Abstract: An electrically conductive connection between at least two electrically conductive stacks of at least partially structured, metal foils which form a large number of channels through which a fluid may flow, comprising at least one electrically conductive rod element which passes through the at least two stacks, wherein a spacer element is arranged on the at least one rod element and between the at least two stacks, the two stacks being arranged at a distance from one another by the spacer element; wherein an arrangement comprising the at least two stacks, the at least one rod element and the spacer element is clamped by at least one clamping element.

Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: Compounds active on protein kinases and methods for regulating protein kinase pathways are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: The present disclosure provides methods of using protein kinase inhibitors for treating diseases and conditions, including diseases and conditions associated with activity of any protein kinase selected from Fms protein kinase including any mutations thereof, Kit protein kinase any mutations thereof, Flt-3 protein kinase any mutations thereof and combinations thereof.

Abstract: Compounds active on protein kinases and methods for regulating protein kinase pathways are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: A honeycomb body includes at least a housing and a honeycomb structure having a plurality of channels. The honeycomb structure is formed of at least one at least partially structured metallic layer that forms connecting points fixing the honeycomb structure. At most 20% of inner contact points in a cross section of the honeycomb structure form a connection point, and the connection points are disposed at a distance from each other in such a way that respective connection-free regions of the same size surround each of the connection points. An exhaust-gas purification unit and a motor vehicle are also provided.

Abstract: The invention relates to a particle filter (1) for an exhaust gas system (2), and to a method for producing a particle filter. The particle filter (1) comprises a plurality of flow channels (5), which extend from a first end face (6) towards a second end face (7) and which are separated from one another by porous channel walls (8). On the end faces (6, 7), the flow channels (5) each have mutual closing means (9) such that an exhaust gas (10) enters a flow channel (5) that is open on the first end face (6), flows through the channel wall (8), and escapes from the particle filter (1) by way of an adjacent flow channel (5) that is open on the second end face (7).

Abstract: The present disclosure provides methods of using protein kinase inhibitors for treating diseases and conditions, including diseases and conditions associated with activity of any protein kinase selected from Fms protein kinase including any mutations thereof, Kit protein kinase any mutations thereof, Flt-3 protein kinase any mutations thereof and combinations thereof.

Abstract: The invention relates to a honeycomb body with an electric heating device. The electric heating device includes at least one electrically insulating heating wire which is fixed by a pin assembly to a front side of a honeycomb body. The electrically insulated heating wire is positioned at a distance of at least five times and a maximum of fifteen times that of the wire diameter.

Abstract: An electrically heatable honeycomb body assembly includes an electrical connection of sheet metal layers at a connection pin. A honeycomb body has a metal casing with an inner periphery, through which the connection pin is led in a bushing and electrically insulated. The sheet metal layers are alternately coarsely structured and finely structured or smooth sheets together forming a stack with uppermost and lowermost layers and channels for an axial gas flow between the layers. The connection pin runs radially approximately perpendicular to the layers and is metallically connected to at least two or all of the layers through at least one intermediate piece. The uppermost sheet metal layer preferably runs approximately parallel to the metal casing over at least 35% of the inner periphery and is separated therefrom only by an air gap. Simple production of an operationally safe and very uniformly electrically heatable honeycomb body is provided.

Abstract: An exhaust-gas treatment device includes a honeycomb body wound and/or stacked with at least partially structured sheet-metal layers forming channels through which an exhaust gas can flow in axial direction from an inlet side to an outlet side. A first section of the sheet-metal layers ends flush at a first end surface associated with at least one of the sides and a second section of the sheet-metal layers ends at a second end surface associated with at least one of the sides. A spacing is provided between the first and second end surfaces because a first axial length of the first section is greater than a second axial length of the second section. The spacing forms a receptacle receiving a heating body, producing a simple electrically heatable exhaust-gas treatment device into which a heating body can be integrated during or after production of the honeycomb body.

Abstract: A method for influencing a fluid flow in a fluid line is provided. The fluid line has a wall and a honeycomb body arranged in the fluid line with a fluid inlet side and a fluid outlet side. The honeycomb body has a honeycomb structure with a cross section area and with ducts through which the fluid flow can flow from the fluid inlet side to the fluid outlet side. The honeycomb body has an outer boundary. The honeycomb structure has a circumferential outer zone close to the boundary and a central zone arranged within the outer zone. The outer zone includes at most 70% of the cross section area. The method includes providing the fluid flow upstream of the honeycomb body, entry of the fluid flow into the honeycomb body, and at least partial redirection of the fluid flow outwards in a radial direction.

Abstract: A honeycomb body for exhaust gas aftertreatment includes a first end face, a second end face, a central axis that penetrates the two end faces and a length. The honeycomb body has at least one at least partially structured metallic layer which is disposed about the central axis. A structure of the at least one metallic layer has elevations and depressions which extend at least over part of the length of the honeycomb body and run obliquely to the central axis. At least one metallic connecting strip is provided between adjacent regions of the at least one metallic layer. The metallic connecting strip is shorter than the length of the honeycomb body and forms a brazed connection or welded connection to the adjacent regions. A method for producing such a honeycomb body and a motor vehicle having the honeycomb body are also provided.

Abstract: A device for treating a gas stream, especially an exhaust-gas stream of an internal combustion engine, includes at least one radial chamber radially conducting the gas stream and extending substantially radially from a central region to an outer collecting chamber. First and second, preferably parallel, substantially disk-shaped walls delimit the chamber. Electrodes project from the first wall into the chamber. The first wall is formed of electrically insulating material having the electrodes fastened therein and electrically interconnected by electrical conductors in or on the insulating material. Two or more chambers may be disposed, axially in series, around the central region. Very effective treatment of exhaust gas with an electric field for ionization or generating a plasma can be provided over a relatively short structural length in a flow direction. Electric fields running transversely to the flow direction provide new possibilities for selecting various parameters of the treatment device.

Abstract: The present disclosure provides methods of using protein kinase inhibitors for treating diseases and conditions, including diseases and conditions associated with activity of any protein kinase selected from Fms protein kinase including any mutations thereof, Kit protein kinase any mutations thereof, Flt-3 protein kinase any mutations thereof and combinations thereof.

Abstract: A honeycomb body includes sheet metal layers forming a central current path to a radial connecting pin. A metal casing has an inner periphery and a feedthrough guiding and insulating the pin. The layers are alternate coarsely structured and finely structured or smooth sheets forming a stack with uppermost and lowermost layers forming axial gas channels. The pin is metallically connected to two or all of the layers directly or through an intermediate piece by an electrically conductive or welded connection. The current path has an electrical resistance per unit length in the connection region being greater than an average electrical resistance per unit length in the stack. The uppermost layer runs approximately parallel to the casing over 35% or 40% of the inner periphery and is separated from the casing by an air gap. Simple manufacture of a highly uniform, reliably operating, electrically heatable honeycomb body is thus possible.

Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: A method for operating an exhaust gas treatment device including an electric heater for heating an exhaust gas flow in the exhaust gas treatment device and/or a surface in the exhaust gas treatment device and a feed point for feeding an additive into the exhaust gas treatment device to impinge upon the electric heater, includes supplying additives to the feed point, determining an operational state of the exhaust gas treatment device, in which deposits can impinge upon the electric heater, using at least one state variable, determining a cycle frequency in dependence on the operating state when the operating state lies in a predetermined operating state range, and cyclically activating and deactivating the electric heater using the determined cycle frequency when the determined operating state lies in the predetermined operating state range. A motor vehicle having the exhaust-gas treatment device is also provided.

Abstract: The present disclosure provides methods of using protein kinase inhibitors for treating diseases and conditions, including diseases and conditions associated with activity of any protein kinase selected from Fms protein kinase including any mutations thereof, Kit protein kinase any mutations thereof, Flt-3 protein kinase any mutations thereof and combinations thereof.

Abstract: A method for operating a dosing unit for dosing reducing agent into an exhaust gas treatment device for purifying the exhaust gases of an internal combustion engine, includes providing the dosing unit with at least one delivery pump, at least one injector and a line section for conducting reducing agent from the delivery pump to the injector. The dosing unit is first operated for dosing reducing agent into the exhaust gas treatment device. Then, the dosing unit is shut off. Subsequently, a first pressure is maintained in the line section for at least a first time period, with the first pressure exceeding atmospheric pressure. A motor vehicle having the dosing unit is also provided.