Patents by Inventor Peter Guzzo

Peter Guzzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050137215
    Abstract: This invention relates to a compound which is [c]-fused bicyclic proline derivative, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition comprising the compound or the salt thereof, and methods of treating diseases, including, but not limited to, methods of preventing or inhibiting joint cartilage damage and preventing or treating diseases characterized by joint cartilage damage, joint inflammation, or joint pain. The [c]-fused bicyclic proline derivatives are compounds of Formula I as described above. Diseases characterized by joint cartilage damage or joint pain include, for example, osteoarthritis and rheumatoid arthritis. Rheumatoid arthritis is also characterized by joint inflammation. This invention also relates to methods of synthesizing and preparing the [c]-fused bicyclic proline derivatives, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 12, 2004
    Publication date: June 23, 2005
    Inventors: Peter Guzzo, James Hamby, Matthew Johnson, Van-Duc Le, John Mangette, Rajesh Shenoy, Michael Stier
  • Patent number: 6841698
    Abstract: Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S,3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as processes for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: January 11, 2005
    Assignee: AstraZeneca AB
    Inventors: Thomas Elebring, Peter Guzzo, Marianne Swanson, Sverker Von Unge
  • Publication number: 20030220303
    Abstract: Novel compounds of formula I, with the exception of
    Type: Application
    Filed: April 4, 2003
    Publication date: November 27, 2003
    Inventors: Thomas Elebring, Peter Guzzo, Marianne Swanson, Sverker Von Unge
  • Patent number: 6596711
    Abstract: Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)methylphosphinic acid; ii) (S)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iii) (R)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iv) (3-amino-2-hydroxypropyl)difluoromethylphosphinic acid; and v) (3-amino-2-oxopropyl)methylphosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as a process for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: July 22, 2003
    Assignee: AstraZeneca AB
    Inventors: Kosrat Amin, Thomas Elebring, Peter Guzzo, Thomas Olsson, Marianne Swanson, Sverker Von Unge
  • Patent number: 6576626
    Abstract: Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S, 3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as processes for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: June 10, 2003
    Assignee: AstraZeneca AB
    Inventors: Thomas Elebring, Peter Guzzo, Marianne Swanson, Sverker Von Unge
  • Publication number: 20020156053
    Abstract: Novel compounds of formula I, with the exception of
    Type: Application
    Filed: March 1, 2001
    Publication date: October 24, 2002
    Inventors: Thomas Elebring, Peter Guzzo, Anders aq Holmen, Thomas Olsson, Marianne Swanson, Sverker Von Unge