Abstract: An elapsed time indicator comprises a reservoir of a fluid, a porous sheet element and a fluid port located between the reservoir and the porous sheet element. The porous sheet element defines a predetermined area which is separated from the fluid port by a predetermined lateral distance. The fluid is selectively provided from the reservoir to the porous sheet element through the fluid port whereupon the porous sheet element transmits the fluid laterally through the porous sheet element at a predetermined rate away from the fluid port until the fluid impregnates the predetermined area of the porous sheet element so as to cause the predetermined area of the porous sheet element to become transparent or more transparent after expiry of a predetermined time period.

Abstract: An elapsed time indicator comprises a porous element, an electrical source, and an electronic controller. The electronic controller is configured to receive electrical power from the electrical source and cause a fluid to be received by the porous element in response to expiry of a predetermined time period. The predetermined time period may be associated with an item such as a perishable item with which the elapsed time indicator is to be associated or to which the elapsed time indicator is to be attached. The predetermined time period may comprise a lifetime or a shelf-life of the item or a predetermined proportion of a lifetime or a shelf-life of the item.

Abstract: To predict which Hepatitis C patients are at high-risk for disease progression or adverse health outcomes, baseline characteristics are measured for patients as well as longitudinal data, including clinical, laboratory and/or biopsy results, which may be collected periodically in follow-up visits with a healthcare professional. A machine learning engine may predict whether a patient is at high-risk for disease progression or adverse health outcomes based on the baseline characteristics and the longitudinal data for the patient.

Abstract: An elapsed time indicator comprises a reservoir of a fluid, a porous sheet element and a fluid port located between the reservoir and the porous sheet element. The porous sheet element defines a predetermined area which is separated from the fluid port by a predetermined lateral distance. The fluid is selectively provided from the reservoir to the porous sheet element through the fluid port whereupon the porous sheet element transmits the fluid laterally through the porous sheet element at a predetermined rate away from the fluid port until the fluid impregnates the predetermined area of the porous sheet element so as to cause the predetermined area of the porous sheet element to become transparent or more transparent after expiry of a predetermined time period.

Abstract: The present invention is directed in various methods, devices and systems relating to rotational atherectomy. More specifically, an oscillating driver is connected to a drive shaft, or torque transfer tube, with abrasive element mounted thereon. The result provides a rotational working diameter for the rotating abrasive element that is larger than its resting diameter. Generally, the preferred abrasive element is concentric in profile and/or with center of mass collinear with the drive shaft's rotational axis. However, eccentric abrasive elements, both in terms of offsetting center of mass and/or geometric eccentricity may also be employed.

Abstract: A terrestrial dwelling (1) including a floor (2) with at least one floor section (3) orientated substantially horizontally in use. The dwelling includes at least one wall (4), including at least one wall section (5) projecting substantially upwardly from the floor section (3). A dwelling support (6) is configured to at least partially elevate the floor section (3) above a terrain surface (15). A roof (7) with at least one roof section (8) is attached to an upper portion of said wall (4) wherein the dwelling (1) is configured to provide at least partial atmospheric transparency to at least partially allow atmospheric elements including light incident on the dwelling (1) above the floor (2) to reach the terrain surface (15) under the dwelling (1).

Abstract: The present invention is directed in various methods, devices and systems relating to rotational atherectomy. More specifically, an oscillating driver is connected to a drive shaft, or torque transfer tube, with abrasive element mounted thereon. The result provides a rotational working diameter for the rotating abrasive element that is larger than its resting diameter. Generally, the preferred abrasive element is concentric in profile and/or with center of mass collinear with the drive shaft's rotational axis. However, eccentric abrasive elements, both in terms of offsetting center of mass and/or geometric eccentricity may also be employed.

Abstract: To predict which Hepatitis C patients are at high-risk for disease progression or adverse health outcomes, baseline characteristics are measured for patients as well as longitudinal data, including clinical, laboratory and/or biopsy results, which may be collected periodically in follow-up visits with a healthcare professional. A machine learning engine may predict whether a patient is at high-risk for disease progression or adverse health outcomes based on the baseline characteristics and the longitudinal data for the patient.

Abstract: An elapsed time indicator (2), comprises an activator arrangement (25) comprising a fluid reservoir (20) and a conduit (22) configured to provide a predetermined flow rate of fluid (21) along the conduit (22). The elapsed time indicator (2) further comprises a visual display arrangement (18) configured to change appearance on exposure to the fluid (21). The conduit (22) connects the fluid reservoir (20) to the visual display arrangement (18). The activator arrangement (25) is configured to release fluid (21) from the fluid reservoir (20) in response to an activation event to permit the fluid (21) to flow.

Abstract: A terrestrial dwelling (1) including a floor (2) with at least one floor section (3) orientated substantially horizontally in use. The dwelling includes at least one wall (4), including at least one wall section (5) projecting substantially upwardly from the floor section (3). A dwelling support (6) is configured to at least partially elevate the floor section (3) above a terrain surface (15). A roof (7) with at least one roof section (8) is attached to an upper portion of said wall (4) wherein the dwelling (1) is configured to provide at least partial atmospheric transparency to at least partially allow atmospheric elements including light incident on the dwelling (1) above the floor (2) to reach the terrain surface (15) under the dwelling (1).

Abstract: A method for identifying patients with a high risk of liver cancer development includes receiving patient data describing a plurality of patients and executing a patient identification module on the patient data to identify at least some of the plurality of patients as having a high risk of developing liver cancer. The patient identification module is generated based on an application of machine learning techniques to a training data set, and the patient identification module is validated based on both the training data set and an external validation data set. Further, the method includes generating a grouping of the plurality of patients based on the identification of the at least some of the plurality of patients.

Abstract: The present invention is directed in various methods, devices and systems relating to rotational atherectomy. More specifically, an oscillating driver is connected to a drive shaft, or torque transfer tube, with abrasive element mounted thereon. The result provides a rotational working diameter for the rotating abrasive element that is larger than its resting diameter. Generally, the preferred abrasive element is concentric in profile and/or with center of mass collinear with the drive shaft's rotational axis. However, eccentric abrasive elements, both in terms of offsetting center of mass and/or geometric eccentricity may also be employed.

Abstract: The present invention is directed in various methods, devices and systems relating to rotational atherectomy. More specifically, an oscillating driver is connected to a drive shaft, or torque transfer tube, with abrasive element mounted thereon. The result provides a rotational working diameter for the rotating abrasive element that is larger than its resting diameter. Generally, the preferred abrasive element is concentric in profile and/or with center of mass collinear with the drive shaft's rotational axis. However, eccentric abrasive elements, both in terms of offsetting center of mass and/or geometric eccentricity may also be employed.

Abstract: Advanced communications features are provided in a mobile communications network having at least one mobile switching center and at least one mobile station subsystem. The mobile switching center and mobile station subsystem each communicate signaling messages according to a mobile signaling protocol.

Abstract: An elapsed time indicator (2), comprises an activator arrangement (25) comprising a fluid reservoir (20) and a conduit (22) configured to provide a predetermined flow rate of fluid (21) along the conduit (22). The elapsed time indicator (2) further comprises a visual display arrangement (18) configured to change appearance on exposure to the fluid (21). The conduit (22) connects the fluid reservoir (20) to the visual display arrangement (18). The activator arrangement (25) is configured to release fluid (21) from the fluid reservoir (20) in response to an activation event to permit the fluid (21) to flow.

Abstract: A method of using a variable set from complete blood counts and blood chemistry panels to generate a machine learned algorithm for determining the effectiveness of thiopurine treatment on inflammatory bowel disease (IBD) patients using CART, boosted trees, random forest classification, RuleFit and/or logistic regression analysis.

Abstract: Advanced communications features are provided in a mobile communications network having at least one mobile switching center and at least one mobile station subsystem. The mobile switching center and mobile station subsystem each communicate signaling messages according to a mobile signaling protocol.

Abstract: A method of using a variable set from complete blood counts and blood chemistry panels to generate a machine learned algorithm for determining the effectiveness of thiopurine treatment on inflammatory bowel disease (IBD) patients using CART, boosted trees, random forest classification, RuleFit and/or logistic regression analysis.

Abstract: Advanced communications features are provided in a mobile communications network having at least one mobile switching center and at least one mobile station subsystem. The mobile switching center and mobile station subsystem each communicate signaling messages according to a mobile signaling protocol. An indication is received that a half-duplex mobile communications session is to be initiated between a first mobile station subsystem and a second mobile station subsystem. The first and second mobile station subsystems include full-duplex communications apparatus for use in full-duplex mobile communications sessions. The half-duplex mobile communications session relies on the first and second mobile station subsystems, and all of the reliance is only on the full-duplex communications apparatus. Mobile communications telephone calls are established with the first mobile station subsystem and the second mobile station subsystem.

Abstract: The real time Ethernet protocol (RTEP) of the present invention offers improved speed and performance for an Ethernet network, while simultaneously enhancing the Ethernet's communication functionality. The RTEP provides a data frame, within the standard Ethernet protocol frame, containing information to support network functionality ordinarily associated with higher level protocol layers. The RTEP can guarantee delivery of messages as well as correct message sequence. The RTEP also supports IP subnetting, message piggybacking, Ethernet network sharing, and dynamic replacement of Ethernet stations. The present invention has particular application in conducting communications between one or more hosts and a telecommunications switching system.