Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.

Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.

Abstract: The invention relates to analyte monitoring/drug delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The invention can optionally provide for calibration without intervention of the user and can also provide for semi-continuous monitoring for day and night time. The invention can provide up to four, or more, weeks of operation. The invention can provide for a device that is relatively small in size, and therefore unobtrusive. The invention can also provide for device with remote control and interactive electronics. The invention may be also used for the delivery of various pharmaceutical agents.

Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.

Abstract: A device detects the location of patterned objects in an environment by receiving an optical image and converting the optical image of the lost object into a color digital image. The device employs software to perform an analysis of the color digital image to detect the location of the one or more patterned objects in the environment by using color characteristics of light reflected from a pattern on the one or more patterned objects. The software uses a range of the visible portion of the color space uniquely identified for the light reflected from the pattern on the object and identifies those pixels in the digital image that may be possible targets.

Abstract: Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Abstract: Imaging circuitry integrated into a golf club head, such as a putter, obtains an image from as the golf club head strikes a golf ball as well as successive images after the golf ball is struck, such n<5. The images can be analyzed by integral computational software provided in the imaging device operable to (i) analyze whether the ball was struck in the middle of the golf club head, (ii) whether the golf club head was square to the target and (iii) based on comparison of n successive images, calculate the immediate path of the golf ball.

Abstract: A one dimensional (1D) line imaging system that operates at a scanning (clock) rate of between 10-40 MHz is used to monitor the characteristics of a golf swing. A line image is analyzed in real time by an associate computer imaging system removing the need for a trigger to operate. Optics of the imaging system are designed to relate ball image size to distance so that the number of 1 D pixels imaging the ball, in particular sensing a white object, have a relation to distance to the ball. Ball image size is related to distance by monitoring the rate of increase (rate of change) of the pixels imaging the ball with time so that the speed of the club head can be determined. The speed of a golf ball that has been struck is determined by monitoring the rate of decrease (rate of change) of the pixels imaging the ball.

Abstract: A device detects the location of objects in an environment by receiving an optical image and converting the optical image of the lost object into a color digital image. The device employs software to perform an analysis of the color digital image to detect the location of the one or more objects in the environment by using color and shape characteristics of the one or more objects. The software uses a range of the visible portion of the color space uniquely identified for the type of object in that environment and identifies those pixels in the color digital image that may be possible targets. Intensity of background and object size are used to exclude pixels as possible target objects.

Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.

Abstract: Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Abstract: Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Abstract: In one embodiment, a tunable microfluidic device comprises at least one optical resonant cavity having a microfluidic channel disposed through a center thereof. At least one fluid is manipulated within the channel to change or “tune” an optical characteristic of the optical resonant cavity. In further embodiments, the tunable microfluidic device is incorporated into systems for assaying biological and/or chemical samples and for optical switching and/or filtering.

Abstract: The invention relates to analyte monitoring/drug (pharmaceutical agent) delivery device. The invention is suited for monitoring various blood constituents such as glucose. The device has a housing that at least partially encloses a plurality of microneedles disposed on a carrier and an electronics portion. Each microneedle is in fluid communication with a corresponding microchannel. Each microneedle is individually addressable. That is, each microneedle can be extended and retracted individually via an actuator. The electronics portion includes a processor and associated circuitry (e.g., memory, supporting electronics and the like), a motor or the like, a sensor, a power supply (e.g., battery) and optionally an interface. In general, the processor controls the operation of the device and is data communication with the actuator, motor, sensor and interface. The invention provides for autonomous operation, that is, without intervention of the user.

Abstract: Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Abstract: Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Abstract: A spraying device for dispensing electrostatic liquid droplets includes a container holding a liquid at one end, and having a nozzle assembly with an aperture at another end. The nozzle assembly includes a longitudinal hollow tube terminating in a metallic structure. The metallic structure includes a metallic base plate having at least one aperture formed therein for fluid communication with the hollow tube. The longitudinal hollow tube includes an end inserted in the liquid. A charge accumulator disposed in the liquid accumulates electrostatic charges. A wire conductor between the base plate and the charge accumulator transfers the electrostatic charges from the liquid to the nozzle assembly.

Abstract: Provided is an analyte monitoring device having a housing, the device comprising: a plurality of needles, each having a tip, a retracted position, a position wherein the tip is extended from the housing a distance adapted to pierce skin; an electrically or spring powered needle pushing apparatus movable to separately engage each of the needles to move each from the retracted position to the extended position; an energy source located within the housing; a plurality of analysis sites comprising an analysis preparation, each adapted to receive liquid from the needles to wet the analysis preparation; one or more light sources adapted to direct light at the analysis sites; one or more light detectors adapted to receive light from the analysis sites; and a processor.

Abstract: An apparatus for switching an optical signal comprising a first optical waveguide, a second optical waveguide aligned with the first and a third optical waveguide intersecting the previously mentioned pair. At the region of intersection of the waveguides, a microchannel containing a liquid is disposed. Also included in the microchannel is an electrokinetic pump used to move the fluid into and out of the microchannel.

Abstract: An optical switch comprising a fluid contained within a reservoir having a characteristic, a plurality of waveguides are located proximate to the fluid and an actuator is coupled to the fluid for changing the characteristic of the fluid to switch a light signal from one waveguide to another waveguide.