Patents by Inventor Peter J. Islip

Peter J. Islip has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aryl derivatives
    Patent number: 5036157
    Abstract: Novel compounds of formula (I)Ar--(L--Ar').sub.q --(X).sub.k --(Y).sub.p --Q (I)wherein:k, p and q are independently 0 or 1;Ar represents either:(i) naphthyl, tetrahydronaphthyl, pyridyl or(ii) phenyl, optionally substituted,L is selected from --(CH.sub.2).sub.r -- (where r is 1-4), --O--, --CH.sub.2 O--, --CH.sub.2 S--, --OCH.sub.2 --, --CONH--, --NHCO--, --CO-- and --CH.sub.2 NH--, and,Ar' represents phenylene, thienylene or pyridylene optionally substituted,X represents oxygen, sulphur or carbonyl,Y is C.sub.1-10 alkylene or C.sub.1-10 alkenylene;Q represents a non-cyclic moiety selected from groups of formula ##STR1## in which one of m and n is 0 and the other is 1, R.sup.1 and R.sup.2 is selected from hydrogen, C.sub.1-4 alkyl, amino, C.sub.1-4 alkylamino, di-C.sub.1-4 alkylamino, C.sub.5-7 cycloalkylamino, C.sub.5-7 cycloalkyl (C.sub.1-4 alkyl) amino, anilino, N-C.sub.
    Type: Grant
    Filed: March 10, 1987
    Date of Patent: July 30, 1991
    Assignee: Burroughs Wellcome Co.
    Inventors: Geoffrey Kneen, William P. Jackson, Peter J. Islip, Peter J. Wates
  • Method of treating inflammation
    Patent number: 4977188
    Abstract: Novel hydroxamic acid and derivatives of formula (I)Ar--(L--Ar').sub.q --(X).sub.k --(Y).sub.p --Q (I)are disclosed. Also described are their preparation, compositions containing them and their use.
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: December 11, 1990
    Assignee: Burroughs Wellcome Co.
    Inventors: Geoffrey Kneen, William P. Jackson, Peter J. Islip, Peter J. Wates
  • N-(3-phenoxycinnamyl)acetohydroxamic acid
    Patent number: 4738986
    Abstract: Novel compounds of formula (I)Ar--(L--Ar').sub.q --(X).sub.k --(Y).sub.p --Q (I)wherein:k, p and q are independently 0 or 1;Ar represents either:(i) naphthyl, tetrahydronaphthyl, pyridyl or(ii) phenyl, optionally substituted,L is selected from --(CH.sub.2).sub.r -- (where r is 1-4), --O--, --CH.sub.2 O--, --CH.sub.2 S--, --OCH.sub.2 --, --CONH--, --NHCO--, --CO-- and --CH.sub.2 NH--, and,Ar' represents phenylene, thienylene or pyridylene optionally substituted,X represents oxygen, sulphur or carbonyl,Y is C.sub.1-10 alkylene or C.sub.1-10 alkenylene;Q represents a non-cyclic moiety selected from groups of formula ##STR1## in which one of m and n is 0 and the other is 1, R.sup.1 and R.sup.2 is selected from hydrogen, C.sub.1-4 alkyl, amino, C.sub.1-4 alkylamino, di-C.sub.1-4 alkylamino, C.sub.5-7 cycloalkylamino, C.sub.5-7 cycloalkyl (C.sub.1-4 alkyl) amino, anilino, N-C.sub.
    Type: Grant
    Filed: March 10, 1987
    Date of Patent: April 19, 1988
    Assignee: Burroughs Wellcome Co.
    Inventors: Geoffrey Kneen, William P. Jackson, Peter J. Islip, Peter J. Wates
  • Heterocyclic chemicals, their preparation and use
    Patent number: 4379156
    Abstract: Compounds of formula (III): ##STR1## wherein R.sup.5 is a single substituent in position 2 or 3 of the phenyl ring and when in the 2-position R.sup.5 is a chlorine atom, a methyl group or a nitro group; and R.sup.6 is a hydrogen atom or a CO.CH.sub.3 group may be prepared by methods analogous to those known in the art, for example, by reaction of the corresponding nitrothiazolyl benzamide with the corresponding halo(di)acetamide. The compounds of formula (III) have schistosomicidal activity and may be administered either as the compound alone or as a pharmaceutical formulation.
    Type: Grant
    Filed: December 22, 1980
    Date of Patent: April 5, 1983
    Assignee: Burroughs Wellcome Co.
    Inventors: Peter J. Islip, Mirjana V. Bogunovic