Patents by Inventor Peter K. S. Siegl

Peter K. S. Siegl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6410554
    Abstract: This invention relates to combination therapy for the treatment of benign prostatic hyperplasia comprising an alpha-1a antagonist and an endothelin antagonist. More specifically, the use of a selective alpha-1a adrenergic receptor antagonist in combination with a subtype non-selective endothelin antagonist provides relief of lower urinary tract symptoms in patients with symptomatic prostatism or benign prostatic hyperplasia. This combination therapy improves lower urinary tract symptoms including increasing urine flow rate, decreasing residual urine volume and improving overall obstructive and irritative symptoms in patients with benign prostatic hyperplasia or symptomatic prostatism.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: June 25, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Theodore P. Broten, Peter K. S. Siegl, Steven A. Nichtberger
  • Patent number: 5817658
    Abstract: A method for the treatment of Meniere's disease comprising the administration of a medicament which modulates the IKs channel of the ear and thereby reducing endolymph production.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: October 6, 1998
    Assignee: Merck & Company, Inc.
    Inventors: Peter K. S. Siegl, Allan I. Goldberg, Michael R. Goldberg, Paul I. Chang
  • Patent number: 5444067
    Abstract: This invention relates to compounds represented by formula I: ##STR1## which are agonists of angiotensin II. The invention is also concerned with the use of aforementioned agonists in the treatment of states meditated by angiotensin.
    Type: Grant
    Filed: August 30, 1993
    Date of Patent: August 22, 1995
    Assignee: Merck & Co., Inc.
    Inventors: Salah Kivlighn, Victor J. Lotti, Ralph A. Rivero, Peter K. S. Siegl, Gloria J. Zingaro
  • Patent number: 4604394
    Abstract: Pharmaceutical compositions and methods useful in the treatment of cardiac arrhythmias are described.
    Type: Grant
    Filed: October 1, 1984
    Date of Patent: August 5, 1986
    Assignee: Merck & Co., Inc.
    Inventors: Gregory J. Kaczorowski, Peter K. S. Siegl