Abstract: Pharmaceutical compositions of the invention comprise kinase inhibitors having a disease-modifying action in the treatment of diseases associated with BCR-ABL activity that include cancer, including chronic myeloid leukemia, acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, lymphomas, and metastatic carcinoma.

Abstract: Pharmaceutical compositions of the invention comprise kinase inhibitors having a disease-modifying action in the treatment of diseases associated with BCR-ABL activity that include cancer, including chronic myeloid leukemia, acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, lymphomas, and metastatic carcinoma.

Abstract: Pharmaceutical compositions of the invention comprise kinase inhibitors having a disease-modifying action in the treatment of diseases associated with BCR-ABL activity that include cancer, including chronic myeloid leukemia, acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, lymphomas, and metastatic carcinoma.

Abstract: Pharmaceutical compositions of the invention comprise kinase inhibitors having a disease-modifying action in the treatment of diseases associated with BCR-ABL activity that include cancer, including chronic myeloid leukemia, acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, multiple myeloma, lymphomas, and metastatic carcinoma.

Abstract: According to one aspect, driver management is provided. One or more speech segments of a driver of an autonomous vehicle may be recorded. A position, a destination, or a previous destination of a driver or an autonomous vehicle may be tracked. An estimated state of the driver may be determined based on one or more of the speech segments, the position, the destination, or the previous destination, and a calendar event associated with the driver or a passenger of the autonomous vehicle. Autonomous driving features may be automatically enabled, disabled, or operation of the autonomous vehicle may be enabled or disabled in different modes based on the estimated state of the driver. Additionally, notifications may be displayed, rideshare applications may be launched, or warnings may be sent based on the estimated state of the driver.

Abstract: According to one aspect, driver management is provided. One or more speech segments of a driver of an autonomous vehicle may be recorded. A position, a destination, or a previous destination of a driver or an autonomous vehicle may be tracked. An estimated state of the driver may be determined based on one or more of the speech segments, the position, the destination, or the previous destination, and a calendar event associated with the driver or a passenger of the autonomous vehicle. Autonomous driving features may be automatically enabled, disabled, or operation of the autonomous vehicle may be enabled or disabled in different modes based on the estimated state of the driver. Additionally, notifications may be displayed, rideshare applications may be launched, or warnings may be sent based on the estimated state of the driver.

Abstract: A conversation recognition system on board a vehicle includes an acoustic sensor component that detects sound in a cabin of the vehicle, a voice recognition component coupled to the acoustic sensor component that analyzes the sound detected by the acoustic sensor component and identifies a plurality of utterances, and a conversation threading unit coupled to the voice recognition component that analyzes the utterances identified by the voice recognition component and identifies a plurality of conversations between a plurality of occupants of the vehicle. The conversation recognition system enables multiple conversations in an environment to be recognized and distinguished from each other.

Abstract: A rotary position sensor includes a member with a shaft associated with the member such that movement of the member rotates the shaft. An arc-shaped permanent magnet is coupled to a periphery of the shaft for rotation therewith. First and second adjacent magnetic field concentrators define a gap there-between. Sensor structure is disposed in the gap. Upon movement of the member causing rotation of the shaft and magnet, the concentrators and sensor structure remain stationary, with the magnet providing a magnetic pole that changes the magnetic field in the gap. The sensor structure is constructed and arranged to respond to the changes in the magnetic field to identify a position of the member.

Abstract: A rotary position sensor includes a member with a shaft associated with the member such that movement of the member rotates the shaft. An arc-shaped permanent magnet is coupled to a periphery of the shaft for rotation therewith. First and second adjacent magnetic field concentrators define a gap there-between. Sensor structure is disposed in the gap. Upon movement of the member causing rotation of the shaft and magnet, the concentrators and sensor structure remain stationary, with the magnet providing a magnetic pole that changes the magnetic field in the gap. The sensor structure is constructed and arranged to respond to the changes in the magnetic field to identify a position of the member.

Abstract: The present invention relates to derivatives of aroyl-O-piperidine structure of the general formula (I): in which R1, R2, R3 and R4 are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia, and to the prevention or treatment of obesity.

Abstract: The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2?, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.

Abstract: The present invention relates to derivatives of aroyl-O-piperidine structure of the general formula (I): in which R1, R2, R3 and R4 are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia, and to the prevention or treatment of obesity.

Abstract: The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2?, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.

Abstract: The present invention relates to a compound of the formula (I): in which T, A, R, B Xi, Yi and n are as defined in Claim 1, and to the pharmaceutically usable derivatives, solvates and stereoisomers thereof, comprising a mixture thereof in all proportions, which can be used in the treatment of dyslipidaemia, and to pharmaceutical compositions comprising them.

Abstract: A device for bending strips of metal includes a pair of cooperating holding strips adjustably mounted on a support platform. A plate orienting means selectively positions the holding plates with respect to each other, allowing the plates to hold a metal strip during the bending process. An tapered press wedge is rotatably mounted on the support platform and cooperates with the holding plates to allow operator-controlled bending of the strip secured by the holding plates. An articulation handle incorporated into the press wedge allows an operator to produce the leverage sufficient to bend the strip. The device allows an operator to make either a single bend or a series of bends with equal ease.