Abstract: The invention relates to an in vitro process for diagnosing cystic fibrosis, which brings into play conditions, particularly temperatures at which some of the hydrolases released by the cells from the individual under study, particularly .alpha.-mannosidase and acid phosphatase, are subject to greater inactivation kinetics, when the cells originated from individuals affected by the disease or capable of transmitting it, than when said cells were from healthy people. The process thus consists of maintaining such cells, either in natural biological media or in culture media at a temperature within said intervals for a time long enough to appreciate the degree or kinetics of inactivation which can then be correlated to the fact that the individual is either healthy or affected by the disease or liable of transmitting it.

Abstract: The invention relates to novel processes and devices for the analysis of samples of very small volume.The process consists in taking definite amounts of reagents by capillarity on the end of fine rods, then recovering the amounts taken by centrifugation, the reagents being projected to the bottom of the same container. The device comprises elements for taking up, associated with a container able to be centrifuged.The process and the device are particularly useful for enzymatic micro-analyses.