Abstract: A dosage of an active ingredient in a treatment that is being provided to or that is being considered for provision to a subject is identified. A level of local amyloid beta is predicted based on the dosage of the active ingredient. A severity of amyloid-related imaging abnormalities (ARIA) manifested as hyperintensities on T2-weighted fluid attenuated inversion recovery (FLAIR) images (ARIA-E) is predicted based on the predicted removal of local amyloid beta, where predicting severity of ARIA-E includes predicting an extent of vascular wall disturbance. A result corresponding to the predicted ARIA-E severity is output.

Abstract: A computer-implemented method for capturing system memory dumps includes receiving, by a diagnostic data component, an instruction to capture a system memory dump associated with a computer process being executed by a computing system comprising one or more processing units, the system memory dump comprising data from a plurality of memory locations associated with the computer process. In response to determining that the system memory dump satisfies a predetermined criterion, the diagnostic data component sends a request for a computing resource boost from the computing system. Further, in response to the request for the computing resource boost being granted, the diagnostic data component uses additional computing resources from the one or more processing units to store the data from the plurality of memory locations in the system memory dump and executing the backlogged operations that were halted due to the system memory dump capture.

Abstract: A method of additively manufacturing a composite article with tuned impedance and refractive-index in three dimensions. The method includes providing a ferrite feedstock. The ferrite feedstock is loaded with ferrite particles. The method further includes depositing and curing the ferrite feedstock. Therein a composite article is formed.

Abstract: A computer-implemented method for capturing system memory dumps includes receiving, by a diagnostic data component, an instruction to capture a system memory dump associated with a computer process being executed by a computing system comprising one or more processing units, the system memory dump comprising data from a plurality of memory locations associated with the computer process. In response to determining that the system memory dump satisfies a predetermined criterion, the diagnostic data component sends a request for a computing resource boost from the computing system. Further, in response to the request for the computing resource boost being granted, the diagnostic data component uses additional computing resources from the one or more processing units to store the data from the plurality of memory locations in the system memory dump and executing the backlogged operations that were halted due to the system memory dump capture.

Abstract: A method of additively manufacturing a composite article with tuned impedance and refractive-index in three dimensions. The method includes providing a ferrite feedstock. The ferrite feedstock is loaded with ferrite particles. The method further includes depositing and curing the ferrite feedstock. Therein a composite article is formed.

Abstract: A method of additively manufacturing a composite article with tuned impedance and refractive-index in three dimensions. The method includes providing a ferrite feedstock. The ferrite feedstock is loaded with ferrite particles. The method further includes depositing and curing the ferrite feedstock. Therein a composite article is formed.

Abstract: An additively manufactured article is assembled from a plurality of printed voxels. The article includes a lattice of unit cells of a composite lattice material and an encasing matrix of structural material arranged between adjacent unit cells of the lattice. The structural material has greater mechanical strength than the composite lattice material.

Abstract: A hat with a replaceable paracord chinstrap. A hat is provided that includes a removably attached paracord chinstrap. A chinstrap adjustment piece is attached to the hat and may be used to adjust the tightness around a wearer's chin. An instruction sheet is provided that includes instructions on how to attach the paracord chinstrap and adjustment piece and how to utilize the paracord chinstrap.

Abstract: The invention provides dosage regimes for treatment of synucleinopathies. In one regime, a subject receives 3000-5000 mg of an antibody intravenously every 3-5 weeks. In another regime, a subject receives 1300-1700 mg of an antibody intravenously every 3-5 weeks.

Abstract: A computer-implemented method, according to one approach, includes: receiving a first request to perform a write operation from a host, and performing the write operation. Metadata corresponding to the first request is sent to the secondary data storage device, and metadata corresponding to a second request to perform the write operation is received from the secondary data storage device, where the second request was received at the secondary data storage device from the host. The metadata corresponding to the first and second requests is used to determine whether the write operation has been mirrored across the primary and secondary data storage devices. In response to determining that the write operation has been mirrored across the primary and secondary data storage devices, a response is sent to the secondary data storage device which indicates that the write operation has been reconciled across the primary and secondary data storage devices.

Abstract: A computer-implemented method, according to one approach, includes: receiving a first request to perform a write operation from a host, and performing the write operation. Metadata corresponding to the first request is sent to the secondary data storage device, and metadata corresponding to a second request to perform the write operation is received from the secondary data storage device, where the second request was received at the secondary data storage device from the host. The metadata corresponding to the first and second requests is used to determine whether the write operation has been mirrored across the primary and secondary data storage devices. In response to determining that the write operation has been mirrored across the primary and secondary data storage devices, a response is sent to the secondary data storage device which indicates that the write operation has been reconciled across the primary and secondary data storage devices.

Abstract: A hat with a replaceable paracord chinstrap. A hat is provided that includes a removably attached paracord chinstrap. A chinstrap adjustment piece is attached to the hat and may be used to adjust the tightness around a wearer's chin. An instruction sheet is provided that includes instructions on how to attach the paracord chinstrap and adjustment piece and how to utilize the paracord chinstrap.

Abstract: A removable straw brim for a hard hat. The hard hat has a crown and brim. The removable straw brim is crownless and has center opening. An elastic center fabric band is sewn into the center opening and forms a center fabric band opening. A brim pocket is sewn to the bottom side of the straw hat brim. A plurality of elastic retention straps is also sewn to the bottom side of the straw hat brim. A hard hat is secured to the removable straw hat brim when the hard hat crown is inserted into the center fabric band opening and the center fabric band squeezes tightly around said crown, when the hard hat brim is inserted into the hard hat brim pocket, and when the elastic retention straps are wrapped around the hard hat.

Abstract: The present invention provides materials and methods for determining optimal dosage regimens for therapeutic agents. In particular, the invention relates to dosage regimens for therapeutic agents capable of targeting IL-2 receptor, preferably interleukin 2 (IL2)-based therapeutic agents. The methods of the invention allow general dosage regimens to be determined for new IL-2R targeted therapeutic agents but also specifically tailored dosage regimens to be achieved for individuals being treated with IL-2R targeted therapeutic agents.

Abstract: The invention provides dosage regimes for treatment of synucleinopathies. In one regime, a subject receives 3000-5000 mg of an antibody intravenously every 3-5 weeks. In another regime, a subject receives 1300-1700 mg of an antibody intravenously every 3-5 weeks.

Abstract: Provided are a method, system, and article of manufacture for configuring host settings to specify encryption and a key label referencing a key encrypting key to use to encrypt an encryption key provided to a storage drive to use to encrypt data from the host. User settings are received to configure a data class having data attributes with encryption settings. The data class is stored with the received user encryption settings. A job is received indicating a data set to store to a removable storage medium. A data class is determined having data class attributes matching data attributes of the data set indicated in the job. A determination is made from the determined data class whether to encrypt the data.

Abstract: Provided are a system and article of manufacture for providing an address format compatible with different addressing formats used for addressing different sized address spaces. An address format is used in an operating system to address storage space in a storage device comprising a first region and a second region of storage space. A first group of applications uses the address format to only address the storage space in the first region and is not coded to use the address format to access the second region and a second group of applications uses the address format to address the storage space in the first and second regions.

Abstract: Provided are a method, system, and article of manufacture for receiving an initial request from a first device to a second device. A response to the initial request is received from the second device to the first device. Each response and request received from the first device to the second device is processed by accessing the response or request from a packet encoded using a first communication protocol; generating a packet including the accessed response or request into a packet encoded using a second communication protocol; and transmitting the generated packet to the second device. Each response and request received from the second device to the first device is processed by accessing the response or request from a packet encoded using the second communication protocol; generating a packet including the accessed response or request into a packet encoded using the first communication protocol; and transmitting the generated packet to the second device.

Abstract: Provided are a system and article of manufacture for providing an address format compatible with different addressing formats used for addressing different sized address spaces. An address format is used in an operating system to address storage space in a storage device comprising a first region and a second region of storage space. A first group of applications uses the address format to only address the storage space in the first region and is not coded to use the address format to access the second region and a second group of applications uses the address format to address the storage space in the first and second regions.

Abstract: Provided are a method, system, and article of manufacture for configuring host settings to specify encryption and a key label referencing a key encrypting key to use to encrypt an encryption key provided to a storage drive to use to encrypt data from the host. User settings are received to configure a data class having data attributes with encryption settings. The data class is stored with the received user encryption settings. A job is received indicating a data set to store to a removable storage medium. A data class is determined having data class attributes matching data attributes of the data set indicated in the job. A determination is made from the determined data class whether to encrypt the data.