Abstract: A chimeric antigen receptor (CAR) that binds CD117 (anti-CD117 CAR), wherein the anti-CD117 CAR comprises: (a) an ectodomain that binds CD 117; (b) a transmembrane domain; and (c) an endodomain comprising a costimulatory domain and a CD3? signaling domain. The ectodomain comprises a single chain variable fragment (scFv) that binds CD 117 (anti-CD117 scFv), or comprises a single domain antibody fragment such as a VHH fragment. Also provided herein are genetically engineered T cells expressing such anti-CD117 CAR, which can be used for inhibiting CD117+ cells such as cancer cells.

Abstract: Sheet metal fasteners and/or washers of the type which are used to fasten membranes to cementitious materials of a type such as utilized in roofing wherein the fasteners are treated to provide a corrosion resistant coating to the washers and those portions of the fasteners not inserted into the cementitious material.

Abstract: A tool for driving metallic fasteners which includes a magnetic driving head defined by partially separated segments of opposite polarity which are spaced from one another along a portion of their width, but which are integrally connected by an integrally formed reinforcing bridge element so that the impacting surface of the tool is generally continuous except for spaced grooves which extend inwardly of the impacting surface of the tool and which partially separate the magnetized segments from one another.