Abstract: A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount.

Abstract: Banking software application development includes defining a plurality of banking object terms, each of these terms relating to components of a banking relationship. Additionally, the software is developed by defining a plurality of responsibility area terms, each of these terms relating to banking activities, wherein each of the responsibility area terms includes at least one of the banking object terms. From the defined relationships, the software is developed by generating a solution foundation for at least one of the responsibility area terms by defining relationships between the plurality of business object terms. Therefore, the banking software application is developed based on the solution foundation.

Abstract: Maleimide and succinimide derivatives were found to be effective topoisomerase II catalytic inhibitors. Due to this property, the maleimide and succinimide derivatives were investigated for their use as cytostatic agents and thus in the treatment of cancer. The compounds of the invention can be used in combination treatments with other cytostatic agents, such as topoisomerase II poisons. The maleimide and succinimide derivatives, due to their effective topoisomerase II catalytic inhibitory activity, are also useful as extravasation agents, such as upon administration of a topoisomerase II poison.

Abstract: The present invention relates to a method of treatment of a tumour cell which comprises administering to a subject in need of treatment an effective amount of a topoisomerase-II poison, e.g. etoposide, in combination with a bis-dioxypiperazine, e.g. dexrazoxane wherein said subject is further treated with radiation.

Abstract: A method of managing power used by a recording medium is disclosed. The recording medium receives a maximum current value and limits its operation to consume up to the maximum current value during a given storage operation. The recording medium may comprise a storage module coupled to a controller. The controller in the recording medium may receive the maximum current value and limit the operation of the recording medium to the maximum current value.

Abstract: Disclosed are compositions and methods for modulating hemichannel function in a cell, tissue or organ. The invention also relates to useful screens for detecting such compounds, particularly those capable of modulating connexin phosphorylation. Further provided are therapeutic methods for preventing or treating conditions impacted by undesired hemichannel function in a mammal such as heart arrhythmia.

Abstract: A system for discharging inert gas for extinguishing or suppressing a fire is disclosed. A fluid discharge control arrangement is positioned in a fluid flow path between a pressurised gas supply 10A,10B,10C and the target fire suppression zone 20. The fluid discharge control arrangement reduces the pressure in the fluid flow path downstream thereof. This may allow the downstream pipework to be selected to withstand a lower pressure than in a conventional system in which the fluid discharge control device was not provided, thereby reducing costs. The fluid discharge control device may comprise a first valve 30 and first restrictor 26 in the first flow path 22 and a second valve 32 and a second restrictor 28 provided in the second flow path 24. Fluid from the containers 10A,10B,10C flows initially through flow path 24 and restrictor 26. Subsequently flow path 22 may be closed by optional valve 30, and flow path 24 is opened by valve 32. Fluid flow then passes through restrictor 28.

Abstract: Systems and methods are provided for computing migration and performance matrices. The matrices may provide risk and performance data, as well as different views on the data useful for making and monitoring investment decisions. The migration and performance matrices may bring together data to reflect information on the likelihood that a rated entity will change its current rating within a given time period, information reflecting retention rates, and information describing the effect of changed exchanged rates on different data, for example.

Abstract: Systems and methods are provided for administrating funding of product development. The system may include a memory for storing a set of instructions and a processor for executing the set of instructions stored in memory to performed a method including establishing a list of entries; assigning a priority to each entry in said list; associating identifying information with at least one entry; and issuing an instruction upon determination that a predetermined condition has been fulfilled.

Abstract: The disclosed invention is a fixed bed ion exchange water purification system. It employs a combination of electronically controlled process steps and specific systems configurations to duplicate the effects of moving resin beds from one operating position to another as is required in moving bed ion exchange water purification systems. The invention combines features of single fixed bed ion exchange systems with those of a moving bed system. The invention applies to the treatment of water having typical industrial and drinking water concentrations of various ions.

Abstract: A method of managing power used by a recording medium is disclosed. The recording medium receives a maximum current value and limits its operation to consume up to the maximum current value during a given storage operation. The recording medium may comprise a storage module coupled to a controller. The controller in the recording medium may receive the maximum current value and limit the operation of the recording medium to the maximum current value.

Abstract: Methods and systems for removing perchlorate from water are disclosed. They involve: Methods and systems for removing perchlorate from water are disclosed which involve the use of a plurality of vessels containing an ion exchange resin having affinity for perchlorate ions, and in which perchlorate-contaminated water is passed over the resin in some but not all of the plurality of vessels operating in parallel to one another thereby removing perchlorate ion from the water stream and generating reduced perchlorate content product water streams and in which a subset of the plurality of vessels is removed from service, their resin is removed and replaced and they are returned to service.

Abstract: A method and system for the erasing of data from a non-volatile recording medium includes a non-volatile recording medium controller, a non-volatile recording medium, and a CPU. A data pattern used in an erasure command is sent to the non-volatile recording medium a single time. Consequently, the amount of data transferred to the non-volatile recording medium controller is reduced to a minimum. After receiving the erasure command, the non-volatile recording medium controller overwrites an erasure area with the data pattern.

Abstract: The present invention provides a method for automatically defining a part model for a semiconductor component. An image of the component is provided. The automatic method may be any of a trial and error method, systematic method or a method based on distance-angle signatures. The trial and error method is described in the context of defining a part model for a ball grid array. The systematic approach is described in the context of a leaded semiconductor, and the distance angle signature approach is described in the context of defining a part model for an odd form semiconductor component.

Abstract: The production of biomass or a desired product from a cell can be improved by inducing conversion of ATP to ADP without primary effects on other cellular metabolites or functions which is achieved by expressing an uncoupled ATPase activity in said cell and incubating the cell with a suitable substrate to produce said biomass or product. This is conveniently done by expressing in said cell the soluble part (F1) of the membrane bound (F0F1 type) H+-ATPase or a portion of F1 exhibiting ATPase activity. The organism from which the F1 ATPase or portions thereof is derived, or in which the F1 ATPase or portions thereof is expressed, may be selected from prokaryotes and eukaryotes.

Abstract: Systems and methods for removing perchlorate load from ion exchange resin regeneration brines.

Abstract: Centralized process context and information context are provided for a computer system having an enterprise service architecture platform. The process context is a centrally accessible object storing and providing status data generated during performance of a process flow. The process context permits firm personnel to review performance of the process flow, for example, to determine its status and to identify any business exceptions that may have occurred therein. The information context caches information generated during performance of the process flow. It provides data on which to assess firm performance parameters, for example, time elapsed during performance of each process step and it provides a detailed set of information describing the process business activity. The process context and information context support higher-level monitoring functions.

Abstract: The disclosed invention is a fixed bed ion exchange water purification system. It employs a combination of electronically controlled process steps and specific systems configurations to duplicate the effects of moving resin beds from one operation position to another as is required in moving bed ion exchange water purification systems. The invention combines features of single fixed bed ion exchange systems with those of a moving bed system. The invention applies to the treatment of water having typical industrial and drinking water concentrations of various ions.

Abstract: The invention provides novel compounds which are capable of stimulating the proliferation or/and the outgrowth from cells presenting the neural cell adhesion molecule (NCAM). Additionally, the invention relates to methods for treatment of normal, degenerated and damaged NCAM presenting cells.

Abstract: Disclosed is a cylindrical piston press foot mounted on a coupling element having a part with an enlarged diameter connected through a part with reduced diameter to the end of a piston rod. The device is useful in injection devices, mespecially devices by which a liquid medication is apportioned in individual doses from a cartridge.