Patents by Inventor Peter Hinckley

Peter Hinckley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step
    Patent number: 8263750
    Abstract: A method for purifying a protein using Protein A chromatography comprising a) absorbing the protein to Protein A immobilized on a solid support; b) removing contaminants by washing the immobilized Protein A containing the absorbed protein with a buffer comprising one or more chaotropic agents in combination with one or more hydrophobic modifiers and having a pH of at least 7.0; and c) eluting the protein from the Protein A immobilized on the solid support.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: September 11, 2012
    Assignee: Amgen Inc.
    Inventors: Abhinav A. Shukla, Peter Hinckley
  • Wash Buffer And Method Of Using
    Publication number: 20090306351
    Abstract: A method for purifying a protein using Protein A chromatography comprising a) absorbing the protein to Protein A immobilized on a solid support; b) removing contaminants by washing the immobilized Protein A containing the absorbed protein with a buffer comprising one or more chaotropic agents in combination with one or more hydrophobic modifiers and having a pH of at least 7.0; and c) eluting the protein from the Protein A immobilized on the solid support.
    Type: Application
    Filed: March 16, 2007
    Publication date: December 10, 2009
    Applicant: Amgen Inc.
    Inventors: Abhinav A. Shukla, Peter Hinckley