Abstract: Disclosed are monoclonal antibodies, antigen binding fragments, and bi-specific antibodies that specifically bind a coronavirus spike protein, such as SARS-CoV-2. Also disclosed is the use of these antibodies for inhibiting a coronavirus infection, such as a SARS-CoV-2 infection. In addition, disclosed are methods for detecting a coronavirus, such as SARS-CoV-2, in a biological sample, using the disclosed antibodies.

Abstract: A method of fabricating an object, comprising direct depositing a first layer of first object material on a support substrate electrode; applying a conductive agent material onto the first layer; direct depositing a first layer of charged powder onto the first layer on the support substrate electrode, to form a first powder layer on the first layer on the support substrate electrode. Multiple powder layers may be direct deposited on the first layer. The method may be further comprised of fusing the powder layer(s) to form a first fused layer on the support substrate electrode. A related object fabrication apparatus is also disclosed.

Abstract: A method of fabricating an object, comprising depositing a first layer of first object material on a support substrate electrode; applying a conductive agent material onto the first layer; depositing a first layer of charged powder on an intermediate substrate; conveying the first layer of charged powder on the intermediate substrate proximate to the first layer of first object material; and applying a transferring electric field to cause transfer of the first layer of charged powder from the intermediate substrate onto the first layer on the support substrate electrode, to form a first powder layer on the first layer on the support substrate electrode. Multiple powder layers may be deposited on the first layer. The method may be further comprised of fusing the powder layer(s) to form a first fused layer on the support substrate electrode. A related object fabrication apparatus is also disclosed.

Abstract: A method of fabricating an object, comprising depositing a first layer of first object material on a support substrate electrode; applying a conductive agent material onto the first layer; depositing a first layer of charged powder on an intermediate substrate; conveying the first layer of charged powder on the intermediate substrate proximate to the first layer of first object material; and applying a transferring electric field to cause transfer of the first layer of charged powder from the intermediate substrate onto the first layer on the support substrate electrode, to form a first powder layer on the first layer on the support substrate electrode. Multiple powder layers may be deposited on the first layer. The method may be further comprised of fusing the powder layer(s) to form a first fused layer on the support substrate electrode. A related object fabrication apparatus is also disclosed.

Abstract: An apparatus for forming a part, comprising a substrate for holding the part during forming; a transport web; a web delivery system; a powder generation system configured to deposit a portion of powder on a portion of the web delivered by the delivery system; a sintering station configured to sinter the portion of powder on the delivered portion of the transport web; and a transfer station configured to transfer the sintered portion of the powder from the transport web to a partially formed portion of the part and join the sintered portion of the powder to the partially formed part. Additionally, a method for making a part comprising depositing a first portion of a powder on a transport web substrate; sintering the first portion of powder on the web substrate; and joining the sintered portion of the powder to the support substrate to form a first layer of the part.

Abstract: A method is disclosed for improving the productivity of digitally fabricated 3D objects with the same or different shape and material composition. The improved productivity is enabled by the incorporation of multiple build platforms and multiple objects per build platform within a 3D object fabrication apparatus. Some 3D manufacturing processes such as those based on electrophotography require a wait time to condition the build object before the next layer of build and support material can be applied. Under these fabrication conditions, the utilization of multiple build platforms in the 3D object manufacturing process effectively minimizes the wait time between layer deposition so that the productivity for fabricating 3D objects is improved. Furthermore, the incorporation of an additional adjacent set of multiple platforms enables rapid changeover when the fabrication of one set of 3D objects is completed on an adjacent set of build platforms.

Abstract: A method of fabricating an object, comprising depositing a first layer of first object material on a support substrate electrode; applying a conductive agent material onto the first layer; depositing a first layer of charged powder on an intermediate substrate; conveying the first layer of charged powder on the intermediate substrate proximate to the first layer of first object material; and applying a transferring electric field to cause transfer of the first layer of charged powder from the intermediate substrate onto the first layer on the support substrate electrode, to form a first powder layer on the first layer on the support substrate electrode. Multiple powder layers may be deposited on the first layer. The method may be further comprised of fusing the powder layer(s) to form a first fused layer on the support substrate electrode. A related object fabrication apparatus is also disclosed.

Abstract: A method is disclosed for improving the productivity of digitally fabricated 3D objects with the same or different shape and material composition. The improved productivity is enabled by the incorporation of multiple build platforms and multiple objects per build platform within a 3D object fabrication apparatus. Some 3D manufacturing processes such as those based on electrophotography require a wait time to condition the build object before the next layer of build and support material can be applied. Under these fabrication conditions, the utilization of multiple build platforms in the 3D object manufacturing process effectively minimizes the wait time between layer deposition so that the productivity for fabricating 3D objects is improved. Furthermore, the incorporation of an additional adjacent set of multiple platforms enables rapid changeover when the fabrication of one set of 3D objects is completed on an adjacent set of build platforms.

Abstract: A toner consists essentially of food-grade components. Because the toner consists essentially of food-grade components, it can be used to provide a coating or create an image on food products, including those intended for human or animal consumption.

Abstract: A method of fabricating an object, comprising depositing a first layer of first object material on a support substrate electrode; applying a conductive agent material onto the first layer; depositing a first layer of charged powder on an intermediate substrate; conveying the first layer of charged powder on the intermediate substrate proximate to the first layer of first object material; and applying a transferring electric field to cause transfer of the first layer of charged powder from the intermediate substrate onto the first layer on the support substrate electrode, to form a first powder layer on the first layer on the support substrate electrode. Multiple powder layers may be deposited on the first layer. The method may be further comprised of fusing the powder layer(s) to form a first fused layer on the support substrate electrode. A related object fabrication apparatus is also disclosed.

Abstract: A method is disclosed for improving the productivity of digitally fabricated 3D objects with the same or different shape and material composition. The improved productivity is enabled by the incorporation of multiple build platforms and multiple objects per build platform within a 3D object fabrication apparatus. Some 3D manufacturing processes such as those based on electrophotography require a wait time to condition the build object before the next layer of build and support material can be applied. Under these fabrication conditions, the utilization of multiple build platforms in the 3D object manufacturing process effectively minimizes the wait time between layer deposition so that the productivity for fabricating 3D objects is improved. Furthermore, the incorporation of an additional adjacent set of multiple platforms enables rapid changeover when the fabrication of one set of 3D objects is completed on an adjacent set of build platforms.

Abstract: An apparatus for forming a part, comprising a substrate for holding the part during forming; a transport web; a web delivery system; a powder generation system configured to deposit a portion of powder on a portion of the web delivered by the delivery system; a sintering station configured to sinter the portion of powder on the delivered portion of the transport web; and a transfer station configured to transfer the sintered portion of the powder from the transport web to a partially formed portion of the part and join the sintered portion of the powder to the partially formed part. Additionally, a method for making a part comprising depositing a first portion of a powder on a transport web substrate; sintering the first portion of powder on the web substrate; and joining the sintered portion of the powder to the support substrate to form a first layer of the part.

Abstract: An object fabricating apparatus is comprised of at least one charged powder cloud generating system, at least one electrode proximate to the powder cloud generating system and comprising at least one shaped slot, and a voltage supply in communication with each electrode to electrostatically modulate the flow of charged powder to a conductive substrate electrically biased to provide an electrostatic attraction of the charged powder to the substrate. An object fabricating method is also disclosed that uses the object fabricating apparatus.

Abstract: An object fabricating apparatus is comprised of at least one charged powder cloud generating system, at least one electrode proximate to the powder cloud generating system and comprising at least one shaped slot, and a voltage supply in communication with each electrode to electrostatically modulate the flow of charged powder to a conductive substrate electrically biased to provide an electrostatic attraction of the charged powder to the substrate. An object fabricating method is also disclosed that uses the object fabricating apparatus.

Abstract: Monochromatic or multichromatic images may be created on surfaces. The surface is moved to first, second and third stations. The surface is electrically biased, and powder is transferred to the surface electrostatically at the first station. The powder is fused or sintered selectively on the surface at the second station. Unfused or unsintered portions of the powder are removed from the surface at the third station.

Abstract: Monochromatic or multichromatic images may be created on surfaces. The surface is moved to first, second and third stations. The surface is electrically biased, and powder is transferred to the surface electrostatically at the first station. The powder is fused or sintered selectively on the surface at the second station. Unfused or unsintered portions of the powder are removed from the surface at the third station.

Abstract: Monochromatic or multichromatic images may be created on surfaces. The surface is moved to first, second and third stations. The surface is electrically biased, and powder is transferred to the surface electrostatically at the first station. The powder is fused or sintered selectively on the surface at the second station. Unfused or unsintered portions of the powder are removed from the surface at the third station.

Abstract: A method for manufacturing electrodes using an electrostatic deposition unit. In the first step of the process a mixture of magnetic carrier beads and a conductive powder is prepared in the sump of the deposition unit; the mixture forms a magnetic brush on the sleeve of the deposition unit. In the second step of the process, the substrate is positioned away from the magnetic brush to form an air gap. In the third step of the process, a voltage is applied between the substrate and the sleeve of the deposition unit in order to produce a large asymmetry between the magnetic brush and said substrate such that the electric field at the magnetic brush is at least 3.0 times as great as the electric field at the substrate. In the fourth step of the process, conductive powder is deposited onto the substrate.

Abstract: A method for manufacturing electrodes using an electrostatic deposition unit. In the first step of the process a mixture of magnetic carrier beads and a conductive powder is prepared in the sump of the deposition unit; the mixture forms a magnetic brush on the sleeve of the deposition unit. In the second step of the process, the substrate is positioned away from the magnetic brush to form an air gap. In the third step of the process, a voltage is applied between the substrate and the sleeve of the deposition unit in order to produce a large asymmetry between the magnetic brush and said substrate such that the electric field at the magnetic brush is at least 3.0 times as great as the electric field at the substrate. In the fourth step of the process, conductive powder is deposited onto the substrate.

Abstract: Monochromatic or multichromatic images may be created on surfaces. The surface is moved to first, second and third stations. The surface is electrically biased, and powder is transferred to the surface electrostatically at the first station. The powder is fused or sintered selectively on the surface at the second station. Unfused or unsintered portions of the powder are removed from the surface at the third station.