invention relates to neuroreceptor active N-[(4-phenyl-1-piperazinyl)alkyl]-substituted heteroarene carboxamide of general formula (I) and to structure analogous 2-ferrocenyl compounds of general formula (II) and the utilization thereof for the treatment of CNS diseases, for example, schizophrenia, different forms of depression, neurodegenerative disorders, sexual dysfunctions, cocaine, alcohol, opiate and nicotine addiction, in addition to glaucoma, cognitive disorders, restless leg syndrome, hyperactivity syndrome (ADHS), hyperprolactinemia, hyperprolactinoma, locomotion disorders associated with Parkinson's disease, treatment of L-DOPA and neuroleptic-induced locomotion disorders, for example, akathisia, rigor, dystonia and dyskinesia, wherein the substituents are defined in the description.

Abstract: A method for machining workpieces by means of a multiaxial manipulator, such as an industrial robot, with a tool moved proportionally by a control unit of the manipulator and which can perform characteristic movements with several degrees of freedom is characterized in that the degrees of freedom of the tool are evaluated together with the degrees of freedom of axes of the manipulator in real time for moving a tool tip (TCP) in accordance with a predetermined, continuous machining path or a portionwise continuous machining geometry (step function) and for determining a movement of the manipulator. The invention also proposes a device suitable for performing the aforementioned method, in which the tool and a tool tip, during workpiece machining, are movement-controllable by the manipulator control unit. In this way it is possible to drastically reduce the overall machining time.

Abstract: New 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine and -1,4-benzoxazonine compounds of the formula ##STR1## have useful pharmaceutical properites. They are prepared from ketones of the formula ##STR2## via a lactone intermediate. In the formula, the various R substitutes are generally hydrogen or alkyl, with R.sup.4 also being halogen or alkoxy and R.sup.3 R.sup.3' also being phenyl. R.sup.1 may be joined with R.sup.5 /R.sup.5' in a 5- to 7-membered ring possibly interrupted by O, S, SO.sub.2 or amino. One of X and Y is CH.sub.2 ; the other is amino. The starting ketones also have pharmaceutical properties. The lactone intermediates are new compounds.