Patents by Inventor Peter H. Smith
Peter H. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240122479Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: ApplicationFiled: December 21, 2023Publication date: April 18, 2024Inventors: Peter H. SMITH, Manish KANKARIA, Priyanshu GUPTA, Nicholas J. SPINELLI, Charles W. MCNALL
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Publication number: 20240094233Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.Type: ApplicationFiled: July 18, 2023Publication date: March 21, 2024Inventors: Jacob N. WOHLSTADTER, Manish KOCHAR, Peter J. BOSCO, Ian D. CHAMBERLIN, Bandele JEFFREY-COKER, Eric M. JONES, Gary I. KRIVOY, Don E. KRUEGER, Aaron H. LEIMKUEHLER, Pei-Ming WU, Kim-Xuan NGUYEN, Pankaj OBEROI, Louis W. PANG, Jennifer PARKER, Victor PELLICIER, Nicholas SAMMONS, George SIGAL, Michael L. VOCK, Stanley T. SMITH, Carl C. STEVENS, Rodger D. OSBORNE, Kenneth E. PAGE, Michael T. WADE, Jon WILLOUGHBY, Lei WANG, Xinri CONG, Kin NG
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Patent number: 11890076Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: GrantFiled: July 28, 2020Date of Patent: February 6, 2024Assignee: Avinger, Inc.Inventors: Peter H. Smith, Manish Kankaria, Priyanshu Gupta, Nicholas J. Spinelli, Charles W. McNall
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Patent number: 11723538Abstract: Optical pressure sensor assemblies that can be used with existing catheters and imaging systems. Pressure sensors may be compatible with atherectomy and occlusion-crossing catheters, where intravascular pressure measurements at various vessel locations are needed to determine treatment efficacy. The pressure sensors may employ an optical pressure measurement mechanism using optical interferometry, and may be integrated with existing imaging modalities such as OCT. The pressure sensor assemblies may include a movable membrane that deflects in response to intravascular pressure; an optical fiber that transmits light to the movable membrane and receives light reflected or scattered back from the movable membrane into the fiber; and a processor or controller configured to determine the distance traveled by the light received in the fiber from the movable membrane, where the distance traveled is proportional to the intravascular pressure exerted against the membrane.Type: GrantFiled: March 1, 2021Date of Patent: August 15, 2023Assignee: AVINGER, INC.Inventors: Peter H. Smith, Manish Kankaria
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Publication number: 20220039658Abstract: Optical pressure sensor assemblies that can be used with existing catheters and imaging systems. Pressure sensors may be compatible with atherectomy and occlusion-crossing catheters, where intravascular pressure measurements at various vessel locations are needed to determine treatment efficacy. The pressure sensors may employ an optical pressure measurement mechanism using optical interferometry, and may be integrated with existing imaging modalities such as OCT. The pressure sensor assemblies may include a movable membrane that deflects in response to intravascular pressure; an optical fiber that transmits light to the movable membrane and receives light reflected or scattered back from the movable membrane into the fiber; and a processor or controller configured to determine the distance traveled by the light received in the fiber from the movable membrane, where the distance traveled is proportional to the intravascular pressure exerted against the membrane.Type: ApplicationFiled: March 1, 2021Publication date: February 10, 2022Applicant: Avinger, Inc.Inventors: Peter H. SMITH, Manish KANKARIA
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Publication number: 20210330345Abstract: A catheter device for crossing occlusions includes an elongate catheter shaft, a rotatable tip configured to rotate relative to the elongate catheter shaft, a drive shaft, and an OCT imaging sensor. The rotatable tip includes a housing coupled with the elongate catheter shaft and cutting wedges extendable from the housing. The drive shaft has a central lumen extending therethrough and extends within the elongate catheter shaft. The drive shaft is coupled with the wedges and is configured to rotate the rotatable tip. The OCT sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. The elongate catheter shaft is configured to move axially over the drive shaft to extend and retract the wedges from the housing while maintaining a fixed position of the imaging sensor relative to the cutting wedges.Type: ApplicationFiled: March 22, 2021Publication date: October 28, 2021Inventors: Richard R. NEWHAUSER, Theodore W. KETAI, Peter H. SMITH, Myra L. FABRO
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Publication number: 20210107078Abstract: A dielectric gel for use in electro-discharge machining. Aspects of the dielectric gel include a liquid solvent phase entrapped in a three-dimensionally cross-linked fibre network.Type: ApplicationFiled: September 29, 2020Publication date: April 15, 2021Applicant: ROLLS-ROYCE plcInventors: Shamraze AHMED, Adam CLARE, James KELL, Daniel CLARK, Alistair G. SPEIDEL, Monica M. CASTRO PALACIOS, Peter H. SMITH, Donka NOVOVIC
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Patent number: 10952763Abstract: A catheter device for crossing occlusions includes an elongate catheter shaft, a rotatable tip configured to rotate relative to the elongate catheter shaft, a drive shaft, and an OCT imaging sensor. The rotatable tip includes a housing coupled with the elongate catheter shaft and cutting wedges extendable from the housing. The drive shaft has a central lumen extending therethrough and extends within the elongate catheter shaft. The drive shaft is coupled with the wedges and is configured to rotate the rotatable tip. The OCT sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. The elongate catheter shaft is configured to move axially over the drive shaft to extend and retract the wedges from the housing while maintaining a fixed position of the imaging sensor relative to the cutting wedges.Type: GrantFiled: April 16, 2018Date of Patent: March 23, 2021Assignee: Avinger, Inc.Inventors: Richard R. Newhauser, Theodore W. Ketai, Peter H. Smith, Myra L. Fabro
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Publication number: 20210076949Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: ApplicationFiled: July 28, 2020Publication date: March 18, 2021Inventors: Peter H. SMITH, Manish KANKARIA, Priyanshu GUPTA, Nicholas J. SPINELLI, Charles W. MCNALL
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Patent number: 10932670Abstract: Optical pressure sensor assemblies that can be used with existing catheters and imaging systems. Pressure sensors may be compatible with atherectomy and occlusion-crossing catheters, where intravascular pressure measurements at various vessel locations are needed to determine treatment efficacy. The pressure sensors may employ an optical pressure measurement mechanism using optical interferometry, and may be integrated with existing imaging modalities such as OCT. The pressure sensor assemblies may include a movable membrane that deflects in response to intravascular pressure; an optical fiber that transmits light to the movable membrane and receives light reflected or scattered back from the movable membrane into the fiber; and a processor or controller configured to determine the distance traveled by the light received in the fiber from the movable membrane, where the distance traveled is proportional to the intravascular pressure exerted against the membrane.Type: GrantFiled: March 15, 2013Date of Patent: March 2, 2021Assignee: Avinger, Inc.Inventors: Peter H. Smith, Manish Kankaria
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Patent number: 10722121Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: GrantFiled: December 26, 2017Date of Patent: July 28, 2020Assignee: Avinger, Inc.Inventors: Peter H. Smith, Manish Kankaria, Priyanshu Gupta, Nicholas J. Spinelli, Charles W. McNall
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Patent number: 10548478Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.Type: GrantFiled: March 15, 2013Date of Patent: February 4, 2020Assignee: Avinger, Inc.Inventors: John B. Simpson, Priyanshu Gupta, Michael Zung, Wendy N. Lam, Maegan K. Spencer, Peter H. Smith, Stephen C. Davies, Nicholas J. Spinelli, Charles W. McNall, Theodore W. Ketai, Manish Kankaria, Mark W. Askew, Kent C. B. Stalker
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Publication number: 20190021760Abstract: A catheter device for crossing occlusions includes an elongate catheter shaft, a rotatable tip configured to rotate relative to the elongate catheter shaft, a drive shaft, and an OCT imaging sensor. The rotatable tip includes a housing coupled with the elongate catheter shaft and cutting wedges extendable from the housing. The drive shaft has a central lumen extending therethrough and extends within the elongate catheter shaft. The drive shaft is coupled with the wedges and is configured to rotate the rotatable tip. The OCT sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. The elongate catheter shaft is configured to move axially over the drive shaft to extend and retract the wedges from the housing while maintaining a fixed position of the imaging sensor relative to the cutting wedges.Type: ApplicationFiled: April 16, 2018Publication date: January 24, 2019Inventors: Theodore W. Ketai, Peter H. Smith, Myra L. Fabro
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Publication number: 20180368688Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.Type: ApplicationFiled: March 15, 2013Publication date: December 27, 2018Inventors: John B. Simpson, Priyanshu Gupta, Michael Zung, Wendy N. Lam, Maegan K. Spencer, Peter H. Smith, Stephen C. Davies, Nicholas J. Spinelli, Charles W. McNall, Theodore W. Ketai, Manish Kankaria, Mark W. Askew, Kent C. B. Stalker
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Publication number: 20180256039Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: ApplicationFiled: December 26, 2017Publication date: September 13, 2018Inventors: Peter H. SMITH, Manish KANKARIA, Priyanshu GUPTA, Nicholas J. SPINELLI, Charles W. MCNALL
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Patent number: 9854979Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: GrantFiled: March 15, 2013Date of Patent: January 2, 2018Assignee: Avinger, Inc.Inventors: Peter H. Smith, Manish Kankaria, Priyanshu Gupta, Nicholas J. Spinelli, Charles W. McNall
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Patent number: 9737251Abstract: A system for needle-free drawing of blood is disclosed. A device can include an evacuated negative-pressure barrel with a membrane sealing an aperture at a distal end, and a housing affixed to a proximal end. An accelerator barrel can be positioned within the negative-pressure barrel and fixed to the housing, with an open proximal end in a chamber in the housing, and an open distal end aligned with the aperture. The chamber can be filled with pressurized gas, and a trigger valve can hydrostatically separate the chamber from the open proximal end of the accelerator barrel. A micro-particle positioned within the accelerator barrel can be accelerated to high speed by an abrupt surge of gas by releasing the trigger valve. The micro-particle can attain enough momentum to pierce the aperture membrane and penetrate adjacent dermal tissue. A resulting micro-emergence of blood can be drawn into the negative pressure barrel.Type: GrantFiled: May 28, 2014Date of Patent: August 22, 2017Assignee: Verily Life Sciences LLCInventors: Eric Peeters, Peter H. Smith
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Publication number: 20160144155Abstract: An occlusion sheath having an expandable member is described herein. The occlusion sheath is configured to occlude or limit blood flow to a vessel while providing a central lumen to allow a catheter, such as an imaging catheter and/or an atherectomy catheter, to travel therethrough.Type: ApplicationFiled: July 1, 2014Publication date: May 26, 2016Inventors: John B. SIMPSON, Theodore W. KETAI, Mark W. ASKEW, Serena S. LOH, Guip T. NGUYEN, Stephen C. DAVIES, Richard R. NEWHAUSER, Peter H. SMITH
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Publication number: 20160038030Abstract: Optical pressure sensor assemblies that can be used with existing catheters and imaging systems. Pressure sensors may be compatible with atherectomy and occlusion-crossing catheters, where intravascular pressure measurements at various vessel locations are needed to determine treatment efficacy. The pressure sensors may employ an optical pressure measurement mechanism using optical interferometry, and may be integrated with existing imaging modalities such as OCT. The pressure sensor assemblies may include a movable membrane that deflects in response to intravascular pressure; an optical fiber that transmits light to the movable membrane and receives light reflected or scattered back from the movable membrane into the fiber; and a processor or controller configured to determine the distance traveled by the light received in the fiber from the movable membrane, where the distance traveled is proportional to the intravascular pressure exerted against the membrane.Type: ApplicationFiled: March 15, 2013Publication date: February 11, 2016Inventors: Peter H. SMITH, Manish KANKARIA
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Publication number: 20160029902Abstract: An imaging device includes a hollow flexible shaft having a central longitudinal axis and an imaging window therein. An optical fiber extends within the hollow flexible shaft substantially along the central axis. A distal tip of the optical fiber is attached to the hollow flexible shaft and aligned with the imaging window so as to transfer an optical coherence tomography signal through the imaging window. A handle is attached to the hollow flexible shaft configured rotate the hollow flexible shaft at speeds of greater than 1,000 rpm.Type: ApplicationFiled: March 15, 2013Publication date: February 4, 2016Inventors: Peter H. SMITH, Manish KANKARIA, Priyanshu GUPTA, Nicholas J. SPINELLI, Charles W. MCNALL