Patents by Inventor Peter J. Gengo

Peter J. Gengo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
    Patent number: 8476280
    Abstract: Compositions and methods for treatment of a urinary tract dysfunction by administering to a subject in need of such treatment a pharmaceutical composition including a delta opioid receptor agonist in an amount effective to reduce the effects of the urinary tract dysfunction. The compositions may further include an additional active agent that is used to treat urinary tract dysfunctions, e.g., alpha-adrenergic agonists, anticholinergics, alpha-adrenergic antagonists and tricyclic antidepressants.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: July 2, 2013
    Assignee: Versi Group, LLC
    Inventors: Kwen-Jen Chang, Peter J. Gengo, Kestutis P. Biciunas, Xin Ma, William Pendergast, Shyi-Tai Jan
  • METHOD FOR TREATING HEART FAILURE WITH STRESSCOPIN-LIKE PEPTIDES
    Publication number: 20110105397
    Abstract: The present invention relates to novel methods of treating heart failure comprising administering an amount of stresscopin-like peptide to a subject in need thereof; and substantially maintaining the amount of said peptide present in the plasma of said subject at a concentration resulting in a therapeutic benefit without a substantial increase in the heart rate of said subject. The method involves the use of stresscopin-like peptides that are selective corticotrophin releasing hormone receptor type 2 (CRHR2) agonists.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 5, 2011
    Inventors: Peter J. Gengo, Hani N. Sabbah, Nigel P. Shankley
  • CARDIOPROTECTIVE DELTA OPIOID RECEPTOR AGONISTS AND METHODS OF USING SAME
    Publication number: 20080125443
    Abstract: The present invention relates to compositions and methods of treatment for cardioprotection through the use of non-peptidic delta opioid receptor agonist compound(s) that mediate cardioprotective effects of ischemic preconditioning. The compounds are used to reduce injury associated with ischemia and reperfusion of cardiac tissue. Further, the compounds may be used in solutions preserving the viability of an isolated organ.
    Type: Application
    Filed: November 27, 2007
    Publication date: May 29, 2008
    Inventors: Kwen-Jen Chang, William Pendergast, Peter J. Gengo, Xin Ma
  • Cardioprotective delta opioid receptor agonists and methods of using same
    Patent number: 7314880
    Abstract: The present invention relates to compositions and methods of treatment for cardioprotection through the use of non-peptidic delta opioid receptor agonist compound(s) that mediate cardioprotective effects of ischemic preconditioning. The compounds are used to reduce injury associated with ischemia and reperfusion of cardiac tissue. Further, the compounds may be used in solutions preserving the viability of an isolated organ.
    Type: Grant
    Filed: December 31, 2003
    Date of Patent: January 1, 2008
    Assignee: Mount Cook Biosciences, Inc.
    Inventors: Kwen-Jen Chang, William Pendergast, Peter J. Gengo, Xin Ma
  • Method of treating depression with delta receptor agonist compounds
    Patent number: 7030124
    Abstract: Methods for treatment of depression or other affective mood disorders, such as bipolar manic depression or seasonal affective disorder, are disclosed by administration to a subject suffering or susceptible to same, of therapeutically effective diarylpiperazine compounds as herein described.
    Type: Grant
    Filed: October 29, 2002
    Date of Patent: April 18, 2006
    Assignee: Ardent Pharmaceuticals, Inc.
    Inventors: Kwen-Jen Chang, William Pendergast, Peter J. Gengo
  • Cardioprotective delta opioid receptor agonists and methods of using same
    Publication number: 20040171622
    Abstract: The present invention relates to compositions and methods of treatment for cardioprotection through the use of non-peptidic delta opioid receptor agonist compound(s) that mediate cardioprotective effects of ischemic preconditioning. The compounds are used to reduce injury associated with ischemia and reperfusion of cardiac tissue. Further, the compounds may be used in solutions preserving the viability of an isolated organ.
    Type: Application
    Filed: December 31, 2003
    Publication date: September 2, 2004
    Inventors: Kwen-Jen Chang, William Pendergast, Peter J. Gengo, Xin Ma
  • Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
    Publication number: 20040002503
    Abstract: Compositions and methods for treatment of a urinary tract dysfunction by administering to a subject in need of such treatment a pharmaceutical composition including a delta opioid receptor agonist in an amount effective to reduce the effects of the urinary tract dysfunction. The compositions may further include an additional active agent that is used to treat urinary tract dysfunctions, e.g., alpha-adrenergic agonists, anticholinergics, alpha-adrenergic antagonists and tricyclic antidepressants.
    Type: Application
    Filed: May 8, 2003
    Publication date: January 1, 2004
    Inventors: Kwen-Jen Chang, Peter J. Gengo, Kestutis P. Biciunas, Xin Ma, William Pendergast, Shyi-Tai Jan
  • Method of treating depression with delta receptor agonist compounds
    Publication number: 20030144299
    Abstract: Compositions and methods for treatment of depression or other affective mood disorders or pathological mental and/or emotional states, by administration to a subject suffering or susceptible to same, of therapeutically effective delta receptor agonist compound(s), optionally in combination with other mood disorder-combating agents.
    Type: Application
    Filed: October 29, 2002
    Publication date: July 31, 2003
    Inventors: Kwen-Jen Chang, William Pendergast, Peter J. Gengo