Abstract: A computer system includes a token repository configured to store payment tokens, and a server system. The server system includes a processor and instructions stored in non-transitory machine-readable media, the instructions configured to cause the server system to receive a request to provision a payment token based on a financial product, wherein the request includes information related to the financial product, provision a payment token based on the token request, including authenticating the financial product based on the financial product information and generating the payment token upon authenticating the financial product, wherein the payment token is useable to make a payment via the financial product, and store the payment token in the token repository.

Abstract: A computer system includes a token repository configured to store payment tokens, and a server system. The server system includes a processor and instructions stored in non-transitory machine-readable media, the instructions configured to cause the server system to receive a request to provision a payment token based on a financial product, wherein the request includes information related to the financial product, provision a payment token based on the token request, including authenticating the financial product based on the financial product information and generating the payment token upon authenticating the financial product, wherein the payment token is useable to make a payment via the financial product, and store the payment token in the token repository.

Abstract: The invention relates to a method and a device (10) for determining the relevance of preparations (4) of sample arrays (1), containing a plurality of individual samples (3) at various positions. To produce a method or a device (10) that can be performed as quickly as possible and preferably without destroying the preparations (4), a device (11) is provided for non-destructive scanning of the preparations (4) of the sample arrays (1), which is connected to a database (12) that contains information on the positions of the individual samples (3) of the preparations (4) and to a computer unit (16) for processing the scanned preparations (4) and for generating data fields for each individual sample (3) and for selecting at least one parameter from each individual sample data field and for comparing this parameter or a value derived therefrom or a combination of parameters or values derived therefrom to at least one threshold value.

Abstract: The invention relates to a method for automatic analysis of biological samples, in particular tissue samples, comprising a device (11) for scanning the samples (1) for forming data sets (4) of the samples (1). To produce a method or a device (10) by which the regions of interest (ROI) of the sample (1) can be determined as quickly as possible and as much as possible without destroying the samples (1), at least one parameter (P) is selected without destroying the sample (1) from a data set (4) of the sample (1) that is formed by using autofluorescence, and this parameter or a value derived therefrom or a combination of parameters (P) or values derived therefrom is compared to at least one threshold value (S), and the comparison value is used as a criterion for determining regions of interest (ROI) of the sample (1) and stored together with a unique identification (ID) of the sample (1).

Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.

Abstract: The invention relates to the therapeutic or prophylactic treatment of fungal infections. The invention provides new methods for therapeutically or prophylactically treating fungal infections using sub-lethal concentrations of an anti-invasin compound. The methods according to the invention have fewer toxicology problems than existing methods, and thus can be used prophylactically, as well as for early treatment for high risk patients without a firm diagnosis. The methods according to the invention can also be used to treat an established fungal infection. The invention further provides novel genes that regulate fungal hyphal growth.

Abstract: The present invention relates to the method of treatment or prophylaxis of patients with drug-induced liver diseases which comprises administering to the patient in need thereof a therapeutically effective amount of a mitochondrially targeted antioxidant compound e.g. derivatives of vitamin E, coenzyme Q10 or a glutathione peroxidase mimetic. The present invention also relates to pharmaceutical compositions containing the antioxidant(s) intended for such use.

Abstract: Methods for improving secondary metabolite production by modulating certain genes involved in secondary metabolite production, including genes encoding CreA, AreA, GanB, Gna3, FadA, Gna1, Gpa1, RfeH, An09, PacC, Lys14, LovU, Ste7, Pde2, Nc1, Vps34 and fungal homologs thereof.

Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.

Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.

Abstract: The invention relates to the therapeutic or prophylactic treatment of fungal infections. The invention provides new methods for therapeutically or prophylactically treating fungal infections using sub-lethal concentrations of an anti-invasin compound. The methods according to the invention have fewer toxicology problems than existing methods, and thus can be used prophylactically, as well as for early treatment for high risk patients without a firm diagnosis. The methods according to the invention can also be used to treat an established fungal infection. The invention further provides novel genes that regulate fungal hyphal growth.

Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.

Abstract: The invention relates to the modulation of fungal signaling pathways. More particularly, the invention relates to compounds that modulate such pathways and to methods for identifying such compounds. The invention provides novel modulators of fungal gene expression that can be used to regulate or modulate activities of specific signaling pathways and to identify and validate potential targets in drug discovery efforts.

Abstract: Disclosed herein is a chimeric protein comprising a pre-activated transcription factor and a strong transcription activation domain for regulating fungal gene expression, and reagents and methods for constructing and using said protein.

Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.

Abstract: The invention relates to the production of secondary metabolites by fungi. More particularly, the invention relates to improvement of production of commercially important secondary metabolites by fungi. The invention provides methods for improving secondary metabolite production in a fungus, comprising modulating the expression of a gene involved in regulation of secondary metabolite production.

Abstract: Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.