Abstract: Systems and methods are provided for controlled infusion, effusion, and/or perfusion of biological/biocompatible liquid to and from a body cavity of a subject, and for continuous control of body cavity parameters, for example in neuro-intensive care. Systems and methods may relate to estimating compliance and pressure/volume changes within a body cavity. A bio-liquid replacement system may include a sensor for continuously measuring at least one parameter associated with the cavity, a pump for infusing the liquid into and aspirating the liquid out of the cavity, a processing unit continuously calculating at least one physiological parameter based on the measured parameter, and defining a target parameter slightly offset from the physiological parameter, and a flow controller controlling said pump unit based on the target parameter and the induced offset such that continuous compensatory changes are induced in the liquid volume. The processing unit continuously estimates the body cavity compliance.

Abstract: An electromechanical pulse generator and a method of generating electrical pulses are disclosed. The electromechanical pulse generator comprises very few parts and includes an effective mechanism to prevent contact rebound. An upper, user-actuable and rotatable part has a surface with a plurality of projections. A lower part has an electrical conductor with a displaceable resilient contact portion biased against the projections and two electrical contacts positioned, in the plane of rotation, on either side of the displaceable contact portion.

Abstract: An electromechanical pulse generator and a method of generating electrical pulses are disclosed. The electromechanical pulse generator comprises very few parts and includes an effective mechanism to prevent contact rebound. An upper, user-actuable and rotatable part has a surface with a plurality of projections. A lower part has an electrical conductor with a displaceable resilient contact portion biased against the projections and two electrical contacts positioned, in the plane of rotation, on either side of the displaceable contact portion.