Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.

Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.

Abstract: The invention relates to condensed tricyclic benzimidazoles of formula (I) in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.

Abstract: The invention relates to a process for the preparation of (S)-glyceraldehyde acetonide in aqueous solution from 3,4-O-isopropylidene-L-threonic acid or a salt thereof in aqueous solution, and hypochlorite in aqueous solution wherein the aqueous hypochlorite solution has a pH>7.5 and wherein during addition of at least 0.1 molar equivalents of hypochlorite based on the amount of 3,4-O-isopropylidene-L-threonic acid, an acid solution is not simultaneously added. The invention also relates to a process according to the invention, wherein 3,4-O-isopropylidene-L-threonic acid or a salt thereof is prepared from 5,6-O-isopropylidene-L-ascorbic acid or a salt thereof in the presence of H2O2 and a base in a manner known per se, wherein excess H2O2 is optionally removed by catalase.

Abstract: The present invention relates to 8-substituted imidazopyridines of a certain formula (1) in which the substitutents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.

Abstract: A device (1) having a panel (3) and/or a supporting mechanism (5) consisting of thin, flexible material that can be rolled up itself. This flexibility reduces greatly the chance of damage. To make this flexible mechanism support the unrolled display, the structure is curved in the direction perpendicular to the unrolling direction.

Abstract: The invention relates to compounds of the formula (1) where the substituents and symbols are as defined in the description. The compounds are valuable intermediates for preparing active pharmaceutical ingredients.

Abstract: The invention relates to cyclic benzimidazoles of formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.

Abstract: The invention relates to a method for transferring a pattern from a stamping surface (31) of a stamp (30) to a receiving surface (21) of a substrate (20). The pattern is transferred to the receiving surface (21) by successively bringing portions of the pattern within such a range of the receiving surface (21) during a certain period, that the pattern is locally transferred from the stamping surface (31) to the receiving surface (21). The individual portions can be moved by means of individual actuators (50). By applying the method, the transfer of the pattern can be performed according to a wave, which is for example ring-shaped, moving from the center of the receiving surface (21) to the circumference, or linear, moving from side of the receiving surface (21) to an opposite side.

Abstract: The present invention relates to methods for the preparation of diastereomerically pure (3R,3aS,6aR)hexahydro-furo[2,3-b]furan-3-ol as well as a novel intermediate, (3aR,4S,6aS)4-methoxy-tetrahydro-furo[3,4-b]furan-2-one for use in said methods. More in particular the invention relates to a stereoselective method for the preparation of diastereomerically pure (3R,3aS,6aR)hexahydro-furo[2,3-b]furan-3-ol, as well as methods for the crystallization of (3aR,4S,6aS)4-methoxy-tetrahydro-furo[3,4-b]furan-2-one and for the epimerization of (3aR,4R,6aS)4-methoxy-tetrahydro-furo[3,4-b]-furan-2-one to (3aR,4S,6aS)4-methoxy-tetrahydro-furo[3,4-b]furan-2-one.

Abstract: The invention relates to a process for the preparation of (S)-glyceraldehyde acetonide in aqueous solution from 3,4-O-isopropylidene-L-threonic acid or a salt thereof in aqueous solution, and hypochlorite in aqueous solution wherein the aqueous hypochlorite solution has a pH >7.5 and wherein during addition of at least 0.1 molar equivalents of hypochlorite based on the amount of 3,4-O-isopropylidene-L-threonic acid, an acid solution is not simultaneously added. The invention also relates to a process according to the invention, wherein 3,4-O-isopropylidene-L-threonic acid or a salt thereof is prepared from 5,6-O-isopropylidene-L-ascorbic acid or a salt thereof in the presence of H2O2 and a base in a manner known per se, wherein excess H2O2 is optionally removed by catalase.

Abstract: A process for preparation of a compound with enhanced optical purity is disclosed wherein a mixture of the enantiomers of a chiral amine is brought into contact with an enzyme having peptide deformylase activity with a bivalent metal ion as a cofactor.

Abstract: The present invention relates to a method for the preparation of hexahydro-furo[2,3-b]furan-3-ol as well as novel intermediates for use in said method. More in particular the invention relates to a stereoselective method for the preparation of hexahydro-furo[2,3-b]furan-3-ol, and to a method amenable to industrial scaling up.

Abstract: A method is proposed for measuring water permeability of substrates (1). A reactive compound (Ca, Ba) which reacts with a diffusing material, e.g. water, is applied on the substrate and the change in time of transmissivity, reflectivity of the layer is monitored in time.

Abstract: The invention relates to a method of controlling a display screen, particularly a foil display built up of a number of lines, the display screen comprising at least one light source, a movable element, and selection means for locally bringing the movable element into contact with the light source, in which the selection means comprise row and column electrodes and means for applying control voltage signals to the invention also relates to a display source, a movable element, and selection means for locally bringing the movable element into contact with the light source, in which the selection means comprise row and column electrodes and means for applying control voltage signals to the row and column electrodes. Because of a minimum switching time of pixels, not all pixels, i.e. lines can be activated immediately when the display screen is addressed line by line.

Abstract: A system for supplying a liquid or paste-like substance. The system comprises a compressible bag for receiving the substance to be supplied, a supply assembly which forms a supply channel with a corresponding supply mouth for supplying the substance from the bag, and a container. The container has a supporting body comprising at least a supporting plate and a movable presser plate, wherein the supporting body and the presser plate together form a chamber for the incorporation therein of the bag, so that the bag is positioned between the supporting plate and the presser plate. The presser plate can be moved in a pressure direction to the supporting plate to empty the substance from the bag. The supporting body in a region between the supporting plate and the presser plate is provided with a passage for the supply assembly.

Abstract: The present invention relates to a method for processing an analog signal. The method involves hiding a digital watermark signal in the analog signal by combining the watermark signal with the analog signal (103). The watermark signal may be detected and extracted by a device (108) receiving the analog signal. The method includes embedding a key in the watermark signal, such that the key may be extracted and used by an encoding device (108) for encrypting digital content that is based on the analog signal. The invention also relates to an encoding device, which is arranged to perform such encryption.

Abstract: Process for the preparation of a compound with enhanced optical purity wherein a mixture of the enantiomers of a chiral compound of formula 1 wherein: R1 represents an alkyl or an aryl group R2 represents H, an alkyl or an aryl group Y represents an alkyl group, an aryl group, (CH2)nCOOH, (CH2)n—COOR, (CH2)n—CONRR?, CH2OH, or C?N wherein R and R? independently represent H, an alkyl or aryl group, and n represents 0 or 1, is brought into contact with an enzyme having peptide deformylase activity with a bivalent metal ion as a cofactor wherein the metal is chosen from the groups 5–11 of the periodic system, or for the preparation of a formylated compound with enhanced optical purity from a mixture of the enantiomers of the corresponding not formulated chiral compound in the presence of a formylation agent. Preferably the peptide deformylase is chosen from the class EC 3.5.2.27 or EC 3.5.1.31, and contains the sequences of (I) HEXXH, (ii) EGCLS and (iii) GXGXAAXQ.

Abstract: A method is proposed for measuring water permeability of substrates (1). A reactive compound (Ca, Ba) which reacts with a diffusing material, e.g. water, is applied on the substrate and the change in time of transmissivity, reflectivity of the layer is monitored in time.

Abstract: The invention relates to compounds of Formula (1), in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceutical active compounds.