Patents by Inventor Peter Kastner

Peter Kastner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210239712
    Abstract: The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of FGFBP-1 in a sample from the subject, and comparing the amount of FGFBP-1 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to methods for the prediction of stroke based on the amount of FGFBP-1.
    Type: Application
    Filed: February 22, 2021
    Publication date: August 5, 2021
    Inventors: Peter Kastner, Andre Ziegler, Ursula-Henrike Wienhues-Thelen, Vinzent Rolny, Manuel Dietrich, Ulrich Schotten
  • Publication number: 20210215716
    Abstract: The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of SPON-1 in a sample from the subject, and comparing the amount of SPON-1 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to methods for the prediction of stroke based on the amount of SPON-1.
    Type: Application
    Filed: February 22, 2021
    Publication date: July 15, 2021
    Applicants: Roche Diagnostics Operations, Inc., Universiteit Maastricht, Academisch Ziekenhuis Maastricht
    Inventors: Peter Kastner, Manuel Dietrich, André Ziegler, Ursula-Henrike Wienhues-Thelen, Vinzent Rolny, Ulrich Schotten
  • Publication number: 20210190801
    Abstract: The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of BMP 10 in a sample from the subject, and comparing the amount of BMP 10 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to a method for diagnosing heart failure based on the determination of BMP 10 in a sample from a subject. Further, the present invention relates to a method for predicting the risk of a subject of hospitalization due to heart failure based on the determination of a BMP 10-type peptide in a sample from a subject.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 24, 2021
    Inventors: Johann Karl, Peter Kastner, Ursula-Henrike Wienhues-Thelen, Manuel Dietrich, Andre Ziegler, Ulrich Schotten
  • Publication number: 20210181211
    Abstract: The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of TFPI-2 in a sample from the subject, and comparing the amount of TFPI-2 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to methods for assessing anticoagulation therapy and to methods for predicting the risk of stroke of a subject. Said methods are based on the determination of the amount of TFPI-2 in a sample from the subject.
    Type: Application
    Filed: February 16, 2021
    Publication date: June 17, 2021
    Inventors: Peter Kastner, Andre Ziegler, Ursula-Henrike Wienhues-Thelen, Vinzent Rolny, Manuel Dietrich, Ulrich Schotten
  • Publication number: 20210172962
    Abstract: The present invention relates to a method for assessing the risk of stroke in a subject, said method comprising the steps of determining the amount of CES-2 in a sample from the subject, and comparing the amount of CES-2 to a reference amount, whereby the risk of stroke is to be assessed. Moreover, the present invention relates to a method for assessing the efficacy of an anticoagulation therapy and a method for identifying a subject being eligible to the administration of at least one anticoagulation medicament or being eligible for increasing the dosage of at least one anticoagulation medicament.
    Type: Application
    Filed: February 10, 2021
    Publication date: June 10, 2021
    Inventors: Manuel Dietrich, Peter Kastner, Vinzent Rolny, Ulrich Schotten, Ursula-Henrike Wienhues-Thelen, Andre Ziegler
  • Publication number: 20210156875
    Abstract: The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of DKK3 in a sample from the subject, and comparing the amount of DKK3 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to a method for diagnosing heart failure and/or at least one structural or functional abnormality of the heart associated with heart failure.
    Type: Application
    Filed: January 29, 2021
    Publication date: May 27, 2021
    Applicants: Roche Diagnostics Operations, Inc., Universitaet Maastricht, Academisch Ziekenhuis Maastricht
    Inventors: Johann Karl, Peter Kastner, Roberto Latini, Vinzent Rolny, Ursula-Henrike Wienhues-Thelen, Andre Ziegler, Manuel Dietrich, Jennifer Meessen, Ulrich Schotten
  • Publication number: 20200300869
    Abstract: The present disclosure demonstrates a method for predicting the risk of stroke of a subject and a method for improving the prediction accuracy of a clinical stroke risk score. The methods are based on the determination of the amount of Angiopoietin-2 (Ang-2) and/or the amount of Insulin-like growth factor-binding protein 7 (IGFBP7) in a sample from a subject. Moreover, disclose is the use of i) the biomarker Ang-2 and/or the biomarker IGFBP7, and/or ii) at least one detection agent that specifically binds to Ang-2 and/or at least one detection agent that specifically binds to IGFBP7 in a sample from a subject for predicting the risk of stroke of said subject.
    Type: Application
    Filed: June 12, 2020
    Publication date: September 24, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Ursula-Henrike Wienhues-Thelen, Johann Karl, Peter Kastner, Vinzent Rolny, Andre Ziegler, David Conen
  • Publication number: 20200116708
    Abstract: Disclosed is a method for diagnosing paroxysmal atrial fibrillation in a subject, involving: determining the amount of FABP-3 (Fatty acid binding protein 3) in a sample from a subject suspected to suffer from paroxysmal atrial fibrillation, and comparing the determined amount to a reference amount. The method may further involve the determination of a BNP-type peptide. Also disclosed is a device adapted to carry out the method.
    Type: Application
    Filed: December 12, 2019
    Publication date: April 16, 2020
    Applicants: Roche Diagnostics Operations, Inc., Maastricht University Medical Center
    Inventors: Johann Karl, Peter Kastner, Vinzent Rolny, Ursula-Henrike Wienhues-Thelen, Manuel Dietrich, Andre Ziegler, Ulrich Schotten
  • Patent number: 10600338
    Abstract: A method and an apparatus for demonstrating optical properties of a lens for spectacle glasses are disclosed. A demonstrational tool exposes a spectacle lens or a pair of spectacle glasses to polarized light to demonstrate how the removal of polarized, reflected light from a display reduces glare. Further, the demonstrational tool exposes a phototrope lens or a pair of spectacle glasses with phototrope lenses to UV- or HEV-light to demonstrate the reversible self-tinting of the phototrope lenses.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: March 24, 2020
    Assignee: Carl Zeiss Vision International GmbH
    Inventor: Peter Kastner
  • Publication number: 20190353666
    Abstract: The present disclosure relates to a method for predicting the risk of recurrence of Atrial Fibrillation in a subject based on determining the amount of the biomarker Angiopoietin-2 (Ang-2) and optionally of at least one further biomarker in a sample from the subject. The present disclosure also contemplates a method of diagnosing Atrial Fibrillation in a subject suspected to suffer from Atrial Fibrillation based on determining the amount of the biomarker Angiopoietin-2 (Ang-2) and optionally of at least one further biomarker in a sample from the subject. Further envisaged are devices adapted to carry out the method of the present disclosure.
    Type: Application
    Filed: December 12, 2018
    Publication date: November 21, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Herbert Andres, Dirk Block, Johann Karl, Peter Kastner, Ursula-Henrike Wienhues-Thelen, Roberto Latini, Serge Masson, Andre Ziegler, Edelgard Kaiser, Stefan Palme, Markus Thomas, Simona Barlera
  • Publication number: 20190213916
    Abstract: A method and an apparatus for demonstrating optical properties of a lens for spectacle glasses are disclosed. A demonstrational tool exposes a spectacle lens or a pair of spectacle glasses to polarized light to demonstrate how the removal of polarized, reflected light from a display reduces glare. Further, the demonstrational tool exposes a phototrope lens or a pair of spectacle glasses with phototrope lenses to UV- or HEV-light to demonstrate the reversible self-tinting of the phototrope lenses.
    Type: Application
    Filed: January 10, 2018
    Publication date: July 11, 2019
    Inventor: Peter Kastner
  • Publication number: 20190162737
    Abstract: The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of ESM-1 in a sample from the subject, and comparing the amount of ESM-1 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to a method for diagnosing heart failure and/or at least one structural or functional abnormality of the heart associated with heart failure.
    Type: Application
    Filed: February 1, 2019
    Publication date: May 30, 2019
    Applicants: Roche Diagnostics Operations, Inc., Maastricht University Medical Center
    Inventors: Johann Karl, Peter Kastner, Roberto Latini, Serge Masson, Ursula-Henrike Wienhues-Thelen, Andre Ziegler, Manuel Dietrich, Ulrich Schotten, Vinzent Rolny
  • Publication number: 20190155377
    Abstract: A method determines the time required for a timed up and go test and for verifying an ascertained result. A distance measuring device is provided which continuously measures the distance from a subject located in front of a chair to the backrest of the chair and which forwards the distance to a control unit. The chair is positioned in particular at a specified distance to a wall, an obstacle, or a marking. The measured distance values recorded by the distance measuring device are continuously recorded. The subject is instructed to stand up from the chair, walk forwards, in particular towards the wall, the obstacle, or the marking, and then turn around, in particular in front of the wall, the obstacle, or in the region of the marking, and sit back down on the chair. The subject carries out these instructions to the best of their ability.
    Type: Application
    Filed: May 31, 2017
    Publication date: May 23, 2019
    Inventors: ROBERT MODRE-OSPRIAN, PETER KASTNER, GUENTER SCHREIER, ALBERTO SANCHEZ SANCHEZ
  • Publication number: 20180231570
    Abstract: The present disclosure describes a method for predicting the risk of a patient to suffer from acute kidney injury (AKI) during or after a surgical procedure or after administration of a contrast medium. The method is based on the determination of the level of the biomarker IGFBP7 (Insulin-like Growth Factor Binding Protein 7) in a body fluid sample obtained from the patient prior to the surgical procedure or prior to the administration of a contrast medium. Further, the present disclosure describes a method for predicting the risk of a patient to suffer from acute kidney injury (AKI) based on the determination of the amount of the biomarker IGFBP7 (Insulin-like Growth Factor Binding Protein 7) and Cystatin C in a body fluid sample obtained from the patient. The present disclosure further encompasses kits and devices adapted to carry out the methods of the disclosed methods.
    Type: Application
    Filed: April 2, 2018
    Publication date: August 16, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Andrea Horsch, Birgit Klapperich, Dirk Block, Alfred Engel, Johann Karl, Rosemarie Kientsch-Engel, Ekaterina Manuilova, Christina Rabe, Sandra Rutz, Monika Soukupova, Ursula-Henrike Wienhues-Thelen, Peter Kastner, Edelgard Anna Kaiser
  • Publication number: 20150355199
    Abstract: The present invention relates to an assay for specific detection of complement factor H-related protein 1 (CFHR1) in a sample from a subject, as well as kits and agents related thereto.
    Type: Application
    Filed: August 26, 2015
    Publication date: December 10, 2015
    Inventors: Alfred Engel, Andreas Gallusser, Johann Karl, Peter Kastner, Wolfgang Obermeier, Monika Soukupova
  • Publication number: 20140065610
    Abstract: An in vitro method of predicting whether a patient, having a neurodevelopmental, neurological or neuropsychiatric disorder, will derive a clinical benefit if treated with a glycine reuptake inhibitor (GRI), via determination of the protein concentration of one, two, three, four five or six members of the complement factor H family or a mixture or a combination thereof and comparison against a representative value, wherein a higher value of the protein concentration in the patient's sample against the representative value is indicative of a patient whom will derive clinical benefit from treatment with GRI.
    Type: Application
    Filed: August 21, 2012
    Publication date: March 6, 2014
    Inventors: Laurent Essioux, Carsten Horn, Johann Karl, Peter Kastner, Fabian Model, Giuseppe Palermo, Christina Rabe, Daniel Umbricht, Gabriel Vargas, Anne Vogt
  • Publication number: 20080005921
    Abstract: The invention relates to a device and a method for producing and/or transforming a web of fibrous material, in particular a paper or cardboard web. Said device includes a heatable and rotatable cylinder, in particular a drying cylinder of a drying section, and a cylinder sleeve which can be impinged from the inside by a heating fluid. In order to improve the heating power below the external surface of the cylinder sleeve, at least one channel is provided in order to guide the heating fluid.
    Type: Application
    Filed: July 5, 2007
    Publication date: January 10, 2008
    Inventors: Thomas Gruber-Nadlinger, Gunter Halmschlager, Christoph Haase, Herbert Boden, Norbert Karner, Peter Kastner, Gunter Seitlhuber, Gerhard Holtmann, Andreas Figerl, Rainer Kloibhofer, Erich Rollenitz