Abstract: The invention relates to a composition and method for treating infections, preventing infections, reducing the likelihood of infections, or reducing the severity of infections in the sinonasal tract, by topically administering a composition comprising glycerol. The invention also relates to a method for supporting a healthy sinonasal microbiome, comprising topically administering a composition comprising glycerol. The invention also relates to a method for promoting the growth of commensal bacteria and inhibiting the growth of pathogenic bacteria in the sinonasal tract, comprising topically administering a composition comprising glycerol.

Abstract: A haemostat agent in the form of a multi-layer patch comprising at least first and second layers, wherein said first layer comprises a composition comprising fibrous ?-chitin (which may be sourced from a marine source such as squid pens) and one or more biocompatible polymer (for example, a polyethylene glycol (PEG) polymer or sodium polyphosphate (PolyP)), and said second layer comprises a film layer comprising fibrous ?-chitin. In one particular application, the haemostat agent is used for treating carotid artery injury associated with endonasal surgery.

Abstract: The present disclosure relates to methods and products for reducing adhesions. In certain embodiments, the present disclosure provides a method of reducing adhesions in a subject, the method comprising exposing a region in the subject susceptible to formation of an adhesion to an agent having iron chelation and/or antioxidant activity, thereby reducing adhesions in the subject.

Abstract: The present disclosure relates to methods and products for reducing the viability of microorganisms, and to methods and products for preventing and/or treating microorganism infections. Certain embodiments of the present disclosure provide a method for reducing viability of a microorganism. The method comprises exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.

Abstract: A haemostat agent in the form of a multi-layer patch comprising at least first and second layers, wherein said first layer comprises a composition comprising fibrous ?-chitin (which may be sourced from a marine source such as squid pens) and one or more biocompatible polymer (for example, a polyethylene glycol (PEG) polymer or sodium polyphosphate (PolyP)), and said second layer comprises a film layer comprising fibrous ?-chitin. In one particular application, the haemostat agent is used for treating carotid artery injury associated with endonasal surgery.

Abstract: The present disclosure relates to methods and products for reducing adhesions. In certain embodiments, the present disclosure provides a method of reducing adhesions in a subject, the method comprising exposing a region in the subject susceptible to formation of an adhesion to an agent having iron chelation and/or antioxidant activity, thereby reducing adhesions in the subject.

Abstract: The present disclosure relates to methods and products for reducing the viability of microorganisms, and to methods and products for preventing and/or treating microorganism infections. Certain embodiments of the present disclosure provide a method for reducing viability of a microorganism. The method comprises exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.

Abstract: A composition suitable for use in wound healing, particularly for reducing post-surgical adhesions, containing cross-linked derivatives of chitosan and dextran polymers. A hydrogel forms when solutions of the polymers are combined.

Abstract: A composition suitable for use in wound healing, particularly for reducing post-surgical adhesions, containing cross-linked derivatives of chitosan and dextran polymers. A hydrogel forms when solutions of the polymers are combined.

Abstract: The invention provides a hydrogel suitable for use in wound healing, particularly for reducing post-surgical adhesions. The hydrogel comprises cross-linked derivatives of chitosan and dextran polymers. The hydrogel forms when solutions of the polymers are combined.