Patents by Inventor Peter John Harrington

Peter John Harrington has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 4?-azido cytidine derivatives
    Patent number: 7632940
    Abstract: The invention relates to a novel process for the preparation of 4?-azido-cytidine (I) or a pharmaceutically accepted salt thereof. The compound of formula I is useful for treating virus mediated diseases, particularly for treating HCV mediated diseases.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: December 15, 2009
    Assignee: Roche Palo Alto LLC
    Inventors: Peter John Harrington, Stefan Hildbrand, Keshab Sarma
  • Process for the preparation of 4'-Azido cytidine derivatives
    Publication number: 20080161550
    Abstract: The invention relates to a novel process for the preparation of 4?-azido-cytidine (I) or a pharmaceutically accepted salt thereof. The compound of formula I is useful for treating virus mediated diseases, particularly for treating HCV mediated diseases.
    Type: Application
    Filed: December 7, 2007
    Publication date: July 3, 2008
    Inventors: Peter John Harrington, Stefan Hildbrand, Keshab Sarma
  • Process for preparation of pyridine derivatives
    Patent number: 7288658
    Abstract: The present invention relates to a process for the manufacture of compounds of formula wherein the substituents are as described herein which comprises the steps of a) reacting a compound of formula with a compound of formula to form a compound of formula b) converting the OH/?O function of compounds of formula XIV/XIVa into a leaving group P with a reagent containing a leaving group, selected from POCl3, PBr3, MeI and (F3CSO2)2O to form a compound of formula wherein P is halogen or trifluoromethanesulfonate; c) substituting R2 for the leaving group P by reacting compound XV with HR2 to form a compound of formula and d) hydrolyzing the nitrile function in an acidic medium selected from H2SO4, HCl and acetic acid, to form a compound of formula I The compounds of formula I are valuable intermediates for the manufacture of therapeutically active compounds which have NK-1 antagonist activity.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: October 30, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Wolfgang Goehring, Peter John Harrington, Lewis M Hodges, David A Johnston, Goesta Rimmler