Patents by Inventor Peter J. O'Connor

Peter J. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4389410
    Abstract: Compounds of formula (II): ##STR1## wherein R is C.sub.1-20 alkyl; C.sub.3-8 cycloalkyl; C.sub.3-20 alkenyl; aralkyl; cycloalkylalkyl; heterocyclyl or heterocyclylalkyl; each being substituted with formyl; ##STR2## have activity against human and veterinary bacteria and mycoplasma. They may be produced by conventional methods and are used in conventional formulations.
    Type: Grant
    Filed: July 21, 1981
    Date of Patent: June 21, 1983
    Assignee: Beecham Group Limited
    Inventors: Peter J. O'Hanlon, Norman H. Rogers
  • Patent number: 4362743
    Abstract: Compounds of formula (II): ##STR1## in which Y represents ##STR2## and R.sub.0 represents a C.sub.2-20 alkyl, C.sub.3-8 cycloalkyl, C.sub.4-20 alkenyl, arakyl, cycloalkylalkyl, heterocyclyl or heterocyclylalkyl group, which is substituted by a hydroxyiminohydrazono- or semicarbazono group, have activity against human and veterinary bacteria and mycoplasma. They may be produced by conventional methods and are used in conventional formulations.
    Type: Grant
    Filed: July 31, 1981
    Date of Patent: December 7, 1982
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon, Graham Walker
  • Patent number: 4312867
    Abstract: Compounds of formula (II): ##STR1## Z represents a divalent radical derived from a C.sub.1-20 alkane, C.sub.3-8 cycloalkane, C.sub.2-20 alkene, arene, aralkane, cycloalkylalkane, heterocycle, or heterocylylalkane; and R.sup.x and R.sup.y are the same or different and each represent (a) hydrogen, or (b) C.sub.1-20 alkyl, C.sub.2-8 alkenyl, either of which may be optionally substituted with C.sub.3-7 cycloalkyl, halogen, carboxy, C.sub.1-6 alkoxycarbonyl, carbamyl, aryl, heterocyclyl, hydroxy, C.sub.1-6 alkanoyloxy, amino, mono- or di-(C.sub.1-6) alkylamino; or (c) C.sub.3-7 cycloalkyl optionally substituted with C.sub.1-6 alkyl; or (d) aryl; or (e) heterocyclyl; or (f) R.sup.x and R.sup.y together with the nitrogen atom to which they are attached represent a C.sub.5-7 heterocyclic ring, are useful as antibacterial and antimycoplasma agents.
    Type: Grant
    Filed: September 24, 1980
    Date of Patent: January 26, 1982
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Patent number: 4284570
    Abstract: This invention relates to antibacterial compounds and in particular to a class of esters which have antibacterial activity against certain Gram-positive and Gram-negative organisms, and also possess antimycoplasmal activity. The compounds are therefore of value in the treatment of human and veterinary infections.
    Type: Grant
    Filed: October 18, 1979
    Date of Patent: August 18, 1981
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Patent number: 4248887
    Abstract: This invention relates to antibacterial compounds and in particular to a class of esters which have antibacterial activity against certain Gram-positive and Gram-negative organisms, and also possess anti-mycoplasmal activity. The compounds are therefore of value in the treatment of human and veterinary infections.
    Type: Grant
    Filed: March 19, 1979
    Date of Patent: February 3, 1981
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Patent number: 4226880
    Abstract: A compound of formula (II), named pseudomonic acid C or a salt or ester thereof: ##STR1## has antibacterial and anti-mycoplasma activity, and can be produced either by fermentation of Pseudomonas fluorescens, or by de-oxygenation of pseudomonic acid A, the compound having an epoxide in place of the double bond. The compounds are therefore useful in the treatment of human and veterinary bacterial and mycoplasma-induced infections.
    Type: Grant
    Filed: May 24, 1979
    Date of Patent: October 7, 1980
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Patent number: 4222942
    Abstract: A process for the purification of pseudomonic acid, particularly suitable for isolating the compound when prepared by bacterial culture, comprises making a solution in an organic solvent of the acidic components of the crude preparation substantially free of the neutral components. The polarity of the organic solvent is adjusted so that the pseudomonic acid crystallizes. This may be achieved either by adding a non-polar diluent such as n-heptane to the solution for example in methyl iso-butyl ketone; or by employing a di-C.sub.1-6 alkyl ether in which the acidic components dissolve and then crystallize out.
    Type: Grant
    Filed: September 29, 1978
    Date of Patent: September 16, 1980
    Assignee: Beecham Group Limited
    Inventors: Peter J. O'Hanlon, Maurice C. Woodford, Norman H. Rogers
  • Patent number: 4205002
    Abstract: A compound of formula (II), named pseudomonic acid C or a salt or ester thereof: ##STR1## has antibacterial and anti-mycoplasma activity, and can be produced either by fermentation of Pseudomonas fluorescens, or by de-oxygenation of pseudomonic acid A, the compound having a epoxide in place of the double bond. The compounds are therefore useful in the treatment of human and veterinary bacterial and mycoplasma-induced infections.
    Type: Grant
    Filed: October 27, 1978
    Date of Patent: May 27, 1980
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Patent number: 4062126
    Abstract: A mirror or other target-sight element in a military vehicle is subject to oticeable vibration or dislocation relative to inertial space as the vehicle moves over rough terrain. To prevent such vibration or dislocation the mirror is driven by a torque motor that is controlled by a gyroscope that mechanically senses these mirror dislocations. The demodulated gyroscope output signal is amplified and applied to the torque motor, which thereby makes the correct repositionment of the mirror to keep the reflected image in a generally stable position in spite of terrain disturbances. The present invention contemplates a second gyroscope also responsive to vehicle pitch movements. The demodulated output signal of this second gyroscope is applied to a zero cross over detector, which produces a square wave output signal substantially in phase with the signal from the first gyroscope.
    Type: Grant
    Filed: November 8, 1976
    Date of Patent: December 13, 1977
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Peter J. O'Hara, Louis P. De Leo