Patents by Inventor Peter J. Giddings

Peter J. Giddings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of penicillanic acid derivatives
    Patent number: 4347182
    Abstract: The compound 6-.beta.-chloropenicillanic acid can be prepared in substantially pure form and is a .beta.-lactamase inhibitor which may be used to enhance the effectiveness of penicillins acid cephalosporins against .beta.-lactamase producing lacteria.The process comprises the reaction of a compound of the formula: ##STR1## wherein R.sup.X is hydrogen or a carboxyl-blocking group and R is an aryl group, with a trialkyl tin hydride or a triaryl tin hydride or a dialkyl tin dihydride and optionally removing any carboxyl-blocking group R.sup.X, and/or oxidizing the atoms to an SO or SO.sub.2 ; and/or esterifying a salt of the acid to yield an in-vivo hydrolysable ester.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: August 31, 1982
    Assignee: Beecham Group Limited
    Inventors: Peter J. Giddings, David I. John, Eric J. Thomas