Patents by Inventor Peter H. Dorff

Peter H. Dorff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLOALKYLAMINO ACID DERIVATIVES
    Publication number: 20100234435
    Abstract: The invention relates to compounds of formula I and to pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof. This invention also relates to a method of using such compounds in the treatment of hyperproliferative diseases and autoimmune diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: May 13, 2010
    Publication date: September 16, 2010
    Inventors: Samit K. Bhattacharya, Matthew F. Brown, Peter H. Dorff, Susan D. LaGreca, John W. Mickelson, Joseph A. Cornicelli, David L. Brown, Jennings Rex, John K. Walker, Rita Huff, Joseph W. Strohbach, Robert J. Maguire
  • CYCLOALKYLAMINO ACID DERIVATIVES
    Publication number: 20090227641
    Abstract: The invention relates to compounds of formula I and to pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof. This invention also relates to a method of using such compounds in the treatment of hyperproliferative diseases and autoimmune diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: November 7, 2008
    Publication date: September 10, 2009
    Inventors: Samit K. Bhattacharya, Matthew F. Brown, Peter H. Dorff, Susan D. LaGreca, John W. Mickelson, Joseph A. Cornicelli, David L. Brown, Rex Jennings, John K. Walker, Rita Huff, Joseph W. Strohbach, Robert J. Maguire
  • (N-(pyridinylmethyl)-heterocyclic)ylideneamine compounds as nicotinic acetylcholine receptor binding agents
    Patent number: 6020335
    Abstract: An (N-(pyridinylmethyl)-heterocyclic)ylideneamine compound of the formula ##STR1## wherein R.sup.3, A, and B are as described below, and its pharmaceutically acceptable salts and prodrugs. Compounds of the formula I and their pharmaceutically acceptable salts and prodrugs are useful in the treatment of addictive disorders, such as the use of tobacco or other nicotine containing products, neurological and mental disorders such as senile dementia of the Alzheimer's type, Parkinson's disease, attentional hyperactivity disorder, anxiety, obesity, Tourette's Syndrome and ulcerative colitis.
    Type: Grant
    Filed: November 4, 1997
    Date of Patent: February 1, 2000
    Assignee: Pfizer Inc
    Inventors: Arthur A. Nagel, Steven W. Goldstein, Stanley Jung, Peter H. Dorff
  • Biphenyl-2-carboxylic acid-tetrahydro-isoquinolin-6-yl amide derivatives, their preparation and their use as inhibitors of microsomal triglyceride transfer protein and/or apolipoprotein B (Apo B) secretion
    Patent number: 5919795
    Abstract: Compounds of formula (I), ##STR1## wherin X is CH.sub.2, CO, CS or SO.sub.2 ; Y is selected from: a direct link, aliphatic hydrocarbylene radicals having up to 20 carbon atoms, which radical may be mono-substituted by hydroxy, (C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.10)acyl, (C.sub.1 -C.sub.10)acyloxy, or (C.sub.6 -C.sub.10)aryl, NH, and O, provided that if X is CH.sub.2,Y is a direct link; Z is selected from the following groups: (1) H, halo, cyano, (2) hydroxy, (C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.10)a1kylthio, (C.sub.1 -C.sub.10)acyl, thiophenylcaronyl (C.sub.1 -C.sub.10)alkoxycarbonyl, (3) (C.sub.1 -C.sub.10)aklkyammo, di(C.sub.1 -C.sub.10)alylamino, (C.sub.6 -C.sub.10)aryl(C.sub.1 -C.sub.10)alkylamino, provided that Y is not O or NH, (4) unsubstituted vinyl, (C.sub.6 -C.sub.10)aryl, (C.sub.3 -C.sub.8)cycloalkyl and fused benz derivatives thereof, (C.sub.7 -C.sub.10)polycycloalkyl, (C.sub.4 -C.sub.8)cycloalkenyl, (C.sub.7 -C.sub.10)polycycloalkenyl, (5) (C.sub.6 -C.sub.10)aryloxy, (C.sub.6 -C.
    Type: Grant
    Filed: November 28, 1997
    Date of Patent: July 6, 1999
    Assignee: Pfizer INc.
    Inventors: George Chang, Peter H. Dorff, George J. Quallich