Patents by Inventor Peter Gordon Laughton

Peter Gordon Laughton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for measuring aromatase activity
    Patent number: 8334387
    Abstract: The present invention relates to compounds useful for measuring aromatase activity. The invention further provides methods for measuring aromatase activity and for screening test agents which modulate aromatase activity. A kit is also provided for use in such screening methods.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: December 18, 2012
    Assignee: GE Healthcare UK Limited
    Inventors: John Gerard Whateley, Rahman Aziz Ismail, Peter Gordon Laughton
  • METHOD FOR MEASURING AROMATASE ACTIVITY
    Publication number: 20110014641
    Abstract: The present invention relates to compounds useful for measuring aromatase activity. The invention further provides methods for measuring aromatase activity and for screening test agents which modulate aromatase activity. A kit is also provided for use in such screening methods.
    Type: Application
    Filed: September 28, 2010
    Publication date: January 20, 2011
    Applicant: GE HEALTHCARE UK LIMITED
    Inventors: JOHN GERARD WHATELEY, RAHMAN AZIZ ISMAIL, PETER GORDON LAUGHTON
  • Method for measuring aromatase activity
    Patent number: 7829714
    Abstract: The present invention relates to compounds useful for measuring aromatase activity. The invention further provides methods for measuring aromatase activity and for screening test agents which modulate aromatase activity. A kit is also provided for use in such screening methods.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: November 9, 2010
    Assignee: GE Healthcare Limited
    Inventors: John Gerard Whateley, Rahman Aziz Ismail, Peter Gordon Laughton
  • WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS
    Publication number: 20100249385
    Abstract: Disclosed are cyanine dyes that are useful for labelling and detecting biological and other materials. The dyes are of formula (I): in which at least one of groups R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 R11, R12, R13 and R14 is -L-M or -L-P, where L is a linking group, M is a target bonding group and P is a conjugated component, and at least one of groups R3, R4, R5, R6, R7, R8, R9 and R19 comprises fluorine. The use of cyanine dyes substituted by fluorine and having additional substitution with three or more sulphonic acid groups for labelling biological target molecules results in a labelled product in which there is reduced dye-dye aggregation and improved photostability, compared with cyanine dyes having no such substitutions.
    Type: Application
    Filed: June 8, 2010
    Publication date: September 30, 2010
    Applicant: GE HEALTHCARE UK LIMITED
    Inventors: MICHAEL EDWARD COOPER, NICHOLAS JOHN GARDNER, PETER GORDON LAUGHTON
  • Water-soluble fluoro-substituted cyanine dyes as reactive fluorescence labelling reagents
    Patent number: 7767829
    Abstract: Disclosed are cyanine dyes that are useful for labelling and detecting biological and other materials. The dyes are of formula (I): in which at least one of groups R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 R11, R12, R13 and R14 is -L-M or -L-P, where L is a linking group, M is a target bonding group and P is a conjugated component, and at least one of groups R3, R4, R5, R6, R7, R8, R9 and R10 comprises fluorine. The use of cyanine dyes substituted by fluorine and having additional substitution with three or more sulphonic acid groups for labelling biological target molecules results in a labelled product in which there is reduced dye-dye aggregation and improved photostability, compared with cyanine dyes having no such substitutions.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: August 3, 2010
    Assignee: GE Healthcare UK Limited
    Inventors: Michael Edward Cooper, Nicholas John Gardner, Peter Gordon Laughton