Patents by Inventor Peter Gyory

Peter Gyory has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of pharmaceutical compositions
    Patent number: 4960913
    Abstract: The invention relates to a process for the preparation of tetracycline derivatives of the formula ##STR1## and acid addition salts thereof --wherein R stands for --CH.sub.3 or .dbd.CH.sub.2 --by dehalogenating and hydrogenating chloromethacycline or acid addition salt thereof of the formula ##STR2## or by hydrating methacycline or acid addition salts thereof of the formula ##STR3## by treatment with hydrogen gas in the presence of a noble metal alloy catalyst on carrier and organic solvent which comprises performing, hydrogenating under pressure of 0.1-1.0 MPa with an alloy catalyst consisting of the alloy palladium or platinum and selenium and/or tellurium used at a ratio of 1:0.01-0.5 related to the amount of the starting tetracycline and carrying out, if desired dehalogenation and hydrogenation in one step.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: October 2, 1990
    Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt.
    Inventors: Erzsebet Szalay, Gyorgy Lugosi, Tamas U. Kallay, Zsuzsanna Nad, Istvan Jelinek, Vilmos Simonidesz, Peter Gyory, Lajos Nagy, Marta Lugosi, Ilona Santa nee Singola, Gabor Besenyei, Laszlo Simandi
  • 7-oxo-PGI.sub.2 -ephedrine salts and their pharmaceutical compositions and methods
    Patent number: 4735965
    Abstract: The invention relates to new 7-oxo-PGI.sub.2 -ephedrine salt analogues of the Formula I ##STR1## wherein A stands for --(CH.sub.2).sub.2 --, cis or trans --CH.dbd.CH-- or --C.tbd.C--;R.sup.1 is lower alkyl or hydrogen;B represents a chemical bond, --CH.sub.2 -- or --CR.sup.2 R.sup.3 ;R.sup.2 stands for lower alkyl or hydrogen;R.sup.3 represents lower alkyl or hydrogen;X is a chemical bond, --O-- or --CH.sub.2 --;R.sup.4 stands for C.sub.1-6 alkyl, C.sub.4-7 cycloalkyl, C.sub.1-6 fluoroalkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, phenyl, substituted phenyl or heteroaryl.The salts of the Formula I show the same pharmacological profile as the sodium salt of PGI.sub.2, they inhibit blood aggregation and the secretion of gastric acid, are useful in the prevention of anginal attacks.
    Type: Grant
    Filed: May 28, 1986
    Date of Patent: April 5, 1988
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Gabor Kovacs, Geza Galambos, Istvan Tomoskozi, Karoly Kanai, Peter Gyory, Peter Kormoczy, Istvan Stadler, Laszlo Szekeres, Gyula Papp, Eva Udvary, Pal Hadhazy, Jeno Marton, Gyorgy Dorman
  • Selective biologically active 7-oxo-prostacyclin derivatives and pharmaceutical compositions containing same
    Patent number: 4588713
    Abstract: Compounds of the formula ##STR1## are disclosed wherein R.sup.1 stands for hydrogen, C.sub.1-4 straight or branched alkyl or pharmacologically acceptable cation,R.sup.2 stands for hydrogen, C.sub.1-4 alkanoyl, benzoyl, or benzoyl substituted by C.sub.1-4 alkyl or halogen, and R.sup.2 can further represent tetrahydropyranyl, trialkylsilyl or alkoxyalkyl,A stands for ethylene, cis or trans-vinylene or --C.dbd.C--,n may represent 2, 3 or 4. The compounds are highly effective in the inhibition of thrombocyte aggregation while at the same time exert only a very small hypotensive effect.
    Type: Grant
    Filed: January 14, 1985
    Date of Patent: May 13, 1986
    Assignee: Chinoin Gyogyszer Vegyeszeti Termekek Gyara Rt.
    Inventors: Peter Gyory, Geza Galambos, Karoly Kanay, Jozsef Ivanics, Gyorgy Dorman, Gabor Kovacs, Istvan Stadler, Sandor Virag, Istvan Tomoskozi, Peter Kormoczky, Marianna Kovacs
  • Vasodilative 4-thia-PGI.sub.1 and 4-sulfinyl-PGI.sub.1 and derivatives thereof
    Patent number: 4379164
    Abstract: A compound having vasodilative, bronchodilative, stomach-mucosa-protective and platelet-aggregation-inhibiting activity has the formulaA 4-thia- or 4-sulfinyl-PGI.sub.1 -compound of the formula I ##STR1## wherein Q stands for --S-- or --SO--,A stands for C.sub.1-6 straight or branched chain alkylene,B stands for ethylene, vinylene or ethinylene,R.sup.1 represents hydrogen or C.sub.1-4 alkyl,R.sup.2 represents C.sub.1-8 straight or branched chain alkyl or mono-substituted aryl-oxy-methyl,R.sup.3 stands for hydrogen or acetyl, andZ represents --COOH, --CN, --CH.sub.2 OH or --COOW, wherein W stands for an equivalent of a pharmacologically acceptable cation or C.sub.1-4 alkyl.
    Type: Grant
    Filed: October 23, 1981
    Date of Patent: April 5, 1983
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Tomoskozi, Peter Gyory, Gabor Kovacs, Sandor Virag, Peter Kormoczy, Istvan Stadler