Patents by Inventor Peter J. O'Brien

Peter J. O'Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BILATERAL VAGUS NERVE STIMULATION
    Publication number: 20240139512
    Abstract: An example system includes a first lead configured to be positioned in or beside a left internal jugular vein (IJV) of a patient to deliver a first stimulation signal to a first vagus nerve, the first lead including one or more first segmented electrodes positioned on a distal portion of the first lead and a first anchoring mechanism; a second lead configured to be positioned in or beside a right IJV of the patient to deliver a second stimulation signal to a second vagus nerve, the second lead including one or more second segmented electrodes positioned on a distal portion of the second lead and a second anchoring mechanism; and circuitry configured to deliver electrical energy to the first lead to deliver the first stimulation signal and the second lead to deliver the second stimulation signal to provide bilateral stimulation to the first vagus nerve and the second vagus nerve.
    Type: Application
    Filed: October 28, 2022
    Publication date: May 2, 2024
    Inventors: Randal C. Schulhauser, Richard J. O'Brien, Scott R. Stanslaski, Mark P. Ashby, Avram Scheiner, Becky L. Dolan, William Valls, JR., David J. Miller, Varun Umesh Kashyap, Peter N. Braido, Lilian Kornet
  • METHODS AND REAGENTS FOR DETECTING SUSCEPTIBILITY TO GRAFT VERSUS HOST DISEASE OR TRANSPLANT RELATED MORTALITY
    Publication number: 20110171664
    Abstract: The present invention provides methods for determining the likelihood and/or severity of GvHD and the likelihood of the occurrence of transplant related mortality.
    Type: Application
    Filed: January 11, 2011
    Publication date: July 14, 2011
    Inventor: Peter J. O'Brien
  • Diagnosis for porcine malignant hyperthermia
    Patent number: 6001976
    Abstract: A purified DNA molecule comprises a DNA sequence of approximately 15.1 kb coding for normal or mutant RYR1 protein having a molecular weight of approximately 564,740 daltons. The DNA molecule has an endonuclease restriction map of FIG. 1 and a sequence of FIG. 2.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: December 14, 1999
    Assignee: University of Toronto Innovations Foundation and University of Guelph
    Inventors: David H. MacLennan, Peter J. O'Brien
  • Diagnosis for porcine malignant hyperthermia
    Patent number: 5358649
    Abstract: A purified DNA molecule comprises a DNA sequence of approximately 15.1 kb coding for normal or mutant RYR1 protein having a molecular weight of approximately 564,740 daltons. The DNA molecule has an endonuclease restriction map of FIG. 1 and a sequence of FIG. 2.
    Type: Grant
    Filed: March 15, 1993
    Date of Patent: October 25, 1994
    Assignees: University of Guelph, The University of Toronto Innovations Foundation
    Inventors: David H. MacLennan, Peter J. O'Brien