Patents by Inventor Peter Harrington
Peter Harrington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240123112Abstract: The invention relates in a first main aspect to self-supporting mistletoe viscin films comprising a 2-dimensional multi-axial oriented array of viscin cellulose filaments within a humidity-responsive matrix and methods for preparing the same. A further aspect relates to 2D and 3D mistletoe viscin scaffolds and methods for preparing the same. Another main aspect of the invention relates to the use of mechanically isolated mistletoe viscin or of said self-supporting mistletoe viscin films for joining or binding together a plurality of materials with diverse surface characteristics and to an adhesive comprising such viscin films and/or 2D or 3D viscin scaffolds. In more specific embodiments, the invention relates to a wound sealant and coating composition or to a medical kit comprising mechanically isolated mistletoe viscin in the hydrated/wet state and a plant oil, or a dried viscin film for use, after rehydration under humid conditions, as a wound sealant.Type: ApplicationFiled: February 23, 2022Publication date: April 18, 2024Inventors: Matthew HARRINGTON, Peter FRATZL, Nils HORBELT
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Patent number: 11951110Abstract: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula: wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.Type: GrantFiled: February 2, 2022Date of Patent: April 9, 2024Assignee: WisTa Laboratories Ltd.Inventors: Claude Michel Wischik, Janet Elizabeth Rickard, Charles Robert Harrington, David Horsley, John Mervyn David Storey, Colin Marshall, James Peter Sinclair, Thomas Craven Baddeley
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Publication number: 20170292266Abstract: A system for the modular construction of partitions, the system comprising a plurality of modules, each module comprising a security panel and a frame, the security panel being attached to one or more surface of the frame, the frame comprising at least one box shaped profile, each profile being adapted for connection to an adjacent profile of an adjacent module or to a structural building member.Type: ApplicationFiled: June 26, 2017Publication date: October 12, 2017Applicant: PRINCIPLE HOLDINGS LIMITEDInventors: Peter HARRINGTON, Alasdair Colin MCGREGOR
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Publication number: 20150020470Abstract: A system for the modular construction of partitions, the system comprising a plurality of modules, each module comprising a security panel and a frame, the security panel being attached to one or more surface of the frame, the frame comprising at least one box shaped profile, each profile being adapted for connection to an adjacent profile of an adjacent module or to a structural building member.Type: ApplicationFiled: October 3, 2014Publication date: January 22, 2015Inventors: Peter HARRINGTON, Alasdair Colin McGREGOR
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Publication number: 20120073233Abstract: A system for the modular construction of partitions, the system comprising a plurality of modules, each module comprising a security panel and a frame, the security panel being attached to one or more surface of the frame, the frame comprising at least one box shaped profile, each profile being adapted for connection to an adjacent profile of an adjacent module or to a structural building member.Type: ApplicationFiled: September 16, 2011Publication date: March 29, 2012Applicant: PRINCIPLE HOLDINGS LIMITEDInventors: Peter HARRINGTON, Alasdair Colin McGREGOR
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Patent number: 7646108Abstract: Some embodiments include a die having an output control circuit to interact with an output circuit to convert a source voltage into at least one output voltage. The die may also have a converter circuit to convert the output voltage into at least one additional output voltage.Type: GrantFiled: September 29, 2006Date of Patent: January 12, 2010Assignee: Intel CorporationInventors: Fabrice Paillet, Nick Triantafillou, Azam Barkatullah, Daniel Elmhurst, Peter Harrington, Raymond W. Zeng
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Publication number: 20080080103Abstract: Some embodiments include a die having an output control circuit to interact with an output circuit to convert a source voltage into at least one output voltage. The die may also have a converter circuit to convert the output voltage into at least one additional output voltage.Type: ApplicationFiled: September 29, 2006Publication date: April 3, 2008Inventors: Fabrice Paillet, Nick Triantafillou, Azam Barkatullah, Daniel Elmhurst, Peter Harrington, Raymond W. Zeng
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Publication number: 20070197797Abstract: Compounds having bi-cyclic structure comprising a partially unsaturated 6-carbon first cyclic moiety interconnected to a 6-carbon second cyclic moiety second via a divalent linking moiety are provided. The compounds can be used as intermediates compounds in methods for the synthesis of carbazoles and derviatives thereof, including carvedilol, and tricyclic alkylhydroxamates, which do not require Fischer indole synthetic steps. Methods of preparing the compounds having bi-cyclic structures are also provided.Type: ApplicationFiled: December 28, 2006Publication date: August 23, 2007Inventor: Peter Harrington
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Publication number: 20070129554Abstract: Methodologies for the alpha-monohalogenation of acid sensitive ketones, especially cyclic, acid-sensitive, ketalized ketones. As one approach, the ketone is reacted with a halogen donor compound, e.g., N-chlorosuccinimide, in anhydrous, highly polar organic reagents such as dimethylformamide (DMF). As another monohalogenation approach, it has been observed that organic salts generated from amines and carboxylic acids catalyze the monohalogenation of ketalized ketone in reagents comprising alcohol solvent (methanol, ethanol, isopropanol, etc.). The monohalogenation is fast even at ?5° C. The salt can be rapidly formed in situ from ingredients including amines and/or carboxylic acids without undue degradation of the acid sensitive ketal. Aryl ketones are monooxygenated using iodosylbenzene. This methodology is applied to monohalogenation of an acid sensitive monoketal ketone. The ability to prepare monohalogenated, acid sensitive ketones facilitates syntheses using halogenated, acid sensitive ketones.Type: ApplicationFiled: October 19, 2006Publication date: June 7, 2007Inventors: Peter Harrington, Hiralal Khatri, Sudha Khatri
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Publication number: 20070103994Abstract: Embodiments of an inductive charge pump are generally described herein. Other embodiments may be described and claimed.Type: ApplicationFiled: November 4, 2005Publication date: May 10, 2007Inventors: Muneer Ahmed, Johnny Javanifard, Peter Harrington
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Publication number: 20060014959Abstract: The present invention provides a process for preparing a pyridine compound of the formula: wherein R1, R2, R3 and a are those defined herein.Type: ApplicationFiled: July 5, 2005Publication date: January 19, 2006Applicants: Roche Colorado CorporationInventors: Peter Harrington, David Johnston, L. Hodges
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Publication number: 20050157260Abstract: A stereoscopic imaging lens includes a first lens set and a second lens set. The lens receives collimated laser light from the scanning laser ophthalmoscope and, focuses on the fundus of the eye. By use of a prism set, two offset images are provided to the scanning laser ophthalmoscope. The system provides virtually simulatneous side-by-side but offset images that can be viewed with a stereoscopic viewing device, which provides apparent depth perception.Type: ApplicationFiled: November 12, 2004Publication date: July 21, 2005Inventors: Raymond Graham, Peter Harrington, Giovanni Staurenghi
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Publication number: 20050014792Abstract: The present invention relates to a process for the manufacture of compounds of formula wherein the substituents are as described herein which comprises the steps of a) reacting a compound of formula with a compound of formula to form a compound of formula b) converting the OH/?O function of compounds of formula XIV/XIVa into a leaving group P with a reagent containing a leaving group, selected from POCl3, PBr3, MeI and (F3CSO2)2O to form a compound of formula wherein P is halogen or trifluoromethanesulfonate; c) substituting R2 for the leaving group P by reacting compound XV with HR2 to form a compound of formula and d) hydrolyzing the nitrile function in an acidic medium selected from H2SO4, HCl and acetic acid, to form a compound of formula I The compounds of formula I are valuable intermediates for the manufacture of therapeutically active compounds which have NK-1 antagonist activity.Type: ApplicationFiled: July 9, 2004Publication date: January 20, 2005Inventors: Wolfgang Goehring, Peter Harrington, Lewis Hodges, David Johnston, Goesta Rimmler
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Publication number: 20040220230Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: 1Type: ApplicationFiled: January 29, 2004Publication date: November 4, 2004Applicant: SmithKline Beecham p.l.c.Inventors: Laramie Mary Gaster, Michael Stewart Hadley, John David Harling, Frank Peter Harrington, Jag Paul Heer, Thomas Daniel Heightman, Andrew Hele Payne
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Patent number: 6762192Abstract: Compounds of formula (I) and pharmaceutically acceptable salts and solvates: where R1 is hydrogen, C1-6 alkyl (optionally substituted by hydroxy or C1-4alkoxy), phenyl-C1-4alkyl-, C1-6alkenyl, C1-6alkynyl; R2 is hydrogen or up to three substituents selected from halogen, NO2, CN, N3, CF3O—, CF3S—, CF3CO—, C1-6alkyl, C1-6alkenyl, C1-6alkynyl, C1-6perfluoroalkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-4alkyl-, C1-6alkylO—, C1-6alkylCO—, C3-6cycloalkylO—, C3-6cycloalkylCO—, C3-6cycloalkyl-C1-4alkylO—, C3-6cycloalkyl-C1-4alkylCO—, phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C1-4alkyl-, C1-6alkylS—, C1-6alkylSO2—, (C1-4alkyl)2NSO2—, (C1-4alkyl)NHSO2—, (C1-4alkyl)2NCO—, (C1-4alkyl)NHCO— or CONH2; or —NR5R6 where R5 is hydrogen or C1-4 alkyl, and R6 is hydrogen, C1-4alkyl, formyl, —CO2C1-4alkyl or —COC1-4alkyl; or two R2 groups together form a carbocyclic ring that is saturated or unsaturated.Type: GrantFiled: May 23, 2002Date of Patent: July 13, 2004Assignee: SmithKline Beechum p.l.c.Inventors: John David Harling, Frank Peter Harrington, Mervyn Thompson
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Publication number: 20030166633Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R1, R2 and R3 represent various functional groups, and one of X1 and X2 is N and the other is NR10; and their use as pharmaceuticals.Type: ApplicationFiled: October 29, 2002Publication date: September 4, 2003Inventors: Laramie Mary Gaster, Michael Stewart Hadley, John David Harling, Frank Peter Harrington, Jag Paul Heer, Thomas Daniel Heightman, Andrew Hele Payne
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Patent number: 6600035Abstract: Compounds of formula (I) in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula (a) wherein R4 and R5 are independently hydrogen or one or more substituents replacing hydrogen atoms in the ring system shown; m is 2 or 3; p is 0, 1 or 2; and R3 is hydrogen, a salt-forming cation or an ester-forming group; and the symbol ═/═ indicates that the double bond may be in either the E or Z configuration.Type: GrantFiled: May 24, 1995Date of Patent: July 29, 2003Assignee: SMithKline Beecham p.l.c.Inventors: Nigel John Perryman Broom, Frank Peter Harrington
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Publication number: 20020143029Abstract: Compounds of formula (I) and pharmaceutically acceptable salts and solvates: 1Type: ApplicationFiled: May 23, 2002Publication date: October 3, 2002Applicant: SmithKline Beecham p.l.c.Inventors: John David Harling, Frank Peter Harrington, Mervyn Thompson
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Patent number: 6410555Abstract: Compounds of formula (I) and pharmaceutically acceptable salts and solvates: where R1 is hydrogen, C1-6alkyl (optionally substituted by hydroxy or C1-4alkoxy), phenyl-C1-4alkyl-, C1-6alkenyl, C1-6alkynyl; R2 is hydrogen or, up to three substituents selected from halogen, NO2, CN, N3, CF3O—, CF3S—, CF3SO2—, CF3CO—, C1-6alkyl, C1-6alkenyl, C1-6alkynyl, C1-6perfluoroalkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-4alkyl-, C1-6alkyl, C1-6alkylCO—, C3-6cycloalkylO—, C3-6cycloalkylCO—, C3-6cycloalkyl-C1-4alkylO—, C3-6cycloalkyl-C1-4alkylCO—, phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C1-4alkyl-, C1-6alkylS—, C1-6alkylSO2—, (C1-4alkyl)2NSO2—, (C1-4alkyl)NHSO2—, (C1-4alkyl)2NCO—, (C1-4alkyl)NHCO— or CONH2; or —NR5R6 where R5 is hydrogen or C1-4alkyl, and R6 is hydrogen, C1-4alkyl, formyl, —CO2C1-4alkyl or —COC1-4alkyl; or two R2 groups together form a carbocyclic ring that is saturated or unsaturated, optionally inteType: GrantFiled: February 16, 2001Date of Patent: June 25, 2002Assignee: SmithKline Beecham p.l.c.Inventors: John David Harling, Frank Peter Harrington, Mervyn Thompson
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Patent number: 6245778Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: where R1 is hydrogen, C1-6 alkyl optionally substituted by hydroxy or C1-4alkoxy, or C1-6 alkylphenyl; R2 is hydrogen or up to three substituents selected from halogen, NO2, CN, N3, C1-6 alkylO-, C1-6 alkylS-, C1-6 alkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-4alkyl-, C1-6alkenyl, C1-6alkynyl, CF3, CF3O, CF3CO—, C1-6alkylCO-, C3-6cycloalkylCO-, C3-6cycloalkyl-C1-4alkylCO-, phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C1-4alkyl-, or —NR3R4 where R3 is hydrogen or C1-4 alkyl, and R4 is hydrogen, C1-4alkyl, —CHO, —CO2C1-4alkyl or —COC1-4alkyl; or two R2 groups form a saturated carbocyclic ring optionally interrupted by oxygen; and X is selected from hydrogen, halogen, cyano, alkyl and alkoxy; are useful in the treatment and prophylaxis of inter alia epilepsy.Type: GrantFiled: November 23, 1999Date of Patent: June 12, 2001Assignee: SmithKline Beecham p.l.c.Inventors: Michael Stewart Hadley, John David Harling, Frank Peter Harrington, Mervyn Thompson, Robert William Ward