Patents by Inventor Peter J.R. Ebert

Peter J.R. Ebert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-SARS-COV-2 ANTIGEN ANTIBODIES AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20230382979
    Abstract: Provided are antibodies that specifically bind a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antigen. Nucleic acids that encode one or both of the variable chain polypeptides of an antibody of the present disclosure are also provided, as are cells that include such nucleic acids. Also provided are compositions that include the antibodies of the present disclosure, including in some instances, pharmaceutical compositions. Methods of making and using the antibodies of the present disclosure are also provided. In certain aspects, provided are methods that include administering to an individual in need thereof, e.g., an individual having or suspected of having a SARS-CoV-2 infection, a therapeutically effective amount of an antibody of the present disclosure.
    Type: Application
    Filed: October 29, 2021
    Publication date: November 30, 2023
    Inventors: Erik Yusko, Peter J. R. Ebert, Amy Gilbert, Gladys Keitany, Mark Klinger, Ben Rubin
  • Determining WT-1-Specific T Cells and WT-1 Specific T Cell Receptors (TCRS)
    Publication number: 20230042101
    Abstract: The invention is directed to methods for determining antigen-specific T cells generally and to T cell receptors which bind an epitope of the Wilms' tumor antigen-1 (WT1) protein specifically. The disclosure also provides polynucleotides encoding the TCRs, engineered cells exogenously expressing the TCRs, and methods of making and using the TCRs and/or cells expressing the TCRs.
    Type: Application
    Filed: July 14, 2022
    Publication date: February 9, 2023
    Inventors: Marcos E. Milla, Mark Klinger, Peter J.R. Ebert, Timothy L. Hayes, Edward J. Osborne, Joyce K. Hu
  • Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)
    Patent number: 11390921
    Abstract: The invention is directed to methods for determining antigen-specific T cells generally and to T cell receptors which bind an epitope of the Wilms' tumor antigen-1 (WT1) protein specifically. The disclosure also provides polynucleotides encoding the TCRs, engineered cells exogenously expressing the TCRs, and methods of making and using the TCRs and/or cells expressing the TCRs.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: July 19, 2022
    Assignee: Adaptive Biotechnologies Corporation
    Inventors: Marcos E. Milla, Mark Klinger, Peter J. R. Ebert, Timothy Lee Hayes, Edward J. Osborne, Joyce K. Hu
  • DETERMINING WT-1 SPECIFIC T CELLS AND WT-1 SPECIFIC T CELL RECEPTORS (TCRS)
    Publication number: 20180282808
    Abstract: The invention is directed to methods for determining antigen-specific T cells generally and to T cell receptors which bind an epitope of the Wilms' tumor antigen-1 (WT1) protein specifically. The disclosure also provides polynucleotides encoding the TCRs, engineered cells exogenously expressing the TCRs, and methods of making and using the TCRs and/or cells expressing the TCRs.
    Type: Application
    Filed: June 13, 2018
    Publication date: October 4, 2018
    Inventors: Marcos E. Milla, Mark Klinger, Peter J.R. Ebert, Timothy Lee Hayes, Edward J. Osborne, Joyce K. Hu